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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS05710 [old locus tag: HKM25_1166 ]
  • pan locus tag?: PNEUPAN002484000
  • symbol: HKM25_RS05710
  • pan gene symbol?: nirC
  • synonym:
  • product: formate/nitrite transporter family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS05710 [old locus tag: HKM25_1166 ]
  • symbol: HKM25_RS05710
  • product: formate/nitrite transporter family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1138705..1139502
  • length: 798
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (1138705..1139502) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1075 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGGTTTCTTCAGAATTTATCTCAAAGATTGAATTTGCTTGCAATAAGAAAGAAAGTCTT
    TATAGTCAAAGCAAATTTAAGTATGCGATTCGTTCGATGTTCGCAGGTGCATTTTTAACC
    TTCAGTACTGCTGCAGGTGCAGTTGGGGCTGACTTGATTAATAAAATTGCACCAGGTAGT
    GGACGCTTCCTCTTTCCATTCGTTTTTGCTTGGGGCTTGGCCTACATTGTTTTTTTGAAT
    GCCGAGTTGGTCACTTCAAACATGATGTTCTTGACTGCTGGTAGTTTCTTAAAAAAAATC
    TCTTGGAGAAAAACAGCTGAGATTTTACTATACTGTACCTTGTTCAACCTTATCGGAGCC
    TTGATAGCAGGGTGGGGCTTTGCTCATTCGGCAGCCTATGCGAATCTGACACACGATAGT
    TTCATCTCAGGTGTTGTTGGGATGAAGTTAGGCCGCTCAAATGAATTGGTCTTGCTTGAG
    GCGATTTTGGCAAATATTTTCGTAAATATTGCGATTCTGTCATTTATTTTGGTCAAAGAT
    GGTGGTGCCAAACTTTGGCTTGTGTTGTCAGCTATTTACATGTTTGTATTCTTAACAAAC
    GAGCACATTGCGGCGAACTTTGCTTCTTTCGCGATTGTGAAATTCAGTGTTGCTGCGGAT
    TCAATTGCCAACTTCGGTGTTGGAAATATGCTTCGCCACTGGGGTGTGACTTTCATCGGA
    AACTTTATCGGAGGAGGCCTCTTGCTGGGTCTTCCATATGCCTTCCTCAATAAAAACGAA
    GATACTTATGTAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    798

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS05710 [old locus tag: HKM25_1166 ]
  • symbol: HKM25_RS05710
  • description: formate/nitrite transporter family protein
  • length: 265
  • theoretical pI: 9.27977
  • theoretical MW: 28867.7
  • GRAVY: 0.719623

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions formate/nitrite transporter (TIGR00790; HMM-score: 99.1)
    and 2 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids formate transporter FocA (TIGR04060; HMM-score: 70.2)
    cobalt transporter subunit CbtB (proposed) (TIGR02459; HMM-score: 13.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Aquaporin-like (CL0716) Form_Nir_trans; Formate/nitrite transporter (PF01226; HMM-score: 137.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.290717
    • TAT(Tat/SPI): 0.118985
    • LIPO(Sec/SPII): 0.015859
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_054362641 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTAAGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVGMKLGRSNELVLLEAILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSIANFGVGNMLRHWGVTFIGNFIGGGLLLGLPYAFLNKNEDTYVD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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