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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_RS03875 [old locus tag: SP670_0777 ]
  • pan locus tag?: PNEUPAN001650000
  • symbol: SP670_RS03875
  • pan gene symbol?: cupA
  • synonym:
  • product: cupredoxin domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP670_RS03875 [old locus tag: SP670_0777 ]
  • symbol: SP670_RS03875
  • product: cupredoxin domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 733433..733804
  • length: 372
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_014498 (733433..733804) NCBI
  • BioCyc: SP670_RS03875 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0634 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTTAAATAGTATTGTAACCATTATTTGTATTGCCCTTATCGCGTTTATCTTGTTTTGG
    TTTTTCAAAAAGCCTGAAAAATCTGAACAAAAAGCCCAGCAAAAAAACGGATACCAAGAG
    ATTCGAGTGGAAGTCATGGGAGGCTATACTCCTGAGTTGATTGTCCTCAAGAAATCAGTG
    CCAGCACGCATTGTCTTTGACCGCAAGGATCCTTCACCATGTCTGGATCAAATTGTTTTT
    CCAGATTTTGGTGTACATGCGAACCTGCCAATGGGGGAAGAGTATGTAGTGGAAATCACG
    CCTGAACAGGCTGGAGAGTTTGGCTTTGCTTGTGGTATGAACATGATGCACGGCAAGATG
    ATTGTAGAGTAG
    60
    120
    180
    240
    300
    360
    372

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP670_RS03875 [old locus tag: SP670_0777 ]
  • symbol: SP670_RS03875
  • description: cupredoxin domain-containing protein
  • length: 123
  • theoretical pI: 5.17066
  • theoretical MW: 13928.3
  • GRAVY: 0.133333

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Electron transport nitrosocyanin (TIGR03096; HMM-score: 16)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter periplasmic protein LptC (TIGR04409; HMM-score: 13.5)
    Metabolism Transport and binding proteins Other LPS export ABC transporter periplasmic protein LptC (TIGR04409; HMM-score: 13.5)
    and 1 more
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 12.2)
  • TheSEED: see SP670_0777
  • PFAM:
    CU_oxidase (CL0026) Cupredoxin_1; Cupredoxin-like domain (PF13473; HMM-score: 81.8)
    and 5 more
    no clan defined Chordopox_A13L; Chordopoxvirus A13L protein (PF05961; HMM-score: 16.5)
    FeoB_associated; FeoB-associated Cys-rich membrane protein (PF12669; HMM-score: 13.2)
    DUF4330; Domain of unknown function (DUF4330) (PF14221; HMM-score: 13.2)
    Saf_2TM; SAVED-fused 2TM effector domain (PF18303; HMM-score: 12.2)
    ABC-2 (CL0181) ABC_export; Putative ABC exporter (PF16962; HMM-score: 11)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.9355
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0642
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.153155
    • TAT(Tat/SPI): 0.002465
    • LIPO(Sec/SPII): 0.011372
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000935053 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MLNSIVTIICIALIAFILFWFFKKPEKSEQKAQQKNGYQEIRVEVMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPEQAGEFGFACGMNMMHGKMIVE

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]