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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_RS00280 [old locus tag: MYY_0050 ]
  • pan locus tag?: PNEUPAN000554000
  • symbol: MYY_RS00280
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MYY_RS00280 [old locus tag: MYY_0050 ]
  • symbol: MYY_RS00280
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 44248..44598
  • length: 351
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017769 (44248..44598) NCBI
  • BioCyc: MYY_RS00280 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGAATATAATTGCTATTATCATAATTGTTATTTTTGTTGGAGGTGTCATAGGTGCAGTA
    ATTGATAACCAAAAAAAATCTCCAGAGCAGAGAGAACGTGAACTTGAAACATTTAGAGCA
    AATCAAGAGAAGAAAAAGCAAGAGAAAAAGCAGAATATCATCACTTGCCCTAATTGTAAG
    TCTAAAGATGTGACTTTCTTACAACAAGACAAAAAAGCCTTTTCTGTTGGAAAGGCCGTT
    GGTGGAGCTGTTTTGACTGGTGGAGTTGGTGCTTTAGCTGGATTTGCTGGCAAAAAAGGA
    AATAAACAGTGGCATTGCCAAAATTGCGGAAATTTCTTTGAAACGAAATAA
    60
    120
    180
    240
    300
    351

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MYY_RS00280 [old locus tag: MYY_0050 ]
  • symbol: MYY_RS00280
  • description: hypothetical protein
  • length: 116
  • theoretical pI: 10.331
  • theoretical MW: 12681.7
  • GRAVY: -0.332759

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Anaerobic phenylphosphate carboxylase, delta subunit (TIGR02726; HMM-score: 15.4)
    and 5 more
    Signal transduction Regulatory functions DNA interactions putative regulatory protein, FmdB family (TIGR02605; HMM-score: 12.2)
    Cellular processes Cellular processes Sporulation and germination stage III sporulation protein AE (TIGR02829; HMM-score: 11.2)
    Cys-rich peptide, TIGR04165 family (TIGR04165; HMM-score: 10.7)
    MJ0042 family finger-like domain (TIGR02098; HMM-score: 8.3)
    cxxc_20_cxxc protein (TIGR04104; HMM-score: 6.3)
  • TheSEED: see MYY_0050
  • PFAM:
    no clan defined zf-LITAF-like; LITAF-like zinc ribbon domain (PF10601; HMM-score: 22.7)
    and 26 more
    Zn_Beta_Ribbon (CL0167) Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 16.1)
    Elf1; Transcription elongation factor Elf1 like (PF05129; HMM-score: 15.3)
    Lar_restr_allev; Restriction alleviation protein Lar (PF14354; HMM-score: 15.2)
    Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 15.1)
    TF_Zn_Ribbon; TFIIB zinc-binding (PF08271; HMM-score: 14.1)
    CDA (CL0109) YwqJ-deaminase; YwqJ-like deaminase (PF14431; HMM-score: 14)
    Zn_Beta_Ribbon (CL0167) zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 13.9)
    no clan defined DUF678; Protein of unknown function (DUF678) (PF05077; HMM-score: 13.8)
    DUF3169; Protein of unknown function (DUF3169) (PF11368; HMM-score: 13.5)
    Zn_Beta_Ribbon (CL0167) Prim_Zn_Ribbon; Zinc-binding domain of primase-helicase (PF08273; HMM-score: 13.2)
    TFIIS_C; Transcription factor S-II (TFIIS) (PF01096; HMM-score: 13.1)
    no clan defined DUF1043; Protein of unknown function (DUF1043) (PF06295; HMM-score: 13.1)
    Zn_Beta_Ribbon (CL0167) zf-RING_7; C4-type zinc ribbon domain (PF02591; HMM-score: 13)
    OrfB_Zn_ribbon; Putative transposase DNA-binding domain (PF07282; HMM-score: 12.8)
    no clan defined HypA; Hydrogenase/urease nickel incorporation, metallochaperone, hypA (PF01155; HMM-score: 12.6)
    Zn_Beta_Ribbon (CL0167) zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein (PF10058; HMM-score: 12.3)
    A2L_zn_ribbon; A2L zinc ribbon domain (PF08792; HMM-score: 11.9)
    Zn_Tnp_IS1; InsA N-terminal domain (PF03811; HMM-score: 11.4)
    C2H2-zf (CL0361) zf-H2C2_2; Zinc-finger double domain (PF13465; HMM-score: 10.8)
    zf-FYVE-PHD (CL0390) FYVE; FYVE zinc finger (PF01363; HMM-score: 10.4)
    no clan defined RecR; RecR protein (PF02132; HMM-score: 10.2)
    SpoV; Stage V sporulation protein family (PF08183; HMM-score: 10.2)
    CRA; Circumsporozoite-related antigen (CRA) (PF06589; HMM-score: 9.7)
    C2H2-zf (CL0361) Sgf11; Sgf11 (transcriptional regulation protein) (PF08209; HMM-score: 8.4)
    Zn_Beta_Ribbon (CL0167) zinc_ribbon_4; zinc-ribbon domain (PF13717; HMM-score: 8)
    no clan defined ETRAMP; Malarial early transcribed membrane protein (ETRAMP) (PF09716; HMM-score: 7.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 2
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0016
    • Cytoplasmic Membrane Score: 0.5126
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.4857
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.367557
    • TAT(Tat/SPI): 0.0024
    • LIPO(Sec/SPII): 0.225502
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001020945 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNIIAIIIIVIFVGGVIGAVIDNQKKSPEQRERELETFRANQEKKKQEKKQNIITCPNCKSKDVTFLQQDKKAFSVGKAVGGAVLTGGVGALAGFAGKKGNKQWHCQNCGNFFETK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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