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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BVJ1JL
  • locus tag: JN057_RS06875 [old locus tag: JN057_01421 ]
  • pan locus tag?: PNEUPAN002677000
  • symbol: JN057_RS06875
  • pan gene symbol?: rsmF
  • synonym:
  • product: RsmF rRNA methyltransferase first C-terminal domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JN057_RS06875 [old locus tag: JN057_01421 ]
  • symbol: JN057_RS06875
  • product: RsmF rRNA methyltransferase first C-terminal domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1350594..1351898
  • length: 1305
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP071871 (1350594..1351898) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1233 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAAATTTCCAGAAGGATTTGTTGAAAAATATAAAGAAATACTAGGAGATGAGGCAAGA
    GATTTTCTTGCCTCTTTTGAGGAGGAAGCGGTTTCGGCCTTTCGGGTCAATCCCTTAAAA
    GAAGAGCAACTTTCCTTTTCTGATGCCATTACTCAAACCCCTTGGGGCCACTATGGGAAG
    GTTTCAGGGAAATCGCCTGAGCATGCTACAGGTTTAGTTTATTCGCAAGAACCTGCTGCT
    CAAATGGTGGCTCAAGTAGCCCAACCCAGTCCTGGTATGAAGGTCTTGGACTTGGCTGCT
    GCACCGGGGGGCAAATCAACTCAACTGGCAGCCTATCTAGCAGGGGAGGGGCTACTTGTT
    TCCAATGAAATTTCAAGCAAACGGGCTAAGATTTTGGTTGAAAACATGGAGCGTTTTGGA
    GCGACAAATGTCGTGGTGACCAATGAATCTGCCGACCGCTTGGTCAAGGTCTTTAAAGGC
    TATTTTGACTTAATCGTTCTTGATGCCCCTTGCTCTGGTGAAGGAATGTTTCGTAAGCAA
    CCTGATGCTATGGACTATTGGAGCTTAGATTATCCGAGTCAATGTGCTAGCTTGCAAAGA
    GAAATTCTGGAGGATGCAGTGACCATGTTAGCTGAAGGTGGTCGTCTGGTTTATTCGACC
    TGTACCTGGGCACCCGAGGAAAACGAAGAGATTGTCAATTGGTTGCTGGAAGAGTATGAT
    TTTGACTTGTTGCCAGTAGAGCATATCAATGGAATGGTAGCTGGTATTGACCTGCCAGAA
    ACGGCTCGGATGTACCCTCATCAGTTTAAGGGAGAGGGTCAGTTTGTTGCCCATCTACAG
    TTTAAGGGTAACAATCCAGCTCCTAAATTTAAGGCAAGTAAGAGTAACCTCAGCCGTGAA
    CAAGTTGCCTTGTGGCAGGAATTTGCCCAAAACCATTTGAAGGTCAATCTACCGGGTATC
    TTGCAGATTTTTGGAGACCAGCTTTATCTCTTGCCAGAACTTTTGCCAGATTTAGGGAAG
    CTCAAGATTGCTCGCAATGGACTGCATCTGGGTACTTTTAAGAAGAAACGCTTTGAGCCC
    AGTTTCGCTCTTGGTTTAGCCTTGAAACCGAGTCAGGTCGAACAGTCGGTTGAAATTGGC
    CAAGAAGAGTTTGTCAAGTATGCGGCTGGAGAAACCGTTCAGCTGGCAGAAAGTCTGCCA
    AATGGTTGGTACCAAGTTTTGGTTAAAGGCAATGGCTTGGGCTTTGCAAAGGTTACTGGA
    AATGTTTTGAAAAATTATTTTCCAAAAGGCCTCAGATTCAAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1305

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JN057_RS06875 [old locus tag: JN057_01421 ]
  • symbol: JN057_RS06875
  • description: RsmF rRNA methyltransferase first C-terminal domain-containing protein
  • length: 434
  • theoretical pI: 5.12578
  • theoretical MW: 48119.6
  • GRAVY: -0.235484

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification NOL1/NOP2/sun family putative RNA methylase (TIGR00446; EC 2.1.1.-; HMM-score: 195.2)
    and 5 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification 16S rRNA (cytosine(967)-C(5))-methyltransferase (TIGR00563; EC 2.1.1.176; HMM-score: 138.9)
    Genetic information processing Protein synthesis tRNA and rRNA base modification ribosomal RNA large subunit methyltransferase J (TIGR00438; EC 2.1.1.166; HMM-score: 22.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit (TIGR02469; EC 2.1.1.132; HMM-score: 17)
    methyltransferase, FxLD system (TIGR04364; HMM-score: 14.2)
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific (TIGR03533; EC 2.1.1.-; HMM-score: 13.2)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) Methyltr_RsmB-F; 16S rRNA methyltransferase RsmB/F (PF01189; HMM-score: 144.3)
    and 7 more
    Pre-PUA (CL0668) RsmF_methylt_CI; RsmF rRNA methyltransferase first C-terminal domain (PF17126; HMM-score: 76.2)
    NADP_Rossmann (CL0063) Methyltr_RsmF_N; N-terminal domain of 16S rRNA methyltransferase RsmF (PF17125; HMM-score: 61.7)
    PUA (CL0178) Methyltranf_PUA; RNA-binding PUA-like domain of methyltransferase RsmF (PF13636; HMM-score: 60)
    NADP_Rossmann (CL0063) Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 26.6)
    FtsJ; FtsJ-like methyltransferase (PF01728; HMM-score: 24.3)
    TRM; N2,N2-dimethylguanosine tRNA methyltransferase (PF02005; HMM-score: 12.8)
    PCMT; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) (PF01135; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.994
    • Cytoplasmic Membrane Score: 0.0017
    • Cell wall & surface Score: 0.0004
    • Extracellular Score: 0.0039
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.012523
    • TAT(Tat/SPI): 0.003091
    • LIPO(Sec/SPII): 0.001
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000671535 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQLSFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAPGGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKGYFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVYSTCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFVAHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPELLPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGETVQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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