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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-MAY-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_1154 [new locus tag: HKM25_RS05650 ]
  • pan locus tag?: PNEUPAN002466000
  • symbol: recN
  • pan gene symbol?: recN
  • synonym:
  • product: DNA repair protein RecN

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_1154 [new locus tag: HKM25_RS05650 ]
  • symbol: recN
  • product: DNA repair protein RecN
  • replicon: chromosome
  • strand: -
  • coordinates: 1128314..1129858
  • length: 1545
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP053210 (1128314..1129858) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1062 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGAATATGATGTTGGGAGCTCGTGCGACGACAGATGTTATTCGTCATGGTGCACCAAAG
    GCAGAGATTGAGGGGCTTTTCTCAGTTGAGAATAGTCGTCTTTTACAGGAAATTTTTGAT
    GAGCAAGGTTTAGAATTAGGTGATGAAATTATCATCCGTCGGGAAATCTTGCAAAATGGT
    CGTAGTATCAGCCGTGTAAATGGTCAGATGGTTAATCTGTCTGTTTTGCGAGCTATTGGG
    CAACATCTTGTAGATATTCATGGTCAGCATGACCATGAGGAGTTAATGCGTCCCCAACTG
    CATATCCAGATGTTGGATGAATTTGGTGATGCCGCTTTTTGGGACTTGAAAGAAACCTAT
    CAAACGAGTTTTGATGCCTATCGGAAAATGCGCAAGCAGGTTCTGGAAGTCAAGAAAAAC
    CAACAGGAACACAAGGCACGTATCGAAATGTTGGAATTTCAAATGGCAGAGATTGAGGCA
    GCAAACTTGCAGGCTGGAGAAGACTTGGCTCTCAATCAAGAGCGAGATAAACTCCTCAAC
    CACAAAAATATTGCGGATACACTGACCAATGCCTACAGTATGTTGGACAATGAAGATTTT
    TCAAGTCTGGCCAATGTTCGTTCAGCTATGAATGACATGGAAAGTGTCGAAGAGTATGAT
    CCTGAATACCGTGAAATTTCAAGCTCTCTGTCTGAGACCTACTATGTTTTAGAAGACATT
    AGCAAACGTTTGGAAGCTATCATTGAGGACCTTGATTTTGATGGCAATCGCCTCATGCAG
    GTTGAGAATCGTTTGGACCTCCTTCATACTATTACTCGTAAGTATGGTGGGACTGTTGAT
    GATGTTTTGCTTTATTTTGCCAAGATTACGGAAGAATACAATCTCTTGACAGGCAATAAT
    CTTTCGTCTGAGGACATGGAAGCAGAGCTTAAGAAGTTGGAAGTCAATCTTGTCAATTTG
    GCAGGTCAACTTGCTTCTGCTCGTCATAATTTGGCTCAGCAACTCGAAGCTGAGATTAAA
    CAAGAACTGCAAGATCTTTATATGGAAAAAGCCCAGTTTCAGGTTCGTTTTAGTAAGGGA
    AAATTCAGTCGTGAGGGAAATGAAATGGTTGAGTTTTATATTTCAACCAACCCTGGAGAA
    GACTTTAAACCCTTGGTTAAGGTTGCTTCTGGAGGGGAATTATCTCGTCTCATGTTAGCC
    ATTAAGTCTGCCTTTTCACGTAAAGAAGGCAAGACTAGCATTGTCTTTGATGAAGTGGAT
    ACGGGAGTTTCAGGTCGTGTTGCTCAAGCTATTGCTCAGAAAATTCATAAAATTGGTCAG
    CATGGTCAGGTTTTGGCTATCTCCCATTTGCCACAAGTAATTGCGATTGCAGATTATCAA
    TTCTTTATTGAGAAGATTAGTAATGACCATTCAACGGTTTCGACTGTTCGTCTCTTGACG
    GTCGAAGAGCGAGTGGAGGAAGTTGCCAAGATGTTGGCAGGTGATGATGTGACAGAAGCA
    GCCCTGACGCAAGCCAGAGAATTGTTGAGAAACAGGGAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1545

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_1154 [new locus tag: HKM25_RS05650 ]
  • symbol: RecN
  • description: DNA repair protein RecN
  • length: 514
  • theoretical pI: 4.68273
  • theoretical MW: 58456.7
  • GRAVY: -0.415564

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair protein RecN (TIGR00634; HMM-score: 473.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    P-loop_NTPase (CL0023) SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 38.9)
    and 6 more
    no clan defined Holin_BhlA; BhlA holin family (PF10960; HMM-score: 12.2)
    HEF_HK; HEF_HK domain (PF19191; HMM-score: 11.5)
    FlxA; FlxA-like protein (PF14282; HMM-score: 11)
    DUF2408; Protein of unknown function (DUF2408) (PF10303; HMM-score: 10.9)
    Snapin_Pallidin; Snapin/Pallidin (PF14712; HMM-score: 7.6)
    H2TH (CL0303) NFACT_N; NFACT N-terminal and middle domains (PF05833; HMM-score: 6.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005591
    • TAT(Tat/SPI): 0.000677
    • LIPO(Sec/SPII): 0.000387
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QJS36862 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNMMLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDKLLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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