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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: EL271_RS05950 [old locus tag: SPOH_1090 ]
  • pan locus tag?: PNEUPAN002442000
  • symbol: ptsP
  • pan gene symbol?: ptsI
  • synonym:
  • product: phosphoenolpyruvate--protein phosphotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL271_RS05950 [old locus tag: SPOH_1090 ]
  • symbol: ptsP
  • product: phosphoenolpyruvate--protein phosphotransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1108752..1110485
  • length: 1734
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018937 (1108752..1110485) NCBI
  • BioCyc: EL271_RS05950 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1039 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGACAGAAATGCTTAAAGGAATCGCAGCATCTGACGGTGTTGCAGTTGCAAAAGCATAT
    CTACTCGTTCAGCCGGATTTGTCATTTGAGACTATTACAGTCGAAGATACAAACGCAGAA
    GAAGCTCGCCTTGATGCCGCTCTACAGGCATCACAAGACGAGCTTTCTGTTATTCGCGAG
    AAAGCAGTAGGTACGCTCGGTGAAGAAGCAGCTCAAGTTTTTGATGCTCACTTAATGGTT
    CTTGCTGACCCAGAAATGATCAGCCAAATCAAGGAAACTATCCGTGCGAAGAAAGTGAAT
    GCAGAAGCAGGTCTGAAAGAAGTTACAGATATGTTTATCACTATCTTTGAAGGCATGGAA
    GACAACCCATACATGCAAGAACGCGCAGCGGATATCCGCGACGTGACAAAACGTGTATTG
    GCAAACCTTCTTGGTAAAAAATTGCCAAACCCAGCTTCTATCAATGAAGAAGTGATTGTG
    ATTGCGCATGACTTGACTCCTTCAGATACAGCTCAATTGGACAAAAACTTTGTAAAAGCT
    TTTGTAACCAACATTGGTGGACGTACAAGCCACTCAGCTATCATGGCACGTACACTTGAA
    ATTGCTGCTGTATTAGGTACAAACAACATCACTGAAATCGTTAAAGACGGTGACATCCTT
    GCTGTTAACGGGATCACTGGAGAAGTGATTATCAACCCAACAGATGAACAAGCGGCAGAA
    TTTAAAGCAGCTGGTGAAGCCTATGCGAAACAAAAAGCTGAATGGGCACTTTTGAAAGAT
    GCTCAAACAGTGACTGCTGACGGTAAACACTTCGAGTTGGCTGCCAATATTGGTACTCCA
    AAAGACGTTGAAGGTGTTAACAACAACGGTGCAGAAGCTGTTGGACTTTACCGTACAGAG
    TTCTTGTACATGGATTCTCAAGACTTCCCAACTGAAGATGAGCAGTATGAAGCATACAAG
    GCTGTTCTTGAAGGAATGAACGGTAAACCTGTTGTCGTTCGTACAATGGATATCGGTGGA
    GATAAGGAACTTCCTTACTTCGATATGCCTCACGAAATGAACCCATTCCTTGGATTCCGT
    GCTCTTCGTATCTCTATCTCTGAGACTGGAGATGCTATGTTCCGCACACAAATCCGTGCT
    CTTCTTCGTGCGTCTGTTCACGGTCAATTGCGTATCATGTTCCCAATGGTTGCGCTCTTG
    AAAGAATTCCGTGCAGCGAAAGCAGTCTTTGATGAAGAAAAAGCAAACCTTCTTGCTGAA
    GGTGTTGCAGTTGCGGATAACATTCAAGTTGGTATCATGATCGAGATTCCTGCAGCGGCT
    ATGCTTGCAGACCAATTTGCTAAAGAAGTTGACTTCTTCTCAATTGGTACAAATGACTTG
    ATCCAATATACAATGGCAGCAGACCGTATGAACGAACAAGTTTCATACCTTTACCAACCA
    TACAACCCATCAATCCTACGCTTGATTAACAATGTGATCAAAGCAGCTCACGCTGAAGGT
    AAATGGGCTGGTATGTGTGGTGAGATGGCTGGTGACCAACAAGCTGTTCCACTTCTTGTC
    GGAATGGGCTTGGATGAGTTCTCTATGTCAGCAACATCTGTACTTCGTACACGCAGCTTG
    ATGAAGAAACTCGACACAGCTAAGATGGAAGAGTACGCAAACCGTGCCCTTACAGAATGC
    TCAACAATGGAAGAAGTTCTTGAACTTCAAAAAGAATACGTTAATTTTGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1734

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL271_RS05950 [old locus tag: SPOH_1090 ]
  • symbol: PtsP
  • description: phosphoenolpyruvate--protein phosphotransferase
  • length: 577
  • theoretical pI: 4.34705
  • theoretical MW: 63295.9
  • GRAVY: -0.0937608

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.3.9?  ExPASy
    Phosphoenolpyruvate--protein phosphotransferase Phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine
  • TIGRFAM:
    phosphoenolpyruvate-protein phosphotransferase (TIGR01417; EC 2.7.3.9; HMM-score: 751.5)
    and 4 more
    Metabolism Energy metabolism Glycolysis/gluconeogenesis phosphoenolpyruvate synthase (TIGR01418; EC 2.7.9.2; HMM-score: 203.3)
    Metabolism Energy metabolism Other pyruvate, phosphate dikinase (TIGR01828; EC 2.7.9.1; HMM-score: 132.9)
    Genetic information processing Transcription RNA processing 16S rRNA processing protein RimM (TIGR02273; HMM-score: 14.6)
    6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase (TIGR03201; EC 1.1.1.-; HMM-score: 9.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PK_TIM (CL0151) PEP-utilizers_C; PEP-utilising enzyme, PEP-binding domain (PF02896; HMM-score: 424.4)
    and 3 more
    no clan defined PEP-utilisers_N; PEP-utilising enzyme, N-terminal (PF05524; HMM-score: 108.8)
    Leu-IlvD (CL0364) PEP-utilizers; PEP-utilising enzyme, mobile domain (PF00391; HMM-score: 78.8)
    B_Fructosidase (CL0143) Glyco_hydro_62; Glycosyl hydrolase family 62 (PF03664; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005992
    • TAT(Tat/SPI): 0.000642
    • LIPO(Sec/SPII): 0.000946
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000138135 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARLDAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAEAGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIVIAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGDILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAANIGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVRTMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRIMFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGEMAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEVLELQKEYVNFD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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