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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_RS03120 [old locus tag: HMPREF1038_00631 ]
  • pan locus tag?: PNEUPAN001537000
  • symbol: HMPREF1038_RS03120
  • pan gene symbol?: glnH2
  • synonym:
  • product: transporter substrate-binding domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_RS03120 [old locus tag: HMPREF1038_00631 ]
  • symbol: HMPREF1038_RS03120
  • product: transporter substrate-binding domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 571208..572002
  • length: 795
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018630 (571208..572002) NCBI
  • BioCyc: HMPREF1038_RS03120 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0530 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAAAAAAAATTCTTTTTATCAGCATTATTGATTAGCCTTTTCGGCCTTGCTGCTGCC
    AAACCAGTCCAGGCTGATACTAGTATCGCAGACATTCAAAAAAGAGGCGAACTGGTTGTC
    GGTGTCAAACAAGACGTTCCCAATTTTGGTTACAAAGATCCCAAGACCGGTACTTATTCT
    GGTATCGAAACCGACTTGGCCAAGATGGTAGCTGATGAACTCAAGGTCAAGATTCGCTAT
    GTGCCGGTTACAGCACAAACCCGCGGCCCCCTTCTAGACAATGAACAGGTCGATATGGAT
    ATCGCGACCTTTACCATCACGGACGAACGCAAAAAACTCTACAACTTTACCAGTCCCTAC
    TACACAGACGCTTCTGGATTTTTGGTCAATAAATCTGCCAAAATCAAAAAGATTGAGGAC
    CTAAACGGCAAAACCATCGGAGTCGCCCAAGGTTCTATCACCCAACGCCTAATTACTGAA
    CTGGGTAAAAAGAAAGGTCTGAAGTTTAAATTCGTCGAACTTGGTTCCTACCCAGAATTG
    ATTACTTCCCTTCACGCTCATCGTATCGATGCCTTTTCCGTTGACCGCTCTATTCTGTCT
    GGCTACACTAGTAAACGCACAGAACTACTAGATGATAGTTTCAAGCCATCTGACTACGGT
    ATTGTTACCAAGAAATCAAATACAGAGCTCAACGACTATCTTGATAACTTGGTTACTAAA
    TGGAGCAAGGATGGTAGTTTGCAGAAACTTTATGACCGTTACAAGCTCAAACCATCTAGC
    CATACTGCAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    795

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF1038_RS03120 [old locus tag: HMPREF1038_00631 ]
  • symbol: HMPREF1038_RS03120
  • description: transporter substrate-binding domain-containing protein
  • length: 264
  • theoretical pI: 9.8102
  • theoretical MW: 29481.6
  • GRAVY: -0.396591

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 148.4)
    and 9 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 44.9)
    extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 31.7)
    Metabolism Transport and binding proteins Other ABC transporter, substrate-binding protein, aliphatic sulfonates family (TIGR01728; HMM-score: 29)
    Metabolism Transport and binding proteins Unknown substrate TRAP transporter solute receptor, TAXI family (TIGR02122; HMM-score: 27.4)
    Metabolism Transport and binding proteins Anions phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein (TIGR01098; HMM-score: 21.2)
    quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein (TIGR03871; HMM-score: 20.3)
    Metabolism Energy metabolism Other methanol oxidation system protein MoxJ (TIGR03870; HMM-score: 17.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids methanol oxidation system protein MoxJ (TIGR03870; HMM-score: 17.1)
    taurine ABC transporter, periplasmic binding protein (TIGR01729; HMM-score: 13.5)
  • TheSEED: see HMPREF1038_00631
  • PFAM:
    PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 170)
    and 5 more
    NMT1; NMT1/THI5 like (PF09084; HMM-score: 38.7)
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 27.5)
    Phosphonate-bd; ABC transporter, phosphonate, periplasmic substrate-binding protein (PF12974; HMM-score: 27.1)
    YhfZ_C; YhfZ C-terminal domain (PF14503; HMM-score: 25.2)
    NMT1_3; NMT1-like family (PF16868; HMM-score: 16.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 25 aa
    • SP(Sec/SPI): 0.994929
    • TAT(Tat/SPI): 0.000863
    • LIPO(Sec/SPII): 0.003787
    • Cleavage Site: CS pos: 25-26. VQA-DT. Pr: 0.9653
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000726169 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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