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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-FEB-2016

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV104
  • locus tag: INV104_09780 [new locus tag: INV104_RS05670 ]
  • pan locus tag?: PNEUPAN000036000
  • symbol: INV104_09780
  • pan gene symbol?:
  • synonym:
  • product: Integrase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: INV104_09780 [new locus tag: INV104_RS05670 ]
  • symbol: INV104_09780
  • product: Integrase
  • replicon: chromosome
  • strand: -
  • coordinates: 1071007..1072170
  • length: 1164
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: FQ312030 (1071007..1072170) NCBI
  • BioCyc: see INV104_RS05670
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAATATCATAGAGAAAATTAAAAAGAATGGCCAAAGAGTTTATTATGCTAGTGTTTAT
    CTAGGCGTTGACCAACTAACGGGCAAAAAAGCCCGTACAACTGTTACAGCAACCACTAAA
    AAGGGCGTTAAAGTAAAAGCGCGTGATGCGATCAATACTTTTGCTGCTAATGGCTATACA
    GTTAAAGATAAGCCGACAATTACAACATACAATGAGCTTGTAAAAGTTTGGTGGGATAGT
    TACAAGAATACAGTTAAGCCAAATACTCGCCAATCCATGGATGGATTGGTTAGAGTGCAT
    TTATTGCCTGTATTTGGCGATTACAAGCTATCTAAACTTACTACGCCTATTCTTCAACAG
    CAAGTAAACAAATGGGCTGACAAGGCAAATAAAGGCGAAAAAGGGGCATTTGCTAACTAC
    TCCTTGCTCCATAACATGAATAAGCGTATTTTGAAATATGGCGTAGCTATCCAGGTAATA
    CAATACAACCCAGCTAATGATGTAATCGTTCCACGCAAACAGCAGAAAGAAAAGGCTGCT
    GTCAAATACTTAGACAACAAAGAATTAAAACAGTTTCTTGATTATTTAGACACTCTGAAT
    CAATCAAATTATGAGAACTTATTTGATGTTGTCCTGTATAAGACTTTATTGGCCACTGGT
    TGCCGTATTAGTGAGGCTCTAGCTCTTGAATGGTCTGATATTGACCTAGAAAGCGGTGTT
    ATCAGCATCAATAAGACACTAAACCGCTATCAGGAAATAAATTCACCTAAATCAAGCGCT
    GGTTATCGTGATATACCAATAGACAAAGCCACATTACTTTTACTGAAACAATACAAAAAC
    CGTCAACAAATTCAGTCTTGGAAATTAGGCCGATCTGAAACAGTTGTATTCTCTGTATTT
    ACGGAGAAATATGCTTATGCTTGTAACTTACGCAAACGCCTAAATAAGCATTTTGATGCT
    GCTGGAGTAACTAACGTATCATTTCATGGTTTCCGCCATACACATACTACTATGATGCTC
    TATGCTCAGGCTAGCCCGAAAGATGTTCAGTATAGATTAGGCCACTCTAATTTAATGATC
    ACTGAAAATACTTACTGGCATACTAACCAAGAGAATGCAAAAAAAGCCGTCTCAAATTAT
    GAAACAGCTATCAGCAATTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1164

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: INV104_09780 [new locus tag: INV104_RS05670 ]
  • symbol: INV104_09780
  • description: Integrase
  • length: 387
  • theoretical pI: 10.1978
  • theoretical MW: 44291.4
  • GRAVY: -0.518346

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 73.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 70)
    and 2 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 34)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 34)
  • TheSEED  :
    • Integrase/recombinase, phage associated
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 102.4)
    and 3 more
    l-integrase_N (CL0469) Phage_int_SAM_3; Phage integrase, N-terminal SAM-like domain (PF14659; HMM-score: 55.8)
    no clan defined GCFC; GC-rich sequence DNA-binding factor-like protein (PF07842; HMM-score: 14.1)
    E-set (CL0159) RET_CLD1; RET Cadherin like domain 1 (PF17756; HMM-score: 13.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9522
    • Cytoplasmic Membrane Score: 0.0034
    • Cell wall & surface Score: 0.0125
    • Extracellular Score: 0.0319
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.085561
    • TAT(Tat/SPI): 0.004566
    • LIPO(Sec/SPII): 0.008989
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW36660 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVKVKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLLPVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVIQYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLATGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLKQYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHTHTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]