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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_RS02775 [old locus tag: HMPREF0837_10568 ]
  • pan locus tag?: PNEUPAN000985000
  • symbol: HMPREF0837_RS02775
  • pan gene symbol?: talC
  • synonym:
  • product: fructose-6-phosphate aldolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_RS02775 [old locus tag: HMPREF0837_10568 ]
  • symbol: HMPREF0837_RS02775
  • product: fructose-6-phosphate aldolase
  • replicon: chromosome
  • strand: +
  • coordinates: 498954..499622
  • length: 669
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014251 (498954..499622) NCBI
  • BioCyc: HMPREF0837_RS02775 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0236 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGAATTTATGCTTGACACATTAAATTTAGATGAGATTAAAAAGTGGTCTGAAATTTTG
    CCGCTAGCTGGGGTAACTTCAAATCCCACTATTGCAAAAAGAGAGGGTTCTATTAATTTT
    TTTGAACGAATCAAAGATGTAAGAGAATTGATTGGCTCTACACCCTCTATTCATGTTCAG
    GTGATTTCTCAAGATTTTGAAGGCATCTTAAAGGATGCTCATGAAATTCGAAGACAAGCA
    GGAGATGATATATTTATCAAAGTACCTGTTACTCCAGCTGGATTACGTGCAATAAAGGTG
    CTAAAAAAAGAGGGCTACCATATCACTGCAACAGCTATTTATACAGTTATTCAGGGATTA
    TTAGCTATCGAAGCAGGAGCGGATTACCTAGCTCCATATTATAATAGAATGGAAAATCTG
    AACATTGATTCAAATTCTGTCATTCGTCAATTAGCTCTTGCTATTGATAGACAGAACTCT
    CCTAGTAAGATTTTAGCTGCATCCTTTAAAAATGTAGCACAAGTAAATAATGCTTTAGCT
    GCAGGTGCGCATGCTGTTACAGCAGGAGCAGATGTTTTTGAATCAGCTTTCGCCATGCCA
    TCTATCCAAAAGGCGGTTGATGATTTTTCTGACGATTGGTTTGTTACTCAAAATAGTCGT
    TCCATTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    669

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_RS02775 [old locus tag: HMPREF0837_10568 ]
  • symbol: HMPREF0837_RS02775
  • description: fructose-6-phosphate aldolase
  • length: 222
  • theoretical pI: 5.32042
  • theoretical MW: 24390.6
  • GRAVY: -0.0117117

⊟Function[edit | edit source]

  • reaction:
    EC 4.1.2.-?  ExPASy
  • TIGRFAM:
    Metabolism Energy metabolism Pentose phosphate pathway fructose-6-phosphate aldolase (TIGR00875; EC 4.1.2.-; HMM-score: 178.5)
    and 5 more
    Metabolism Energy metabolism Pentose phosphate pathway transaldolase (TIGR02134; EC 2.2.1.2; HMM-score: 50.9)
    Metabolism Energy metabolism Pentose phosphate pathway transaldolase (TIGR00874; EC 2.2.1.2; HMM-score: 28.8)
    Metabolism Energy metabolism Pentose phosphate pathway transaldolase (TIGR00876; EC 2.2.1.2; HMM-score: 15.3)
    predicted phospho-2-dehydro-3-deoxyheptonate aldolase (TIGR01949; EC 4.2.1.-; HMM-score: 12.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Lipoate lipoyl synthase (TIGR00510; EC 2.8.1.8; HMM-score: 11.8)
  • TheSEED: see HMPREF0837_10568
  • PFAM:
    TIM_barrel (CL0036) TAL_FSA; Transaldolase/Fructose-6-phosphate aldolase (PF00923; HMM-score: 138.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9773
    • Cytoplasmic Membrane Score: 0.006
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0166
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018051
    • TAT(Tat/SPI): 0.001293
    • LIPO(Sec/SPII): 0.001326
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000395427 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERIKDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLKKEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNSPSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQNSRSI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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