PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 17-JUN-2018

⊟Summary

• organism: Streptococcus pneumoniae NCTC7466
• locus tag: NCTC7466_01760 [new locus tag: DQM66_RS11925 ]
• pan locus tag^?: PNEUPAN003523000
• symbol: ABC-NBD-truncation_3
• pan gene symbol^?: ABC-NBD-truncation_3
• synonym:
• product: ABC transporter ATP-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: NCTC7466_01760 [new locus tag: DQM66_RS11925 ]
• symbol: ABC-NBD-truncation_3
• product: ABC transporter ATP-binding protein
• replicon: chromosome
• strand: -
• coordinates: 1719061..1719708
• length: 648
• essential: unknown

⊟Accession numbers

• Location: LS483374 (1719061..1719708) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  
  ATGATTTTACTAGCCATTCTCTTTACTTGCTTTTCGGTCTATCTAGAGTTGGAAGTGCCG
  ACCTATATCTCGAAAATTACGGATTTGCTAGGTAGTCAAGGAACTAATTTAGATGAGTTG
  TGGCAGCCGGCAAGCATGATGATGGGAATGCCCTTTCTTGCCTTCTTGTCCGTAGTTGCA
  GTTGGATTTTTTGCATCCCGAGTGGCGGCTTCTTATACTAGTAGGCTGAGAAGTGATATT
  TTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAAGAAATTTTCAATTCCTAGCCTC
  TTGATGCGTACTACCAATGACATTACTCAAGTTCAAATGTTGATTACTATGGACTTGCAA
  GTGGTAACGTGTGGTCCAATTATGGCTATCTGGGCTATTGGGAAGATTTTAGGTCATTCA
  GAATACTGGCTCTGGGCCGTACTTGTGGCAGTGATTGTCAACGTCCTGATGACGACCGTT
  TTGATGACGCTAGCCTTTCCAAAACAGTCCTTGATTCAGGGGCTGACAGATAAACTGAAC
  AGTATCACTCGTGAGAGTTTAACAGGTATTCGTGTCGTTCGTGCCTACAATGCAGAGGAT
  TATCAAAATGAAAAATTTGCAGCAGTAAATGATGAATTGACCCGTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  648
  

⊟Protein

⊟General

• locus tag: NCTC7466_01760 [new locus tag: DQM66_RS11925 ]
• symbol: ABC-NBD-truncation_3
• description: ABC transporter ATP-binding protein
• length: 215
• theoretical pI: 5.22729
• theoretical MW: 24152.3
• GRAVY: 0.467907

⊟Function

• TIGRFAM:
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 48.5)
  Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 48.5)
  Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 43.8)
  ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 39.9)
  and 7 more
  Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 37.4)
  Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 37.4)
  thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 23.7)
  Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 20.6)
  Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 20.6)
  thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 12.9)
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides putative PLP-dependent aminotransferase (TIGR04422; HMM-score: 12.6)
• TheSEED: data available for Hungary19A-6, TIGR4
• PFAM:
  ABC_membrane (CL0241) ABC_membrane; ABC transporter transmembrane region (PF00664; HMM-score: 71.9)
  and 3 more
  no clan defined LRR19-TM; Leucine-rich repeat family 19 TM domain (PF15176; HMM-score: 12.2)
  DUF805; Protein of unknown function (DUF805) (PF05656; HMM-score: 7.5)
  DUF5684; Family of unknown function (DUF5684) (PF18936; HMM-score: 7.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 4
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.018193
  • TAT(Tat/SPI): 0.000214
  • LIPO(Sec/SPII): 0.014185
• predicted transmembrane helices (TMHMM): 4

⊟Accession numbers

• GI:
• RefSeq: SQG02761 NCBI
• UniProt:

⊟Protein sequence

• MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPASMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLMRTTNDITQVQMLITMDLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTVLMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTR

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for TIGR4

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications