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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS04710 [old locus tag: MDRSPN_00892 ]
  • pan locus tag?: PNEUPAN002007000
  • symbol: MDRSPN_RS04710
  • pan gene symbol?: —
  • synonym:
  • product: DUF3847 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS04710 [old locus tag: MDRSPN_00892 ]
  • symbol: MDRSPN_RS04710
  • product: DUF3847 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 904251..904568
  • length: 318
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (904251..904568) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGATGGCAAGTAAAAGATTAAGTATTGAAGAACAGATTGAAAAGAAAGAAGAAAGCATT
    AAGCAATTACAAAATCAAAAAAGACAGTTGAAGAAAAAACTTAATGAACAAGAAAGAAAA
    GCAAGAAACAAAAGACTTATAGAAAAAGGTGCAGTGTTTGAAAGTATTTTTGAAGAAAGT
    ATTGATTTAACAAAAGATGAATTTTATAAGTTAATAAAAACGTTAAATGATGAAGAAATA
    AGATTAAACATAATGGAAATTTTAGAAGAAAGAATAGATGATAATGTAGAAAAATCATCT
    AAAGATGAAATAACATAA
    60
    120
    180
    240
    300
    318

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS04710 [old locus tag: MDRSPN_00892 ]
  • symbol: MDRSPN_RS04710
  • description: DUF3847 domain-containing protein
  • length: 105
  • theoretical pI: 5.12613
  • theoretical MW: 12628.4
  • GRAVY: -1.07524

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis type III secretion regulator YopN/LcrE/InvE/MxiC (TIGR02568; HMM-score: 12)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion regulator YopN/LcrE/InvE/MxiC (TIGR02568; HMM-score: 12)
    PRTRC system protein E (TIGR03741; HMM-score: 11)
  • TheSEED:
  • PFAM:
    no clan defined DUF3847; Protein of unknown function (DUF3847) (PF12958; HMM-score: 58.2)
    and 8 more
    DUF2802; Protein of unknown function (DUF2802) (PF10975; HMM-score: 15.4)
    HTH (CL0123) SLIDE; SLIDE (PF09111; HMM-score: 12.3)
    no clan defined Spc24; Spc24 subunit of Ndc80 (PF08286; HMM-score: 10.9)
    Cortex-I_coil; Cortexillin I, coiled coil (PF09304; HMM-score: 9.2)
    RRP14; 60S ribosome biogenesis protein Rrp14 (PF15459; HMM-score: 9.2)
    RapA_C; RNA polymerase recycling family C-terminal (PF12137; HMM-score: 8.9)
    TMEM192; TMEM192 family (PF14802; HMM-score: 7.5)
    LMBR1; LMBR1-like membrane protein (PF04791; HMM-score: 6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9327
    • Cytoplasmic Membrane Score: 0.0202
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.0464
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003221
    • TAT(Tat/SPI): 0.000522
    • LIPO(Sec/SPII): 0.000646
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000968321 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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