From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_RS11110 [old locus tag: MYY_2108 ]
  • pan locus tag?: PNEUPAN003885000
  • symbol: dusB
  • pan gene symbol?: dusB
  • synonym:
  • product: tRNA dihydrouridine synthase DusB

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MYY_RS11110 [old locus tag: MYY_2108 ]
  • symbol: dusB
  • product: tRNA dihydrouridine synthase DusB
  • replicon: chromosome
  • strand: +
  • coordinates: 2095939..2096919
  • length: 981
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017769 (2095939..2096919) NCBI
  • BioCyc: MYY_RS11110 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_2016 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    GTGACAAATCTTAATACACCTTTTATGATTGGCAATATTGAGATTCCCAATCGTACCGTT
    TTAGCGCCTATGGCTGGCGTGACCAACTCAGCCTTTCGTACCATAGCAAAAGAGCTTGGA
    GCTGGACTCGTTGTAATGGAAATGGTCTCTGACAAGGGAATCCAATACAACAACGAAAAA
    ACCCTGCACATGCTTCATATCGATGAGGGCGAAAACCCTGTCTCTATCCAACTTTTTGGT
    AGCGATGAAGACAGCCTAGCACGCGCAGCAGAATTCATCCAAGAAAACACCAAGACCGAT
    ATCGTCGATATCAACATGGGCTGCCCTGTCAACAAAATCGTGAAGAACGAAGCTGGTGCT
    ATGTGGCTCAAGGGTCCTGACAAGATCTACTCTATCATCAACAAGGTCCAGTCTGTCCTT
    GATATCCCACTTACTGTCAAAATGCGTACCGGCTGGGCGGACCCATCTCTTGCAGTAGAA
    AATGCCCTCGCTGCTGAGGCTGCAGGTGTTTCTGCCCTCGCCATGCATGGCCGTACCCGT
    GAACAAATGTATACTGGCCACGCGGACCTTGAGACCCTTTACAAGGTTGCCCAAGCTCTA
    ACCAAGATTCCATTCATCGCCAACGGTGATATCCGTACTGTCCAAGAAGCCAAGCAACGC
    ATCGAAGAAGTTGGTGCTGACGCAGTCATGATTGGCCGAGCTGCCATGGGAAATCCTTAC
    CTCTTCAACCAAATCAACCATTACTTTGAAACAGGAGAAATCCTACCTGATTTGACATTT
    GAAGACAAGATGAAGATCGCCTACGAACACTTGAAACGATTGATTAACCTCAAAGGAGAA
    AACGTCGCAGTTCGTGAATTCCGCGGCCTCGCTCCTCACTATCTCCGTGGAACATCTGGC
    GCTGCCAAACTCCGTGGAGCCATTTCGCAAGCTAGCACCCTAGCAGAGATTGAAGCTCTC
    TTGCAATTGGAAAAAGTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    981

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MYY_RS11110 [old locus tag: MYY_2108 ]
  • symbol: DusB
  • description: tRNA dihydrouridine synthase DusB
  • length: 326
  • theoretical pI: 5.67475
  • theoretical MW: 35750.9
  • GRAVY: -0.097546

⊟Function[edit | edit source]

  • reaction:
    EC 1.3.1.-?  ExPASy
  • TIGRFAM:
    Unknown function General putative TIM-barrel protein, nifR3 family (TIGR00737; HMM-score: 359.1)
    and 10 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA dihydrouridine synthase A (TIGR00742; EC 1.-.-.-; HMM-score: 103.7)
    dihydroorotate dehydrogenase family protein (TIGR01037; EC 1.3.-.-; HMM-score: 49.3)
    Unknown function General putative TIM-barrel protein (TIGR00736; HMM-score: 33.6)
    Metabolism Amino acid biosynthesis Histidine family imidazoleglycerol phosphate synthase, cyclase subunit (TIGR00735; HMM-score: 23.4)
    glycosyl amidation-associated protein WbuZ (TIGR03572; HMM-score: 23.3)
    Metabolism Energy metabolism Other L-lactate oxidase (TIGR02708; EC 1.1.3.-; HMM-score: 18.8)
    mycofactocin system FadH/OYE family oxidoreductase 2 (TIGR03997; EC 1.-.-.-; HMM-score: 16.9)
    Metabolism Amino acid biosynthesis Histidine family 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (TIGR00007; EC 5.3.1.16; HMM-score: 15.6)
    heme/flavin dehydrogenase, mycofactocin system (TIGR03966; EC 1.-.-.-; HMM-score: 14.9)
    geranylgeranylglyceryl phosphate synthase family protein (TIGR01768; EC 2.5.1.-; HMM-score: 13)
  • TheSEED: see MYY_2108
  • PFAM:
    TIM_barrel (CL0036) Dus; Dihydrouridine synthase (Dus) (PF01207; HMM-score: 301.5)
    and 5 more
    Oxidored_FMN; NADH:flavin oxidoreductase / NADH oxidase family (PF00724; HMM-score: 25.2)
    His_biosynth; Histidine biosynthesis protein (PF00977; HMM-score: 20.6)
    FMN_dh; FMN-dependent dehydrogenase (PF01070; HMM-score: 20.6)
    IMPDH; IMP dehydrogenase / GMP reductase domain (PF00478; HMM-score: 17.2)
    PK_TIM (CL0151) PEP_mutase; Phosphoenolpyruvate phosphomutase (PF13714; HMM-score: 16.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9935
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.006
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009911
    • TAT(Tat/SPI): 0.001565
    • LIPO(Sec/SPII): 0.000942
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000183299 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLVVMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIVDINMGCPVNKIVKNEAGAMWLKGPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVENALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAKQRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLINLKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=MYY_RS11110&oldid=160331"