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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-OCT-2023

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BVJ1JL
  • locus tag: JN057_02117 [new locus tag: JN057_RS10325 ]
  • pan locus tag?: PNEUPAN003760000
  • symbol: JN057_02117
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JN057_02117 [new locus tag: JN057_RS10325 ]
  • symbol: JN057_02117
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1977387..1978319
  • length: 933
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP071871 (1977387..1978319) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGAGAACAAATTTGTAGAATTTATCGAAAACAATAAAAAAGTAATCATTTCATCAGTT
    GCAGTTGGTGTTGTATTGATATTAGGGTTTGGATGGTATTCATATAACCAACAACAAGCA
    GAACAACAAGCAAAAATTGTACAATTAGAAAAAGATAGCAAATCAGACAAAGAACAAGTT
    GATAAACTATTTGAATCATTTGATGCATCTTCAGATGAATCTATTTCTAAATTAAAAGAA
    CTATCTGAAACTTCACTTAAAACCGATGCAGGTAAAGACTATCTTAATAACAAAGTCAAA
    GAATCATCTAAAGCAATTGTAGATTTTCATTTGCAAAAAGGTTTGGCTTATGATGTTAAA
    GATTCTGATGAGAAGTTTAAAGATAAAGCAACTCTTGAAACAAATGTGAAAGAAATTACA
    AAACAAATTGATTTTATCAAAAAAGTTGATGAAACTTTTAAACAAGAGAATTTGGAAGAA
    ACTCTTAAATCTCTAAATGATCTTGTTGATAAATATCAAAAACAAATCGAACTTTTGAAG
    AAAGAAGAAGAAAAAGCTGCTGAAAAAGCAAAGGAATCTTCTAGTCAAAGTAATTCTTCT
    GGTAGTGCTTCTAATGAGTCTTATAATGGATCTTCCAATTCAAATGTAGATTATAGTTCA
    TCTGAACAAACTAATGGATATTCAAATAATTATGGCGGTCAAGATTATTCTGGTTCTGGA
    AATAGTTCAACAAATGGTGGATCATCAGAACAATATTCATCTAGAAATTCAAACATTGGA
    GCAAATAATGGCTATACAGAATATAGAAGCATTGATGCTAGTGGACATGTAAGAGATACT
    TATCATAATCGGAGTAATGGAGATGTGTTTGACGAAAATGGGAATTACCTTGGAAACTTG
    GGGGGCGGCATTGCAGAACCTCCACAACGCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    933

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JN057_02117 [new locus tag: JN057_RS10325 ]
  • symbol: JN057_02117
  • description: hypothetical protein
  • length: 310
  • theoretical pI: 4.596
  • theoretical MW: 34390.9
  • GRAVY: -1.00806

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines mitochondrial precursor proteins import receptor (TIGR00990; HMM-score: 21.2)
    and 4 more
    early transcribed membrane protein (ETRAMP) family (TIGR01495; HMM-score: 15.9)
    phage lysis regulatory protein, LysB family (TIGR03495; HMM-score: 13.8)
    SH3 domain protein (TIGR04211; HMM-score: 4)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides oligosaccharide repeat unit polymerase (TIGR04370; HMM-score: 3.1)
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    no clan defined SlyX; SlyX (PF04102; HMM-score: 21.1)
    TPR (CL0020) TPR_21; Tetratricopeptide repeat-like domain (PF09976; HMM-score: 21.1)
    and 17 more
    no clan defined ETRAMP; Malarial early transcribed membrane protein (ETRAMP) (PF09716; HMM-score: 14.6)
    Scaffold; Scaffold domain (PF20142; HMM-score: 14.4)
    TMP_2; Prophage tail length tape measure protein (PF06791; HMM-score: 12.8)
    DUF4307; Domain of unknown function (DUF4307) (PF14155; HMM-score: 12.6)
    FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 12.4)
    no clan defined MRPL52; Mitoribosomal protein mL52 (PF18699; HMM-score: 11.6)
    LapA_dom; Lipopolysaccharide assembly protein A domain (PF06305; HMM-score: 11.2)
    Histone_HNS; H-NS histone family (PF00816; HMM-score: 10.9)
    Traffic (CL0147) Sec20; Sec20 (PF03908; HMM-score: 8.1)
    no clan defined DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 8)
    DUF6080; Family of unknown function (DUF6080) (PF19558; HMM-score: 7.7)
    DinB (CL0310) DUF1993; Domain of unknown function (DUF1993) (PF09351; HMM-score: 7.4)
    no clan defined DUF4446; Protein of unknown function (DUF4446) (PF14584; HMM-score: 7.2)
    Ax_dynein_light; Axonemal dynein light chain (PF10211; HMM-score: 6.9)
    YebO; YebO-like protein (PF13974; HMM-score: 6.5)
    LMBR1; LMBR1-like membrane protein (PF04791; HMM-score: 6.2)
    SHR3_chaperone; ER membrane protein SH3 (PF08229; HMM-score: 5.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.295
    • Cell wall & surface Score: 0.0559
    • Extracellular Score: 0.649
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.141188
    • TAT(Tat/SPI): 0.001872
    • LIPO(Sec/SPII): 0.005925
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QTE33626 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MENKFVEFIENNKKVIISSVAVGVVLILGFGWYSYNQQQAEQQAKIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKESSKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEETLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSGSASNESYNGSSNSNVDYSSSEQTNGYSNNYGGQDYSGSGNSSTNGGSSEQYSSRNSNIGANNGYTEYRSIDASGHVRDTYHNRSNGDVFDENGNYLGNLGGGIAEPPQR

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]