PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 08-SEP-2024

⊟Summary

• organism: Streptococcus pneumoniae BM6001
• locus tag: ODS73_RS01215 [old locus tag: ODS73_01215 ]
• pan locus tag^?: PNEUPAN000873000
• symbol: ODS73_RS01215
• pan gene symbol^?: —
• synonym:
• product: ABC transporter permease

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: ODS73_RS01215 [old locus tag: ODS73_01215 ]
• symbol: ODS73_RS01215
• product: ABC transporter permease
• replicon: chromosome
• strand: +
• coordinates: 211849..212382
• length: 534
• essential: unknown

⊟Accession numbers

• Location: NZ_CP107038 (211849..212382) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_0159 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  
  ATGAAAAAGAAACCAATTTATCTATGGGTCTTGCTAATCTTGTCTGCCCTTATTTCAGTT
  CCGTCTCTGTTTGGAATTGTGAGTCCCTTGCCTAGTAAGGAAGCCCTTCGTGCTGCTCAG
  AAACAAGTTGCAGGGGTCAATGCTCAGCAATTAGAAGACCAGCTTAATTATACCTATAGA
  GTAGCAGAAGCATCTCATTCTATTTTTAATGTTGCTTTGATTGTGCTATCTACTATTTTA
  GTGGTCGTAGCGATTGTCTTCCTTGTTCGTAAAAATTTGCAATATGCAAACTATACTTAC
  GTTGGCTATGTTTTGTTAGCTATTATTGGTTCGATTTATGGCTATGTTGGTTTACAAGAC
  GCTGTGCAGTTGGTTCAAGATGAGAGCATGCGTTTGACAGTGAGTATTGGTTCAAAAGCT
  GTTAGCATTTTCTATATCGTCATCAATGTTCTCTTCCTAGCCCTTGTCTTCTATAAGATG
  TGGCGACAACAGAAAGCCTTGGCAGAAGAAGAGGAAACAGAAGAGCTTGCCTAA
  60
  120
  180
  240
  300
  360
  420
  480
  534
  

⊟Protein

⊟General

• locus tag: ODS73_RS01215 [old locus tag: ODS73_01215 ]
• symbol: ODS73_RS01215
• description: ABC transporter permease
• length: 177
• theoretical pI: 8.67357
• theoretical MW: 19775.2
• GRAVY: 0.615819

⊟Function

• TIGRFAM:
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  no clan defined DUF3169; Protein of unknown function (DUF3169) (PF11368; HMM-score: 21.5)
  OSTbeta; Organic solute transporter subunit beta protein (PF15048; HMM-score: 19.9)
  and 17 more
  DUF2157; Predicted membrane protein (DUF2157) (PF09925; HMM-score: 16.6)
  DHHC; DHHC palmitoyltransferase (PF01529; HMM-score: 14.9)
  DUF4052; Protein of unknown function (DUF4052) (PF13261; HMM-score: 14.2)
  2heme_cytochrom (CL0328) DUF2231; Predicted membrane protein (DUF2231) (PF09990; HMM-score: 13.4)
  no clan defined PspB; Phage shock protein B (PF06667; HMM-score: 13)
  TRP; Transient receptor potential (TRP) ion channel (PF06011; HMM-score: 12.6)
  DUF846; Eukaryotic protein of unknown function (DUF846) (PF05832; HMM-score: 12.4)
  GPCR_A (CL0192) Ceramidase; Ceramidase (PF05875; HMM-score: 12.2)
  no clan defined Trp_oprn_chp; Tryptophan-associated transmembrane protein (Trp_oprn_chp) (PF09534; HMM-score: 12)
  MAP17; Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 (PF15807; HMM-score: 10.8)
  DUF3671; Protein of unknown function (PF12420; HMM-score: 9.5)
  Renin_r; Renin receptor-like protein (PF07850; HMM-score: 9.3)
  DUF202; Domain of unknown function (DUF202) (PF02656; HMM-score: 7.9)
  SLATT (CL0676) DUF4231; Protein of unknown function (DUF4231) (PF14015; HMM-score: 7.7)
  no clan defined DUF4282; Domain of unknown function (DUF4282) (PF14110; HMM-score: 7.4)
  Tetraspannin (CL0347) Tetraspanin; Tetraspanin family (PF00335; HMM-score: 6.8)
  no clan defined DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 6.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 4
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0.0004
  • Cytoplasmic Membrane Score: 0.9016
  • Cell wall & surface Score: 0.0006
  • Extracellular Score: 0.0975
• SignalP: Signal peptide SP(Sec/SPI) length 38 aa
  • SP(Sec/SPI): 0.888298
  • TAT(Tat/SPI): 0.030468
  • LIPO(Sec/SPII): 0.02538
  • Cleavage Site: CS pos: 38-39. LRA-AQ. Pr: 0.2088
• predicted transmembrane helices (TMHMM): 4

⊟Accession numbers

• GI:
• RefSeq: WP_000729029 NCBI
• UniProt:

⊟Protein sequence

• MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVAGVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVGYVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKMWRQQKALAEEEETEELA

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_0159 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications