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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-APR-2025

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BVJ1JL
  • locus tag: JN057_RS00810 [old locus tag: JN057_00163 ]
  • pan locus tag?: PNEUPAN000758000
  • symbol: JN057_RS00810
  • pan gene symbol?: scaA
  • synonym:
  • product: lactococcin 972 family bacteriocin

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JN057_RS00810 [old locus tag: JN057_00163 ]
  • symbol: JN057_RS00810
  • product: lactococcin 972 family bacteriocin
  • replicon: chromosome
  • strand: +
  • coordinates: 139096..139380
  • length: 285
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_CP071871 (139096..139380) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0106 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGAGAAAATTAGTTAAAATTGGTGTTGCATCTTTAATGGTATGTAGTATACTTGCTTCT
    ACAAGTGTTTTGGCAGTATGGGTTGATGGTGGTCAATGGAACTATGGAGTAGGATGGTCA
    GGAAATTTTGGTTATTCTGATTATTTACATTCTACTCGCTCTCATACAGCAACTGTTAAA
    GATGGAAATAAATTCTCTAAGGATCGTGCAGAAGCTGAGGCATGGGCTCGGGCTTCAATC
    TTCAAATTCCCACCAACGGGAATGGAATATTTCTATGGATTTTAA
    60
    120
    180
    240
    285

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JN057_RS00810 [old locus tag: JN057_00163 ]
  • symbol: JN057_RS00810
  • description: lactococcin 972 family bacteriocin
  • length: 94
  • theoretical pI: 9.46872
  • theoretical MW: 10423.8
  • GRAVY: -0.0829787

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance bacteriocin, lactococcin 972 family (TIGR01653; HMM-score: 76.1)
    and 1 more
    probable ammonium transporter, marine subtype (TIGR03644; HMM-score: 11.7)
  • TheSEED: data available for D39, Hungary19A-6
  • PFAM:
    no clan defined Lactococcin_972; Bacteriocin (Lactococcin_972) (PF09683; HMM-score: 83.5)
    and 1 more
    LolA_LolB (CL0048) LolA_2; Outer membrane lipoprotein carrier protein LolA (PF16584; HMM-score: 11.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.9999
  • SignalP: Signal peptide SP(Sec/SPI) length 25 aa
    • SP(Sec/SPI): 0.976158
    • TAT(Tat/SPI): 0.001025
    • LIPO(Sec/SPII): 0.012725
    • Cleavage Site: CS pos: 25-26. VLA-VW. Pr: 0.8764
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001230167 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]