PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 02-AUG-2013

⊟Summary

• organism: Streptococcus pneumoniae gamPNI0373
• locus tag: HMPREF1038_01497 [new locus tag: HMPREF1038_RS07315 ]
• pan locus tag^?: PNEUPAN002839000
• symbol: HMPREF1038_01497
• pan gene symbol^?: IS1239
• synonym:
• product: putative IS1239, transposase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: HMPREF1038_01497 [new locus tag: HMPREF1038_RS07315 ]
• symbol: HMPREF1038_01497
• product: putative IS1239, transposase
• replicon: chromosome
• strand: -
• coordinates: 1375814..1376821
• length: 1008
• essential: unknown

⊟Accession numbers

• Location: CP001845 (1375814..1376821) NCBI
• BioCyc: see HMPREF1038_RS07315
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_1342 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  
  ATGCAAGACAATTATACTACAAAAGGTAAACATTTGACAATCGATAGCCGTCGCTTAATC
  GAAAGATGGAAAAAAGAAGGAAAATCAAATAGAGAAGTTGCCTCTCTACTTGGAAAAGCT
  CCTCAAACTATCCACACTGAAATCAAGCGTGGGACAGTCCGACAATGTCTTGGAAAAGGG
  CGCTTCAAAGAGGTTTATTCTGCCGACTACGCTCAACAGTCTTATGAAAACAATCGCAAG
  CGCTCGGTCAAGAAATCAAGCTTGACCAAGGAACTAAAGGAAAAGATTCTCCACTATCAT
  AACCAAAAATTTTCGCCTGAAATGATGGTGATGGCTAAAGGGGTTAACGTGGGAATTTCA
  ACCATTTACTATTGGATTCATCATGGAAAATTGGGGTTAAGCAAGCAGGATTTGCCTTAC
  CCTAGAAAAGGAAAAGCGCTTAAGAAACAGGCCAGCACCAACTTTAAACCTGCTGGTCAA
  TCCATCGCACAGCGGCCTGAAGCTATCAATCTTCGCTTGGAGAATGGGCATTATGAGATT
  GATACGGTTCTACTTACGAGAGCGAAAAACTACTGCTTGCTTGTCTTGACGGATCGAAAG
  AGTAGACATCAGATCATCCGATTGATTCCAAATAAAAGTGCTGAGGTGGTCAATCAGGCT
  CTAAAACTCATCTTAAAACAACACAAGATTCTTTCCATCACGGCAGATAATGGAACGGAA
  TTCAATCGCTTGTCTGATGTATTTTCTGAGGAGCACATTTATTATGCGCACCCCTATGCC
  TCTTGGGAAAGGGGAACTAATGAGAATCACAACAGGTTCATTCGTAGATGGTTACCTAAG
  GGAACCAAGAAAATGACTCCCAAAGAAGTCGCATTCATCGAAAAGTGGATTAACAACTAT
  CCTAAAAAATGCTTGGACTACAAGTCACCCAGAGAAGACTTCTTGATGGCTAACTTGAAC
  TTGAAATTTAGCAAAATGGAAATAATTTTTATTAAACGCTTCCAATAG
  60
  120
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  360
  420
  480
  540
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  660
  720
  780
  840
  900
  960
  1008
  

⊟Protein

⊟General

• locus tag: HMPREF1038_01497 [new locus tag: HMPREF1038_RS07315 ]
• symbol: HMPREF1038_01497
• description: putative IS1239, transposase
• length: 335
• theoretical pI: 10.6166
• theoretical MW: 39222.1
• GRAVY: -0.758209

⊟Function

• TIGRFAM:
  Unknown function General DNA binding domain, excisionase family (TIGR01764; HMM-score: 14.9)
  RNA polymerase sigma-70 factor, Bacteroides expansion family 1 (TIGR02985; HMM-score: 14.3)
  RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 13.5)
  and 1 more
  RNA polymerase sigma-70 factor, TIGR02960 family (TIGR02960; HMM-score: 11.9)
• TheSEED  :
  • Mobile element protein
• PFAM:
  HTH (CL0123) HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 65.2)
  and 6 more
  HTH_17; Helix-turn-helix domain (PF12728; HMM-score: 22.4)
  RNase_H (CL0219) rve; Integrase core domain (PF00665; HMM-score: 21.2)
  HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 16.3)
  Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 15.7)
  PKinase (CL0016) PK_Tyr_Ser-Thr; Protein tyrosine and serine/threonine kinase (PF07714; HMM-score: 14.3)
  no clan defined DnaB_2; Replication initiation and membrane attachment (PF07261; HMM-score: 14.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.007883
  • TAT(Tat/SPI): 0.00275
  • LIPO(Sec/SPII): 0.001842
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: AFS43526 NCBI
• UniProt:

⊟Protein sequence

• MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTIHTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQSIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFLMANLNLKFSKMEIIFIKRFQ

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1342 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications