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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: EL271_RS05430 [old locus tag: SPOH_1000 ]
  • pan locus tag?: PNEUPAN002291000
  • symbol: rexB
  • pan gene symbol?: rexB
  • synonym:
  • product: ATP-dependent nuclease subunit B

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL271_RS05430 [old locus tag: SPOH_1000 ]
  • symbol: rexB
  • product: ATP-dependent nuclease subunit B
  • replicon: chromosome
  • strand: +
  • coordinates: 1006285..1009560
  • length: 3276
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018937 (1006285..1009560) NCBI
  • BioCyc: EL271_RS05430 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1015 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    ATGAAATTACTTTATACTGATATTCGAACTTCTTTGACAGAAATTCTAACAAGAGAGGCA
    GAAGAGCTAGTTGCAGCTGGCAAGCGGGTCTTCTACATTGCCCCCAACTCTCTTTCTTTT
    GAAAAGGAACGCGCCGTGCTGGAATGCTTGTCCCAGCAGGCTTCTTTTTCGATTACCGTC
    ACGCGCTTTGCTCAAATGGCTCGTTATCTGGTCTTGAATGATTTACCAGTTAAAACTACT
    CTTGATGATATCGGTCTTGGGTTGGCCTTTTACAAATGCCTTGCCGAACTCGATCCCAAG
    GACTTGCGTGTTTATGGCGCTATTAAGCAGGATCCTCAATTGATCCAGCAGTTAATTGAG
    CTTTACCATGAGATGACCAAATCTCAGATGAGTTTTTTGGACTTGGAGAATTTAACAGAT
    GAGGATAAGAGGACGGATTTACTCTTGATTTTTGAGAAAGTAACAGCCTATCTTAATCAA
    GGTCAGTTAGCCCAGGGAAGTCAGTTGTCCCATTTGATTGAGGCTATTGAGAATGACAAG
    GTAAGTAGTGATTTTAATCAAATCACCTTGGTCATTGACGGCTTTACTCGTTTTTCTGCT
    GAGGAAGAGCGGGTTGTGGACTTACTTCACGGCAAAGGTGTTGAGATTGTTATCGGGGCT
    TATGCTAGTAAGAAAGCCTATACCAGTCCTTTTAGCGAGGGCAATCTCTACCAAGCCAGC
    GTAAAATTTCTCCATCATCTGGCTTCTAAATACCAAACGCCTGCTCAGGACTGTTCTCAA
    ACTCATGAGAAGATGGATAGTTTTGACAAGGCCTCTCGTTTGTTGGAGTCTTCTTATGAC
    TTTTCAGAACTCGCTTTGGATGTCGATGAGAAAGACCGTGAAAATTTACAAATCTGGTCT
    TGTTTGACGCAAAAGGAGGAGTTGGAGCTAGTAGCCCGTAGCATTCGTCAGAAATTACAT
    GAGAACTCAGACCTGAGCTACAAGCATTTTCGTATTCTCTTGGGGGATGTAGCTTCTTAC
    CAGTTATCTCTCAAAACCATTTTTGACCAGTATCAGATTCCTTTTTATCTTGGTAGAAGC
    GAAGCCATGGCTCATCATCCCTTGACTCAGTTTGTCGAGTCTATTTTAGCTTTAAAACGT
    TACCGTTTTCGTCAGGAGGATTTGATTAATCTTCTTAGAACTGATTTGTATACTGACCTC
    AGTCAGTCTGATATTGATGCTTTTGAGCAATATATCCGCTATCTTGGTATCAATGGCTTG
    CCAGCCTTTCAGCAAACCTTCACCAAATCCCACCATGGAAAATTTAATCTTGAGCGTTTG
    AATGTCCTCCGCCTGAGAATTTTAGCACCTCTTGAAACCCTCTTTGCCAGCCGAAAACAA
    AAGGCTGAAAAACTCCTACAAAAATGGAGTGTCTTTCTAAAAGAAGGAGCTGTGACCAAG
    CAGTTACAAGATTTGACAACCACTTTGGAAGCTGTAGAACAGGAAAGACAAGCCGAAGTT
    TGGAAGGCTTTCTGCCATGTTTTAGAACAATTTGCGACTGTTTTTGCTGGTTCACAGGTT
    AGTCTGGAAGACTTCCTAGCCTTGCTCCATTCTGGAATGAGTTTGTCCCAATACCGTACC
    ATTCCAGCAACAGTGGACACTGTTCTGGTGCAGAGTTACGATTTGATTGCACCATTGACT
    GCTGACTTTGTCTATGCTATTGGACTAACTCAGGACAATTTACCAAAAATTTCTCAAAAC
    ACCAGTCTTCTGACAGATGAAGAAAGGCAAAACCTAAACCAAGCGACCGAAGAAGGCGTT
    CAATTACTGATTGCCAGCAGTGAAAATCTCAAGAAAAATCGCTACACTATGCTTTCCTTG
    GTCAATTCTGCTCGTAAGCAGTTGTTCTTGTCGGCTCCAAGCCTTTTTAACGAAAGTGAA
    AGTAAGGAATCTGCCTATCTTCAAGAGTTGATCCATTTTGGATTTAGGCGGAGAGAGAAG
    AGGATGAATCACAAAGGACTGTCTAAGGAGGATATGGGGTCCTATCACAGTCTTTTGTCT
    AGTCTGGTTGCCTATCACCAGCAGGGTGAGATGAGCGATACTGAGCAAGATTTGACTTTT
    GTCAAGGTTCTGTCGCGTGTCATAGGTAAAAAACTAGATCAGCAAGGTCTGGAAAATCCA
    GCCATCCCAATCAGTCCAAGCAGCAAGACCTTAGCCAAGGACACCTTGCAAGCTCTCTAT
    CCTGCCAAACAGGAGTTTTACCTGTCTACGTCGGGTTTGACAGAGTTTTATCGCAATGAA
    TACAGTTATTTCCTACGCTACGTTTTAGGCTTGCAGGAGGAATTACGTTTGCATCCTGAT
    GCCCGTAGTCACGGGAATTTCTTGCATCGTATCTTTGAACGCGCCTTACAGTTGCCTAAT
    GAAGATTCCTTTGACCAACGTCTAGAACAAGCTATTCAAGAAACCAGTCAAGAACGCGAA
    TTTGAAGCTATTTATCAAGAAAGTTTGGAAGCCCAGTTTACCAAGGAAGTTTTGCTTGAT
    GTTGCACGGACGACTGGACATATTCTCCGACACAATCCAGCCATCGAAACCATCAAAGAA
    GAAGCAAATTTTGGTGGAAAAGACCAAGCCTTTATTCAATTAGACAATGGACGCAGTGTC
    TTTGTACGAGGCAAGGTGGACCGGATTGACCGTTTGAAAGCTAATGGAGCGATAGGAGTA
    GTAGACTACAAATCCAGTCTGACTCAGTTCCAGTTTCCTCATTTCTTTAATGGGCTCAAT
    TCTCAGTTACCAACCTATCTTGCTGCCCTAAAAAGAGAAGGGGAGCAGAACTTTTTCGGC
    GCCATGTACTTGGAAATGGCTGAACCTGTCCAATCTCTGATGGCGGTAAAAAGTCTTGCA
    GGAGCAGTGGTAGAAGCCAGCAAATCTATGAAATACCAAGGGCTCTTCTTGGAAAAAGAA
    AGCAGTTATTTAGGCGAATTTTATAACAAAAACAAGGCTAATCAACTGACAGATGAGGAA
    TTTCAGCTCCTACTGGACTACAATGCCTATCTTTACAAGAAAGCTGCTGAGAAGATTTTA
    GCAGGCCGGTTCGCCATCAATCCTTATACTGAAAATGGCAGAAGCATTGCCCCATACGTC
    CAGCAACATCAGGCTATTACAGGCTTTGAAGCCAATTACCATCTGGGCCAAGCCCGTTTC
    CTAAAAAAGTTGGACCTAGCTGATAGCAAGCGTCTGGTCGGAGAAAAACTCAAGCAAGCT
    TGGCTTGAAAAAATAAGAGAGGAGTTGAATCGATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
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    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3276

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL271_RS05430 [old locus tag: SPOH_1000 ]
  • symbol: RexB
  • description: ATP-dependent nuclease subunit B
  • length: 1091
  • theoretical pI: 5.95236
  • theoretical MW: 124850
  • GRAVY: -0.359762

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent nuclease subunit B (TIGR02774; HMM-score: 1814.9)
    and 1 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair helicase-exonuclease AddAB, AddB subunit (TIGR02773; EC 3.1.-.-,3.6.4.12; HMM-score: 300.3)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PDDEXK (CL0236) PDDEXK_1; PD-(D/E)XK nuclease superfamily (PF12705; HMM-score: 101.5)
    and 3 more
    no clan defined Arg_decarb_HB; Arginine decarboxylase helical bundle domain (PF17810; HMM-score: 20.4)
    Med15_fungi; Mediator complex subunit 15 (PF05397; HMM-score: 12.8)
    DUF3106; Protein of unknown function (DUF3106) (PF11304; HMM-score: 10.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9425
    • Cytoplasmic Membrane Score: 0.0327
    • Cell wall & surface Score: 0.0165
    • Extracellular Score: 0.0084
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006323
    • TAT(Tat/SPI): 0.000623
    • LIPO(Sec/SPII): 0.000914
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000772360 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQGQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREELNR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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