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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BM6001
  • locus tag: ODS73_06340 [new locus tag: ODS73_RS06345 ]
  • pan locus tag?: PNEUPAN002446000
  • symbol: ODS73_06340
  • pan gene symbol?: xseB
  • synonym:
  • product: exodeoxyribonuclease VII small subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ODS73_06340 [new locus tag: ODS73_RS06345 ]
  • symbol: ODS73_06340
  • product: exodeoxyribonuclease VII small subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1238877..1239089
  • length: 213
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP107038 (1238877..1239089) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1066 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGTCAAAACAAAAGAAATTTGAGGAAAATCTAGCAGAACTGGAAACCATTGTCCAAAGT
    TTGGAAAATGGTGAAATTGCTCTGGAAGATGCGATTACTGCCTTTCAAAAGGGCATGGTC
    TTGTTAAAAGAGCTCCAAGCTACGCTGGACAAGGCTGAAAAGACCTTGGTCAAGGTCATG
    CAAGAAGACGGAACAGAAAGTGATTTTGAATGA
    60
    120
    180
    213

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ODS73_06340 [new locus tag: ODS73_RS06345 ]
  • symbol: ODS73_06340
  • description: exodeoxyribonuclease VII small subunit
  • length: 70
  • theoretical pI: 4.07767
  • theoretical MW: 7875.9
  • GRAVY: -0.42

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.11.6?  ExPASy
    Exodeoxyribonuclease VII Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates
  • TIGRFAM:
    Genetic information processing DNA metabolism Degradation of DNA exodeoxyribonuclease VII, small subunit (TIGR01280; EC 3.1.11.6; HMM-score: 72)
    and 2 more
    Genetic information processing Protein fate Protein folding and stabilization prefoldin, alpha subunit (TIGR00293; HMM-score: 13.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase (TIGR02029; EC 1.14.13.81; HMM-score: 11.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Exonuc_VII_S; Exonuclease VII small subunit (PF02609; HMM-score: 65.6)
    and 7 more
    DUF6687; Family of unknown function (DUF6687) (PF20392; HMM-score: 15.8)
    Trimer_CC; Trimerisation motif (PF08954; HMM-score: 14.9)
    KxDL; Uncharacterized conserved protein (PF10241; HMM-score: 14.2)
    FliS; Flagellar protein FliS (PF02561; HMM-score: 13.1)
    DUF745; Protein of unknown function (DUF745) (PF05335; HMM-score: 12.7)
    HTH (CL0123) RuvB_C; RuvB C-terminal winged helix domain (PF05491; HMM-score: 12.7)
    Hybrid (CL0105) OEP; Outer membrane efflux protein (PF02321; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00138
    • TAT(Tat/SPI): 0.000214
    • LIPO(Sec/SPII): 0.000173
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WIA44828 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLLKELQATLDKAEKTLVKVMQEDGTESDFE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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