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serotype 4
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serotype 2
D39V
serotype 2
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serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
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ATCC 700669
serotype 23F
BM6001
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BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 28-AUG-2013

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_10824 [new locus tag: HMPREF0837_RS03985 ]
  • pan locus tag?: PNEUPAN001397000
  • symbol: mesE
  • pan gene symbol?: blpB
  • synonym:
  • product: bacteriocin secretion accessory protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_10824 [new locus tag: HMPREF0837_RS03985 ]
  • symbol: mesE
  • product: bacteriocin secretion accessory protein
  • replicon: chromosome
  • strand: -
  • coordinates: 758171..759532
  • length: 1362
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAATCCTAATCTTTTTAGAAGCGTCGAGTTTTATCAGAGACGTTACCATAACTATGCG
    ACAGTATTAATCATACCTCTTTCATTATTATTTACTTTCATCTTGATTTTCTCCCTTGTT
    GCCACAAAAGAAATTACTGTTACTTCCCAAGGGGAAATCACCCCTACAAGTGTCATTGCA
    TCTATTCAGTCGACCAGTGATAATCCTATCCTTGCTAATCATTTAGTGGCAAATCAAGTA
    GTTGAGAAAGGTGACTTACTCATCAAATACTCTGAAACAATGGAAGAGAGTCAGAAAACT
    GCCTTAGAAACTCAATTACAAAGACTTGAGAAGCAAAAAGAAGGACTTGGAATCTTGAAA
    CAAAGCTTAGAAAAAGCGACTGATCTTTTTTCTAGCGAGGATGAGTTTGGCTACCATAAT
    ACTTTTATGAATTTTACTAAACAATCCCATGATATTGAACTGGGTATCTCAAAGACTAAC
    ACTGAAGTTTCAAATCAAGCTAATCTTACCAATAGCAGTTCATCAGCCATCGAACAAGAA
    ATTACAAAAGTTCAACAACAAATTGGAGAATATCAAGAGCTGAGAGATACTATCGTAAAT
    AAAAGAGCTCGCTTACCAACTGGCAATCCGCACCAGTCAATTTTAAATCGTTATCTTATA
    GCCTCTCAAGAACAAACACAAGGAACGGCAGAGGAGCCATTTTTATCTCAAATTAATCAA
    AGTATTGCAGGTCTGGAATCATCTATCGCAAGCCTCAAAATTCAGCAAGCTGGTATCGGA
    AGTGTAGCAACTTATGATAATAGTTTAGCAACCAAAATTGAAGTACTCCGCACTCAGTTT
    TTACAAACAGCCTCACAGCAACAACTAACCGTGGAGAATCAATTAACAGAATTAAAAGTA
    CAACTAGATCAAGCAACGCAGCGCTTAGGAAACAATACCTTAACCGCTCCAAGTAAAGGT
    ATCGTTCATCTGAACAGCGAATTTGAAGGTAAAAATAGAATTCCAACTGGTACAGAAATT
    GCTCAAATATTCCCTGTCATCACAGATACAAGAGAAGTACTAATCACTTACTACGTATCT
    TCTGACTATCTACCTCTACTAGATAAAGGACAAACTGTAAGATTAAAACTGGAGAAGATT
    GGAAATCACGGCACCACCATCATCGGCCAACTTCAGACAATTGATCAAACTCCTACCAGA
    ACAGAGCAAGGTAATCTCTTTAAATTAACCGCTCTTGCAAAACTATCTAATGAGGATAGT
    AAACTCATCCAATATGGCTTACAAGGTCGCGTCACTAGTGTAACTGCAAAGAAAACATAT
    TTTGATTATTTCAAAGATAAAATTTTAACCCATTCTGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1362

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_10824 [new locus tag: HMPREF0837_RS03985 ]
  • symbol: MesE
  • description: bacteriocin secretion accessory protein
  • length: 453
  • theoretical pI: 5.91527
  • theoretical MW: 50643.7
  • GRAVY: -0.364459

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Other bacteriocin secretion accessory protein (TIGR01000; HMM-score: 405.1)
    and 5 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion membrane fusion protein, HlyD family (TIGR01843; HMM-score: 68)
    Metabolism Transport and binding proteins Unknown substrate efflux transporter, RND family, MFP subunit (TIGR01730; HMM-score: 39)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system secretion protein (TIGR03794; HMM-score: 24.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system secretion protein (TIGR03794; HMM-score: 24.1)
    Metabolism Transport and binding proteins Other efflux pump membrane protein (TIGR00998; HMM-score: 16)
  • TheSEED  :
    • Competence-stimulating peptide ABC transporter permease protein ComB
    DNA Metabolism DNA uptake, competence Competence in Streptococci  Competence-stimulating peptide ABC transporter permease protein ComB
  • PFAM:
    Hybrid (CL0105) HlyD_3; HlyD family secretion protein (PF13437; HMM-score: 61.1)
    and 2 more
    no clan defined Osmo_CC; Osmosensory transporter coiled coil (PF08946; HMM-score: 11.8)
    DUF5082; Domain of unknown function (DUF5082) (PF16888; HMM-score: 9.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0005
    • Cytoplasmic Membrane Score: 0.9801
    • Cell wall & surface Score: 0.0052
    • Extracellular Score: 0.0142
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.061295
    • TAT(Tat/SPI): 0.001948
    • LIPO(Sec/SPII): 0.013588
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADI69052 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKEITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTALETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTNTEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDTIVNKRARLPTGNPHQSILNRYLIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVLRTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRIPTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQTIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILTHSD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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