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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-MAY-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_1814 [new locus tag: HKM25_RS08865 ]
  • pan locus tag?: PNEUPAN003222000
  • symbol: HKM25_1814
  • pan gene symbol?: gspA_2
  • synonym:
  • product: glycosyl transferase 2 family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_1814 [new locus tag: HKM25_RS08865 ]
  • symbol: HKM25_1814
  • product: glycosyl transferase 2 family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1738037..1740082
  • length: 2046
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP053210 (1738037..1740082) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    GTGGAAAACTATCTGAGGAAGTGCCTAGATAGTATTATTACTCAAACATATAAAAATATT
    GAGATTGTTGTCGTTAATGATGGTTCTACGGATGCTTCAGGTGAAATTTGTAAAGAATTT
    GCAGAAATGGATCACCGAATTACCTATATAGAACAAGAAAATGCTGGGCTGTCAGCTGCA
    CGAAACACCGGTCTGAATAATATGTCCGGAAATTATGTGACCTTTGTGGATTCAGATGAT
    TGGATTGAGTTAGATTATGTAGAAACCCTATATAAAAAAATAACAGAATATCAAGCTGAT
    ATTGCAGTTGGGAATTACTATTCTTTCAACGAAAGTGAAGGAATGTTCTACTTTCATATA
    TCAGGAGACTCCTATTATGAGAAGGTATATGACAATGTTTCCATCTTTGAGAATTTGTAT
    GAAACTCAAGAAATGAGGAGTTTCGCTTTGATATCTGCTTGGGGTAAACTCTATAAGGCG
    AGATTGTTTGAGCAGTTGCGCTTTGACATGGGTAAATTAGGAGAAGATGGTTACCTCAAT
    CAAAAGGTATATTTATTATCAGAAAAGGTAATTTATTTAAATAAAAGTCTTTATGCTTAT
    CGTATTAGAAAAGGTAGTCTATCAAGAATTTGGACAGAAAAGTGGATGCATGCATTGGTT
    GATGCCATGTCCGAACGCATTACGCTATTAGCTAATATGGGTTACCCTTTAGAAAAGCAT
    TTGGCGATTTATCGTCAAATGTTGGAATTCAGTCTCTCCAACGGTCAAGCTAGCGGTTTA
    TCTGACACAGCAACATATAAAGAGTTTGAAATGAAACAAAGGCTTTTAAATCAGCTATTG
    AGACAAGAGTCAAGTGAAAAGAAAGCCATTGTCCTAGCGGCGAATTATGCCTATGTAGAC
    CAAGTTTTAACGACAATCAAGTCTATCTGTTACCACAATCGCTCGCTTCGTTTTTATTTG
    ATTCATAGCGATTTTCCAAATGAATGGATCAAACAATTAAATAAGCGATTAGAGAAGTTT
    GACTCAGAAATTATTAATTGTCGGGTAACTTCTGAGCAAATTTCATGTTATAAATCGGAT
    ATTAGTTACACAGTCTTTTTACGCTATTTCATAGCTGATTTCGTGCAAGAAGACAAGGCC
    CTCTACTTGGACTGTGATTTACTTGTAACGAAAAATCTCGATGACTTGTTTGTTACAGAC
    TTACAAGGTTATCCTTTGGCTGCTGTTAGAGATTTCGGGGGAAGAGCCTATTTCGGTCAA
    GAAATCTTTAATGCCGGTGTTCTCTTGGTAAACAATGCTTTTTGGAAAAAAGAGAATATG
    ACCCAAAAATTAATTGATTTGACTAATGAATGGCATAATAAGGTGGAACAGGCTGATCAA
    AGTATTTTGAATATGCTTTTTGAACATAAATGGTTGGAATTGGACTTTGATTATAATCAT
    ATTGTCATTCATAAACAGTTCGCTGATTATCAATTGCCTGAGGGTCAGGATTATCCTGCT
    ATTATTCACTATCTTTCTCATCGGAAACCGTGGAAAGATTTGGCGGCCCAAACCTATCGT
    GAAGTTTGGTGGTACTATCATGGGCTTGAATGGACAGAATTGGGACAAAACCATCATTTA
    CATCCATTACAAAGATCTCACATATATCCAATAAAGGAACCTTTCACTTGTCTAATCTAT
    ACTGCCTCAGACCATATTGAACAAATTGAGACATTGGTTCAATCCTTGCCTGATATTCAG
    TTTAAGATAGCAGCTAGAGTAATAGTTAGTGATCGATTGGCTCAGATGACAATTTATCCA
    AACGTGACTATATTTAACGGAATTCACTATTTGGTAGATGTCGATAATGAATTGGTAGAA
    ACCAGTCAAGTACTTTTAGATATTAATCATGGTGAAAAAACAGAGGAAATTATCAATCAA
    TTTGCAAGACTTGGAAAAACTATTTTGTCCTTTGAAAATACCAAAACCTATGAAGTAGGT
    CAGGAGGCATATGCTGTTGACCAAGTTCAAGCAATGATTGAGAAATTGAGAGAAATAAGC
    AAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2046

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_1814 [new locus tag: HKM25_RS08865 ]
  • symbol: HKM25_1814
  • description: glycosyl transferase 2 family protein
  • length: 681
  • theoretical pI: 5.02942
  • theoretical MW: 79791.9
  • GRAVY: -0.336564

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein modification and repair accessory Sec system glycosyltransferase GtfB (TIGR02919; EC 2.4.1.-; HMM-score: 65.9)
    and 9 more
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 51.7)
    chitooligosaccharide synthase NodC (TIGR04242; EC 2.4.1.-; HMM-score: 41)
    mycofactocin system glycosyltransferase (TIGR03965; HMM-score: 40.9)
    colanic acid biosynthesis glycosyltransferase WcaA (TIGR04017; EC 2.4.-.-; HMM-score: 29.6)
    Unknown function Enzymes of unknown specificity transferase 2, rSAM/selenodomain-associated (TIGR04283; EC 2.-.-.-; HMM-score: 25.4)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 21.3)
    hopene-associated glycosyltransferase HpnB (TIGR03469; HMM-score: 20.6)
    colanic acid biosynthesis glycosyltransferase WcaE (TIGR04009; EC 2.4.-.-; HMM-score: 19)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides rhamnosyltransferase (TIGR01556; EC 2.4.1.-; HMM-score: 17.5)
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    GT-A (CL0110) Glyco_transf_8; Glycosyl transferase family 8 (PF01501; HMM-score: 137.1)
    Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 117.2)
    and 3 more
    Glyco_tranf_2_2; Glycosyltransferase like family 2 (PF10111; HMM-score: 47.4)
    Glyco_tranf_2_3; Glycosyltransferase like family 2 (PF13641; HMM-score: 35.8)
    Glyco_tranf_2_4; Glycosyl transferase family 2 (PF13704; HMM-score: 16.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9163
    • Cytoplasmic Membrane Score: 0.0472
    • Cell wall & surface Score: 0.0021
    • Extracellular Score: 0.0344
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017324
    • TAT(Tat/SPI): 0.000231
    • LIPO(Sec/SPII): 0.000826
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QJS37519 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MENYLRKCLDSIITQTYKNIEIVVVNDGSTDASGEICKEFAEMDHRITYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIELDYVETLYKKITEYQADIAVGNYYSFNESEGMFYFHISGDSYYEKVYDNVSIFENLYETQEMRSFALISAWGKLYKARLFEQLRFDMGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYRIRKGSLSRIWTEKWMHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLSNGQASGLSDTATYKEFEMKQRLLNQLLRQESSEKKAIVLAANYAYVDQVLTTIKSICYHNRSLRFYLIHSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDKALYLDCDLLVTKNLDDLFVTDLQGYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKKENMTQKLIDLTNEWHNKVEQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEGQDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKEPFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYLVDVDNELVETSQVLLDINHGEKTEEIINQFARLGKTILSFENTKTYEVGQEAYAVDQVQAMIEKLREISK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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