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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-NOV-2024

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_RS12870 [old locus tag: HMPREF1038_01738 ]
  • pan locus tag?: PNEUPAN001385000
  • symbol: HMPREF1038_RS12870
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_RS12870 [old locus tag: HMPREF1038_01738 ]
  • symbol: HMPREF1038_RS12870
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1602509..1602856
  • length: 348
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_018630 (1602509..1602856) NCBI
  • BioCyc: HMPREF1038_RS12870 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    GTGTTTGAGGTTGTAGATAAAACTGACGAAGTCAGCTCAAAACACTGTTTTGAGGTTGCA
    GATAGAACTGACGAAGTCAGCTTAAAACACTGTTTTGAGGTTGCAGATAGAACTGACGAA
    GTCAGCTTAAAACACTGTTTTGAGGTTGCAGATAGAACTGACGAAGTCAGCTTAAAACAC
    TGTTTTGAGGTTGCAGATAGAACTGACGAAGTCAGCTTAAAACACTGTTTTGAGGTTGTG
    GATAGAACTGACGAAGTCAGTAACCATACCTACGGCAAGGTGAAGCTGACGTGGTTTGAA
    GAGATTTTCGAAGAGTATCATACGAAAAAGCCCTGTTCCTCAAGATGA
    60
    120
    180
    240
    300
    348

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: HMPREF1038_RS12870 [old locus tag: HMPREF1038_01738 ]
  • symbol: HMPREF1038_RS12870
  • description: hypothetical protein
  • length: 115
  • theoretical pI: 4.68114
  • theoretical MW: 13495.9
  • GRAVY: -0.66

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General ROK family protein (putative glucokinase) (TIGR00744; HMM-score: 15.2)
  • TheSEED: see HMPREF1038_01738
  • PFAM:
    no clan defined Ribosomal_L11; Ribosomal protein L11, RNA binding domain (PF00298; HMM-score: 23.9)
    DNA_ligase_IV; DNA ligase IV (PF11411; HMM-score: 23.4)
    and 5 more
    SPFH (CL0433) MVP_shoulder; Shoulder domain (PF11978; HMM-score: 16.7)
    no clan defined Corazonin; Pro-corazonin (PF17308; HMM-score: 13.1)
    DUF3874; Domain of unknonw function from B. Theta Gene description (DUF3874) (PF12990; HMM-score: 12.4)
    SAB; SAB domain (PF04382; HMM-score: 11.2)
    GCK; GCK domain (PF07802; HMM-score: 11.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5037
    • Cytoplasmic Membrane Score: 0.0009
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.4944
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004949
    • TAT(Tat/SPI): 0.000417
    • LIPO(Sec/SPII): 0.001444
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000464396 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MFEVVDKTDEVSSKHCFEVADRTDEVSLKHCFEVADRTDEVSLKHCFEVADRTDEVSLKHCFEVADRTDEVSLKHCFEVVDRTDEVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]