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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: EL271_RS07775 [old locus tag: SPOH_1446 ]
  • pan locus tag?: PNEUPAN002990000
  • symbol: EL271_RS07775
  • pan gene symbol?: oxlT
  • synonym:
  • product: L-lactate MFS transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL271_RS07775 [old locus tag: SPOH_1446 ]
  • symbol: EL271_RS07775
  • product: L-lactate MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 1443338..1444564
  • length: 1227
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018937 (1443338..1444564) NCBI
  • BioCyc: EL271_RS07775 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1414 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAATCTAATCGTTATATTATTGCCTTTACTGGGGTCATTTTACACTTAATGCTGGGT
    TCGACTTATGCTTGGAGTGTTTATCGTAACCCTATTATTGAAAAAACGGGATGGGATCAG
    GCTTCTGTTGCCTTTGCCTTTAGTCTAGCAATCTTTTGTTTGGGCTTATCGGCTGCATTT
    ATGGGGCGTTTGGTAGAAAAATTTGGTCCGAGAGTCATGGGGAGTCTATCTGCTTTTCTA
    TACGCAGGTGGAAATATCTTAACAGGATTTGCAATAGACCGTCAGGAACTGTGGTTGTTG
    TATCTCGCTTATGGCATTTTAGGTGGGCTTGGTTTGGGAGCAGGCTATATTACCCCTGTG
    TCAACGATTATAAAATGGTTTCCTGATAAACGTGGTCTCGCAACAGGTTTAGCGATTATG
    GGGTTTGGTTTTGCTTCTTTATTGACTAGTCCCATAGCGCAACATCTCATCGCAGGGGTA
    GGGCTTGTAGAAACTTTTTATATTTTAGGTGCAAGTTACTTTATTATCATGCTCCTAGCT
    TCACAATTCATTAAGCGTCCAAATGAGCAAGAGCTTGCAATTTTATCTGCTTCAGGGAAA
    GAAAAAACAGACTCTCTGACGCAAGGGATGACTGCAAATCAGGCTCTAAAAAGCAATCGG
    TTTTATATACTTTGGATTATTTTCTTTATCAACATAGCTTGTGGTTTAGGCTTAATTTCA
    GCGGCATCGCCAATGGCACAGGAGATGGCTGGCTTGTCTACAAGTCATGCAGCAGTAATG
    GTGGGCGTTTTAGGGATTTTCAATGGATTTGGTCGCTTGCTCTGGGCGAGCTTATCTGAC
    TATATCGGTCGCCCTCTAACCTTTAGTATATTACTGCTTGTTAATCTTTTCTTTTCTCTC
    TCACTTTGGCTCTTTACAGATTCCGTTTTATTTGTAGTCGCTATGTCTATTTTGATGACT
    TGCTATGGAGCTGGTTTTTCATTGATCCCAGCTTATCTCAGTGATATTTTTGGAACCAAG
    GAATTGGCCGCTCTGCATGGATATATTTTAACAGCTTGGGCAATGGCTGGTTTAGCGGGA
    CCTATTTTATTAGCAGAGACTTATAAAATGGCTCATTCGTACACACAAACCTTGTTCGTT
    TTTCTCATTTTATACAGTATCGCCTTGGCTTTGTCTTATTATCTAGGTCGTTCAATCAAA
    AAAGAAAGTCAAAAACCGCTTACATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1227

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL271_RS07775 [old locus tag: SPOH_1446 ]
  • symbol: EL271_RS07775
  • description: L-lactate MFS transporter
  • length: 408
  • theoretical pI: 9.37201
  • theoretical MW: 44330.2
  • GRAVY: 0.755147

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids oxalate/formate antiporter family transporter (TIGR00890; HMM-score: 224.4)
    oxalate/formate antiporter (TIGR04259; HMM-score: 186.7)
    and 8 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 55.3)
    Metabolism Transport and binding proteins Anions nitrite transporter (TIGR00886; HMM-score: 42.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids monocarboxylate transporter (TIGR00892; HMM-score: 41.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 33.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 28.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, sialate:H+ symporter (SHS) family (TIGR00891; HMM-score: 25.3)
    drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 20.7)
    multidrug resistance protein (TIGR00880; HMM-score: 9.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 129.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9988
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0011
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.183018
    • TAT(Tat/SPI): 0.002228
    • LIPO(Sec/SPII): 0.036292
  • predicted transmembrane helices (TMHMM): 12

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000841596 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKSNRYIIAFTGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVAFAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYLAYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGVGLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKSNRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWASLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLSDIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALSYYLGRSIKKESQKPLT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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