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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS10020 [old locus tag: HKM25_2053 ]
  • pan locus tag?: PNEUPAN003545000
  • symbol: HKM25_RS10020
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS10020 [old locus tag: HKM25_2053 ]
  • symbol: HKM25_RS10020
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1959260..1959643
  • length: 384
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (1959260..1959643) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAATACCATAGAGCGGACTAGGCGGCTGGTTAAAGGCTGCGCAACACACTGTTTTGAG
    GTTGTAGATAGAACTGACGAAGTCAGCTCAAAGCATGTTTTTGAGGTTGCAGATGAAACT
    GACGAAGTCAGCTCAAAACATGTTTTTGAGGTTGTGGATGAAACTGACGAAGTCAGCTCA
    AAACATGTTTTTGAGGTTGTGGATGAAACTGACGAAGTCAGCTCAAAACATGTTTTTGAG
    GTTGTGGATGAAACTGACGAAGTCAGCTCAAAACATGTTTTTGAGGTTGTGGATGAAACT
    GACGAAGTCAGCTCAAAACATGTTTTTGAGGTTGTGGATGAAACTGACGAAGTCAGTAAC
    CATACATACGGTAAGGCGACGTGA
    60
    120
    180
    240
    300
    360
    384

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS10020 [old locus tag: HKM25_2053 ]
  • symbol: HKM25_RS10020
  • description: hypothetical protein
  • length: 127
  • theoretical pI: 4.15598
  • theoretical MW: 14422.5
  • GRAVY: -0.56378

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General ROK family protein (putative glucokinase) (TIGR00744; HMM-score: 21)
    and 3 more
    Metabolism Transport and binding proteins Anions phosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 11.9)
    Signal transduction Regulatory functions Other phosphate transport system regulatory protein PhoU (TIGR02135; HMM-score: 11.9)
    EXLDI protein (TIGR04342; HMM-score: 10.3)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    no clan defined Ribosomal_L11; Ribosomal protein L11, RNA binding domain (PF00298; HMM-score: 15.8)
    HTH (CL0123) YdaS_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT (PF15943; HMM-score: 15.6)
    no clan defined DUF1810; Protein of unknown function (DUF1810) (PF08837; HMM-score: 15.2)
    TPR (CL0020) DUF5071; Domain of unknown function (DUF5071) (PF16804; HMM-score: 13.8)
    HTH (CL0123) DUF3895; Protein of unknown function (DUF3895) (PF13034; HMM-score: 12.8)
    and 7 more
    Phage_TACs (CL0567) Phage_TAC_8; Phage tail assembly chaperone protein Gp14 ()A118 (PF10666; HMM-score: 11.7)
    no clan defined CMV_1a_C; Cucumber mosaic virus 1a protein C terminal (PF12503; HMM-score: 10.7)
    PH (CL0266) PH; PH domain (PF00169; HMM-score: 9.9)
    PDZ-like (CL0466) PDZ_4; PDZ domain (PF17816; HMM-score: 9.7)
    no clan defined DUF3638; Protein of unknown function (DUF3638) (PF12340; HMM-score: 7.6)
    PDDEXK (CL0236) tRNA_int_endo; tRNA intron endonuclease, catalytic C-terminal domain (PF01974; HMM-score: 7.3)
    no clan defined Orthopox_F6; Orthopoxvirus F6 protein (PF06601; HMM-score: 7.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006271
    • TAT(Tat/SPI): 0.002139
    • LIPO(Sec/SPII): 0.00107
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001092044 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVADETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDEVSNHTYGKAT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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