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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: EL334_RS00200 [old locus tag: ASP0581_00310 ]
  • pan locus tag?: PNEUPAN000649000
  • symbol: EL334_RS00200
  • pan gene symbol?: araT
  • synonym:
  • product: pyridoxal phosphate-dependent aminotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL334_RS00200 [old locus tag: ASP0581_00310 ]
  • symbol: EL334_RS00200
  • product: pyridoxal phosphate-dependent aminotransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 35716..36885
  • length: 1170
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP019192 (35716..36885) NCBI
  • BioCyc: EL334_RS00200 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0041 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGACTTAACTAAGCGCTTTAATAAACAGTTAGATAAGATTCAAGTTTCGTTGATTCGT
    CAGTTTGACCAGGCTATTTCGGAGATTCCTGGGGTCTTGCGTTTGACCTTGGGGGAACCT
    GATTTTACAACGCCAAATCATGTCAAGGAGGCGGCCAAGCGAGCGATTGATCAGAACCAA
    TCCTACTATACAGGGATGAGTGGTTTGCTGACTCTACGTCAGGCAGCCAGTGCCTTTGTT
    AAGGAAAAGTACCAACTGGACTATGCTCCTGAAAATGAAATCTTGGTTACAATTGGGGCG
    ACAGAGGCCTTATCTGCTACTTTGACAGCTATTTTAGAAGAGGGAGACAAGGTGCTCTTG
    CCAGCTCCTGCCTATCCAGGCTATGAACCGATTGTTAATCTAGTTGGGGCAGAGATTATC
    GAGATTGACACGACTGAAAATGGGTTTGTCTTGACTCCTGAGATGTTGGAAAAGGCCATT
    TTGGAGCAGGGAGACAAGCTCAAGGCGGTTATTCTCAACTATCCGGCTAATCCGACAGGA
    ATTACCTATAGTCGGGAGCAGTTGGAGGCCTTGGCAGCTGTTTTACGCAAGTACGAGATT
    TTCGTTGTCTGTGATGAGGTTTACTCAGAATTGACCTACACAGGCGAAGCCCATGTGTCT
    CTGGGAACTATGTTGAGAGACCAGGCTATTATTATCAATGGTTTGTCTAAATCGCATGCC
    ATGACAGGTTGGCGTTTGGGTCTAATTTTCGCTCCTGCGGCCTTCACAGCCCAATTGATC
    AAGAGTCATCAGTACTTGGTCACTGCAGCAAATACCATGGCGCAACATGCTGCGGTGGAA
    GCTTTGACAGCTGGTAAAAACGATGCGGAACCTATGAAGAAGGAATACATCCAGCGTCGG
    GATTATATCATCGAAAAGATGACCGCTCTTGGTTTTGAGATTATCAAACCAGACGGTGCC
    TTCTATATCTTTGCTAAGATTCCAGCGGGCTACAATCAAGACTCCTTTGCCTTTCTCAAG
    GATTTTGCTCAGAAGAAGGCCGTTGCCTTTATCCCTGGAGCTGCCTTTGGGCGTTACGGA
    GAAGGCTATGTTCGCTTGTCTTATGCAGCCAGCATGGAGACGATCAAAGAAGCCATGAAA
    CGGCTTGAGGAGTACATGAGAGAAGCATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1170

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL334_RS00200 [old locus tag: ASP0581_00310 ]
  • symbol: EL334_RS00200
  • description: pyridoxal phosphate-dependent aminotransferase
  • length: 389
  • theoretical pI: 5.07644
  • theoretical MW: 43140.3
  • GRAVY: -0.0724936

⊟Function[edit | edit source]

  • reaction:
    EC 2.6.1.-?  ExPASy
  • TIGRFAM:
    LL-diaminopimelate aminotransferase (TIGR03540; EC 2.6.1.83; HMM-score: 253.7)
    and 19 more
    succinyldiaminopimelate transaminase (TIGR03537; EC 2.6.1.17; HMM-score: 175.4)
    tyrosine/nicotianamine family aminotransferase (TIGR01265; HMM-score: 164.1)
    succinyldiaminopimelate transaminase (TIGR03538; EC 2.6.1.17; HMM-score: 144.3)
    succinyldiaminopimelate transaminase (TIGR03539; EC 2.6.1.17; HMM-score: 140.2)
    putative C-S lyase (TIGR04350; EC 4.4.-.-; HMM-score: 136.1)
    Metabolism Energy metabolism Amino acids and amines tyrosine aminotransferase (TIGR01264; EC 2.6.1.5; HMM-score: 135.8)
    Metabolism Amino acid biosynthesis Histidine family histidinol-phosphate transaminase (TIGR01141; EC 2.6.1.9; HMM-score: 127.7)
    Cellular processes Cellular processes Biosynthesis of natural products capreomycidine synthase (TIGR03947; HMM-score: 120.8)
    LL-diaminopimelate aminotransferase (TIGR03542; EC 2.6.1.83; HMM-score: 111.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin threonine-phosphate decarboxylase (TIGR01140; EC 4.1.1.81; HMM-score: 94.3)
    beta-methylarginine biosynthesis bifunctional aminotransferase (TIGR04544; EC 2.6.-.-; HMM-score: 81.6)
    enduracididine biosynthesis enzyme MppQ (TIGR04461; EC 2.-.-.-; HMM-score: 74.9)
    Metabolism Energy metabolism Amino acids and amines aspartate 4-decarboxylase (TIGR03801; EC 4.1.1.12; HMM-score: 45.2)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides TDP-4-keto-6-deoxy-D-glucose transaminase (TIGR02379; HMM-score: 18.7)
    2-aminoethylphosphonate aminotransferase (TIGR03301; EC 2.6.1.-; HMM-score: 17.2)
    Unknown function Enzymes of unknown specificity cysteine desulfurase family protein (TIGR01977; HMM-score: 15.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin adenosylmethionine-8-amino-7-oxononanoate transaminase (TIGR00508; EC 2.6.1.62; HMM-score: 13.8)
    aminotransferase, LLPSF_NHT_00031 family (TIGR04181; HMM-score: 11.7)
    enduracididine biosynthesis enzyme MppP (TIGR04462; EC 2.-.-.-; HMM-score: 11.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PLP_aminotran (CL0061) Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 207.7)
    and 7 more
    DegT_DnrJ_EryC1; DegT/DnrJ/EryC1/StrS aminotransferase family (PF01041; HMM-score: 26.5)
    Aminotran_5; Aminotransferase class-V (PF00266; HMM-score: 25.9)
    Beta_elim_lyase; Beta-eliminating lyase (PF01212; HMM-score: 19.7)
    Cys_Met_Meta_PP; Cys/Met metabolism PLP-dependent enzyme (PF01053; HMM-score: 17.1)
    Asp_aminotransf; Aspartate amino-transferase (PF12897; HMM-score: 15.2)
    no clan defined NIR_SIR_ferr; Nitrite/Sulfite reductase ferredoxin-like half domain (PF03460; HMM-score: 13.6)
    Cas_VVA1548; Putative CRISPR-associated protein (Cas_VVA1548) (PF09652; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9985
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0012
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008314
    • TAT(Tat/SPI): 0.000445
    • LIPO(Sec/SPII): 0.000617
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_023396089 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTTPNHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASAFVKEKYQLDYAPENEILVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIIEIDTTENGFVLTPEMLEKAILEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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