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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_RS02135 [old locus tag: HMPREF0837_10430 ]
  • pan locus tag?: PNEUPAN000798000
  • symbol: rnjA
  • pan gene symbol?: rnjA
  • synonym:
  • product: ribonuclease J1

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_RS02135 [old locus tag: HMPREF0837_10430 ]
  • symbol: rnjA
  • product: ribonuclease J1
  • replicon: chromosome
  • strand: -
  • coordinates: 395711..397390
  • length: 1680
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_014251 (395711..397390) NCBI
  • BioCyc: HMPREF0837_RS02135 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0130 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGGCCTACACTCTTAAACCTGAAGAAGTCGGCGTTTTTGCCATCGGTGGTCTAGGAGAA
    ATCGGGAAAAACACTTACGGAATTGAATACCAAGACGAGATTATCATCGTCGATGCTGGG
    ATTAAATTCCCAGAAGATGACTTGCTTGGTATCGACTATGTCATTCCTGACTACTCTTAC
    ATCGTGGACAATATCGACCGCGTCAAGGCTGTTTTAATCACACACGGACACGAGGACCAC
    ATTGGTGGGATTCCGTTCCTACTCAAGCAAGCAAATGTCCCTATCTACGCTGGACCGCTT
    GCCTTGGCTTTGATCCGTGGGAAACTCGAAGAACACGGCCTCTTGCGCAACGCCAAACTT
    TACGAAATCAACCACAACACCGAGTTGACCTTTAAAAATCTCAAGGCAACTTTCTTTAGA
    ACGACTCACTCTATTCCAGAGCCTTTGGGGATTGTCATTCATACTCCTCAAGGGAAAATC
    GTCTGTACGGGTGACTTTAAGTTCGACTTTACTCCAGTTGGAGAACCTGCGGACTTGCAT
    CGTATGGCTGCGCTTGGTGAAGAAGGCGTGCTCTGTCTCCTGTCTGACTCGACAAATGCG
    GAAGTACCAACCTTTACCAACTCTGAAAAAGTCGTTGGTCAGTCCATTATGAAGATTATC
    CAAGGTATTGAAGGACGTATCATCTTTGCATCCTTTGCCTCAAATATCTTCCGTCTCCAG
    CAGGCAACAGAAGCTGCTGTTAAGACTGGACGCAAGATTGCGGTCTTTGGTCGTTCTATG
    GAAAAGGCCATTGTCAACGGAATCGATCTTGGCTACATCAAAGCTCCTAAGGGAACCTTT
    ATCGAGCCAAATGAAATCAAAGATTATCCTGCAGGAGAAGTTCTTATCCTCTGTACAGGT
    AGTCAGGGTGAGCCTATGGCAGCCCTCTCTCGTATCGCCAACGGAACCCACCGTCAAGTA
    CAATTACAACCAGGTGATACCGTTATCTTCTCTTCTAGTCCCATCCCTGGAAACACTACT
    AGCGTCAACAAGCTGATTAACATCATTTCTGAAGCTGGTGTCGAAGTTATCCACGGTAAA
    GTGAACAATATCCATACATCTGGACACGGTGGCCAGCAAGAGCAAAAACTCATGCTCCGC
    TTGATTAAGCCAAAATACTTCATGCCTGTCCACGGTGAATACCGCATGCAAAAAGTCCAC
    GCTGGACTAGCAGTGGATACTGGTGTTGAGAAGGACAATATCTTTATCATGAGCAATGGC
    GATGTGCTTGCCCTTACTGCTGACTCAGCTCGTATCGCAGGTCATTTCAACGCCCAAGAT
    ATCTATGTCGATGGAAATCGTATCGGTGAAATTGGCGCAGCTGTCCTCAAAGATCGTCGC
    GATCTATCTGAAGACGGTGTCGTTCTAGCAGTCGCAACTGTTGACTTCAAATCGCAGATG
    ATTCTGTCTGGCCCAGATATCCTCAGCCGAGGCTTTGTCTACATGAGAGAGTCTGGAGAC
    TTGATTCGCCAAAGCCAGCGTATCCTCTTCAATGCCATTCGTATCGCACTGAAAAATAAG
    GATGCTAGCGTGCAATCTGTCAATGGTGCCATTGTCAACGCTATTCGCCCCTTCCTCTAT
    GAAAATACCGAACGTGAACCGATCATCATCCCGATGATCCTCACACCAGATGAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_RS02135 [old locus tag: HMPREF0837_10430 ]
  • symbol: RnjA
  • description: ribonuclease J1
  • length: 559
  • theoretical pI: 5.881
  • theoretical MW: 61061.7
  • GRAVY: -0.00894454

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Transcription Degradation of RNA beta-CASP ribonuclease, RNase J family (TIGR00649; EC 3.1.-.-; HMM-score: 653.1)
    and 6 more
    arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein (TIGR03675; HMM-score: 40.7)
    Cellular processes Cellular processes Detoxification hydroxyacylglutathione hydrolase (TIGR03413; EC 3.1.2.6; HMM-score: 23)
    Genetic information processing Transcription RNA processing ribonuclease Z (TIGR02651; EC 3.1.26.11; HMM-score: 20.6)
    putative exonuclease, DNA ligase-associated (TIGR04122; HMM-score: 17.3)
    Cellular processes Cellular processes DNA transformation DNA internalization-related competence protein ComEC/Rec2 (TIGR00361; HMM-score: 15.1)
    phosphonate metabolism protein PhnP (TIGR03307; HMM-score: 11.7)
  • TheSEED: see HMPREF0837_10430
  • PFAM:
    no clan defined RNase_J_C; Ribonuclease J C-terminal domain (PF17770; HMM-score: 92.3)
    and 6 more
    Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 62.7)
    RMMBL_DRMBL (CL0398) RMMBL; Zn-dependent metallo-hydrolase RNA specificity domain (PF07521; HMM-score: 49.1)
    Metallo-HOrase (CL0381) Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 45.6)
    Lactamase_B_6; Metallo-beta-lactamase superfamily domain (PF16661; HMM-score: 14.8)
    Lactamase_B_3; Beta-lactamase superfamily domain (PF13483; HMM-score: 14.4)
    SH3 (CL0010) DUF4453; Domain of unknown function (DUF4453) (PF14627; HMM-score: 13.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9128
    • Cytoplasmic Membrane Score: 0.0267
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0601
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005979
    • TAT(Tat/SPI): 0.000139
    • LIPO(Sec/SPII): 0.000969
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000331983 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFPEDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLALALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKIVCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMKIIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAPKGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSPIPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHGEYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGEIGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRILFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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