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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-OCT-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BVJ1JL
  • locus tag: JN057_01779 [new locus tag: JN057_RS08690 ]
  • pan locus tag?: PNEUPAN003316000
  • symbol: JN057_01779
  • pan gene symbol?: pkn1
  • synonym:
  • product: Formylglycine-generating enzyme

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JN057_01779 [new locus tag: JN057_RS08690 ]
  • symbol: JN057_01779
  • product: Formylglycine-generating enzyme
  • replicon: chromosome
  • strand: -
  • coordinates: 1691801..1692247
  • length: 447
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP071871 (1691801..1692247) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGTCTTTACCGACTGAAGCACAGTGGGAATATGCTGCTAGAGGAGGAAGACAATCTGAA
    TATCCTTGGGGAGATACTCTTTTAGAAGGTGGATATTATCATGCCAATACTTGGCAAGGA
    AGATTTCCTTATGAAAATACTGTCTCAGATGGATTTATAGGAACGGCTCCTGTCTATGAA
    TTTTTACCTAATGATTTTGGTCTATATCAAATGATTGGGAATGTTTGGGAATGGTGTCGC
    AATCCGAGATATACCTTATTAGCTAGTTTTAATGAAGATGACTATGAGTTGCCAAAATAT
    GGGATACAAGATGAGGAGTATGCTATCAGAGGAGGTTCCTTTTTATGTCATTGTTCTTAT
    TGTAATCGATACCGAGTAGCTGCTAGAAATGGATGTATTTCTACTTCCACTAGTAGCCAT
    CTAGGTTTTAGATGTTTGAAAGAATAG
    60
    120
    180
    240
    300
    360
    420
    447

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JN057_01779 [new locus tag: JN057_RS08690 ]
  • symbol: JN057_01779
  • description: Formylglycine-generating enzyme
  • length: 148
  • theoretical pI: 4.74155
  • theoretical MW: 17066.8
  • GRAVY: -0.590541

⊟Function[edit | edit source]

  • reaction:
    EC 1.8.3.7?  ExPASy
    Formylglycine-generating enzyme A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O
  • TIGRFAM:
    gliding motility-associated lipoprotein GldK (TIGR03529; HMM-score: 87.3)
    and 6 more
    gliding motility-associated lipoprotein GldK (TIGR03525; HMM-score: 57)
    gliding motility-associated lipoprotein GldJ (TIGR03530; HMM-score: 35.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs ergothioneine biosynthesis protein EgtB (TIGR03440; HMM-score: 32.4)
    gliding motility-associated lipoprotein GldJ (TIGR03524; HMM-score: 27.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs 5-histidylcysteine sulfoxide synthase (TIGR04344; HMM-score: 25.2)
    fibrobacter succinogenes paralogous family TIGR02171 (TIGR02171; HMM-score: 18.7)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    C_Lectin (CL0056) FGE-sulfatase; Sulfatase-modifying factor enzyme 1 (PF03781; HMM-score: 131.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0857
    • Cytoplasmic Membrane Score: 0.2113
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.7022
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.082067
    • TAT(Tat/SPI): 0.000653
    • LIPO(Sec/SPII): 0.005817
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QTE33355 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSLPTEAQWEYAARGGRQSEYPWGDTLLEGGYYHANTWQGRFPYENTVSDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRYTLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLGFRCLKE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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