From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-AUG-2013

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_01374 [new locus tag: HMPREF1038_RS06715 ]
  • pan locus tag?: PNEUPAN002662000
  • symbol: potD
  • pan gene symbol?: potD
  • synonym:
  • product: spermidine/putrescine ABC transporter spermidine/putrescine-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_01374 [new locus tag: HMPREF1038_RS06715 ]
  • symbol: potD
  • product: spermidine/putrescine ABC transporter spermidine/putrescine-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1271380..1272450
  • length: 1071
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAAAAAAATCTATTCATTTTTAGCAGGAATTGCAGCGATTATCCTTGTCTTGTGGGGA
    ATTGCGACTCATTTAGATAGTAAAATCAATAGTCGAGATAGTCAAAAATTGGTTATCTAT
    AACTGGGGAGACTATATCGATCCTGAACTCTTGACTCAGTTTACAGAAGAAACAGGAATT
    CAAGTTCAGTACGAGACTTTTGACTCCAACGAAGCCATGTACACTAAGATAAAGCAGGGT
    GGAACGACCTACGATATTGCCATTCCAAGTGAATACATGATTAACAAGATGAAGGACGAA
    GACCTCTTGGTTCCGCTTGATTATTCAAAAATTGAAGGAATCGAAAATATCGGACCAGAG
    TTTCTCAACCAGTCCTTTGACCCAGGTAATAAATTCTCCATCCCTTACTTCTGGGGAACC
    TTAGGAATTGTCTACAACGAAACCATGGTAGATGAAGCGCCTGAGCATTGGGATGACCTT
    TGGAAGCCGGAGTATAAGAATTCTATCATGCTCTTTGATGGGGCGCGTGAGGTGCTGGGA
    CTAGGACTCAATTCCCTCGGCTACAGCCTCAACTCCAAGGATCTGCAGCAGTTGGAAGAG
    ACAGTGGATAAGCTCTACAAACTGACTCCAAATATCAAGGCTATCGTTGCGGACGAGATG
    AAGGGCTATATGATTCAGAATAATGTTGCAATCGGCGTGACCTTCTCTGGTGAAGCCAGC
    CAAATGTTAGAAAAAAATGAAAATCTACGTTATGTGGTACCGACAGAGGCCAGCAATCTT
    TGGTTTGACAATATGGTCATTCCCAAAACAGTTAAAAACCAAAACTCAGCCTATGCCTTT
    ATCAACTTTATGTTGAAACCTGAAAATGCTCTCCAAAATGCGGAGTATGTCGGCTATTCA
    ACACCAAACCTACCAGCGAAGGAATTGCTCCCAGAGGAAACAAAGGAAGATAAGGCCTTC
    TATCCCGATGTTGAAACCATGAAACACCTAGAAGTTTATGAGAAATTTGACCATAAATGG
    ACAGGGAAATATAGCGACCTCTTCCTACAGTTTAAAATGTATCGGAAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1071

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF1038_01374 [new locus tag: HMPREF1038_RS06715 ]
  • symbol: PotD
  • description: spermidine/putrescine ABC transporter spermidine/putrescine-binding protein
  • length: 356
  • theoretical pI: 4.42947
  • theoretical MW: 41010.4
  • GRAVY: -0.389888

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein (TIGR03261; HMM-score: 38)
    and 4 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids carbohydrate ABC transporter substrate-binding protein, CPR_0540 family (TIGR03850; HMM-score: 20.6)
    Metabolism Transport and binding proteins Other ABC transporter periplasmic binding protein, thiB subfamily (TIGR01254; HMM-score: 19.9)
    2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein (TIGR03227; HMM-score: 19.2)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, periplasmic molybdate-binding protein (TIGR01256; HMM-score: 18.6)
  • TheSEED  :
    • ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1)
    Amino Acids and Derivatives Arginine; urea cycle, polyamines Polyamine Metabolism  ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1)
  • PFAM:
    PBP (CL0177) SBP_bac_8; Bacterial extracellular solute-binding protein (PF13416; HMM-score: 127.2)
    SBP_bac_6; Bacterial extracellular solute-binding protein (PF13343; HMM-score: 119.2)
    and 4 more
    SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 57.1)
    SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 42.6)
    Lipoprotein_8; Hypothetical lipoprotein (MG045 family) (PF02030; HMM-score: 39.9)
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0003
    • Cytoplasmic Membrane Score: 0.7899
    • Cell wall & surface Score: 0.0043
    • Extracellular Score: 0.2055
  • SignalP: Signal peptide SP(Sec/SPI) length 31 aa
    • SP(Sec/SPI): 0.750821
    • TAT(Tat/SPI): 0.002052
    • LIPO(Sec/SPII): 0.079858
    • Cleavage Site: CS pos: 31-32. INS-RD. Pr: 0.3655
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFS43406 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGDYIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDLLVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDLWKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVADEMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNSAYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYEKFDHKWTGKYSDLFLQFKMYRK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=HMPREF1038_01374&oldid=78656"