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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS03045 [old locus tag: MDRSPN_00564 ]
  • pan locus tag?: PNEUPAN001650000
  • symbol: MDRSPN_RS03045
  • pan gene symbol?: cupA
  • synonym:
  • product: cupredoxin domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS03045 [old locus tag: MDRSPN_00564 ]
  • symbol: MDRSPN_RS03045
  • product: cupredoxin domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 581895..582266
  • length: 372
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (581895..582266) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0634 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTTAAATAGCATTGTAACCATTATTTGTATTGCCCTTATCGCGTTTATCTTGTTCTGG
    TTTTTCAAAAAGCCTGAAAAATCTGGACAAAAGGCACAGCAAAAAAAGGGCTACCAAGAG
    ATTCGAGTGGAAGTCATGGGAGGCTATACTCCTGAGTTGATTATCCTCAAGAAATCAGTG
    CCAGCCCGCATTGTCTTTGACCGCAAGGATCCTTCACCATGTCTGGATCAAATTGTTTTT
    CCAGACTTTGGTGTACATGCAGACCTACCTATGGGTGAAGAGTATGTAGTGGAAATCATA
    CCTGAGCAGGCTGGAGAGTATGGTTTCTCTTGTGGCATGAATATGATGCACGGCAAGATG
    ATTGTAGAATAG
    60
    120
    180
    240
    300
    360
    372

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS03045 [old locus tag: MDRSPN_00564 ]
  • symbol: MDRSPN_RS03045
  • description: cupredoxin domain-containing protein
  • length: 123
  • theoretical pI: 5.73952
  • theoretical MW: 13929.4
  • GRAVY: 0.145528

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 14.2)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter periplasmic protein LptC (TIGR04409; HMM-score: 12.3)
    Metabolism Transport and binding proteins Other LPS export ABC transporter periplasmic protein LptC (TIGR04409; HMM-score: 12.3)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    CU_oxidase (CL0026) Cupredoxin_1; Cupredoxin-like domain (PF13473; HMM-score: 79.4)
    and 4 more
    no clan defined Chordopox_A13L; Chordopoxvirus A13L protein (PF05961; HMM-score: 14.6)
    FeoB_associated; FeoB-associated Cys-rich membrane protein (PF12669; HMM-score: 13.9)
    DUF4330; Domain of unknown function (DUF4330) (PF14221; HMM-score: 13.1)
    Saf_2TM; SAVED-fused 2TM effector domain (PF18303; HMM-score: 11.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0007
    • Cytoplasmic Membrane Score: 0.9561
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0431
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.126268
    • TAT(Tat/SPI): 0.002548
    • LIPO(Sec/SPII): 0.010191
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_120164181 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKKGYQEIRVEVMGGYTPELIILKKSVPARIVFDRKDPSPCLDQIVFPDFGVHADLPMGEEYVVEIIPEQAGEYGFSCGMNMMHGKMIVE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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