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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-SEP-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BM6001
  • locus tag: ODS73_10710 [new locus tag: ODS73_RS10720 ]
  • pan locus tag?: PNEUPAN000496000
  • symbol: ODS73_10710
  • pan gene symbol?: —
  • synonym:
  • product: phage holin family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ODS73_10710 [new locus tag: ODS73_RS10720 ]
  • symbol: ODS73_10710
  • product: phage holin family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2043755..2044087
  • length: 333
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP107038 (2043755..2044087) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGCAACAAATTACTGAAATCATTACTAATGGAGCAATCAGCATCCTAGTCGTTTTGGCA
    GGGGTTGTAGTTAGGGCAGTCAAGGACTACCTGGTTCAAAAAGGTGGAGAAAAGACCATC
    AAGATTGTTGAAATCTTGGCCAAAAATGCAGTAAATGCCGTGGAGCAGGTAGCTGCTGAA
    ACTGGCTACAAGGGAGATGAAAAACTGGAGCAGGCTCGTGCTAAAGTCCGTGCTGAGCTT
    ACAAAATACAATATTAGCATGACTGACAAAAACTTAGACACCTTCGTAGAGTCAGCAGTG
    AAGCAGATGAATGACGCATGGAAAGGACGATAG
    60
    120
    180
    240
    300
    333

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ODS73_10710 [new locus tag: ODS73_RS10720 ]
  • symbol: ODS73_10710
  • description: phage holin family protein
  • length: 110
  • theoretical pI: 9.47367
  • theoretical MW: 12078.9
  • GRAVY: -0.117273

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage holin, LL-H family (TIGR01673; HMM-score: 56.9)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    no clan defined Phage_holin_6_1; Bacteriophage holin of superfamily 6 (Holin_LLH) (PF09682; HMM-score: 94.1)
    and 5 more
    Oxa1 (CL0376) EMC3_TMCO1; Integral membrane protein EMC3/TMCO1-like (PF01956; HMM-score: 14)
    no clan defined MRP-S26; Mitochondrial ribosome subunit S26 (PF14943; HMM-score: 13.5)
    Mis12; Mis12 protein (PF05859; HMM-score: 12.7)
    ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4 (PF12896; HMM-score: 12.1)
    DUF2232; Predicted membrane protein (DUF2232) (PF09991; HMM-score: 10.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.261687
    • TAT(Tat/SPI): 0.002418
    • LIPO(Sec/SPII): 0.008783
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WIA45589 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVEILAKNAVNAVEQVAAETGYKGDEKLEQARAKVRAELTKYNISMTDKNLDTFVESAVKQMNDAWKGR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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