PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN000101000
• symbol^?: cps4I
• synonym: wecB
• description^?: non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase

  descriptions from strain specific annotations:

  • non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase
  • UDP-N-acetylglucosamine-2-epimerase
  • capsular polysaccharide biosynthesis protein Cps4I
  • UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
  • UDP-N-acetylglucosamine 2-epimerase mnaA
• strand^?: +
• coordinates^?: 83080..84168
• occurrence^?: in 40% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS01745 (cps4I)
(2)
D39:
—
(2)
D39V:
—
(19A)
Hungary19A-6:
SPH_RS02260 (wecB)
(19F)
EF3030:
EF3030_RS01725 (wecB)
(6B)^?
670-6B:
—
(6A)
6A-10:
—
(5)
70585:
—
(19F)
A026:
T308_RS01780 (wecB)
(3)
A66:
—
(11A)
AP200:
—
(12F)
ASP0581:
EL334_RS01930 (wecB)
(19F)
ATCC 49619:
EL263_RS01950 (wecB)
(23F)
ATCC 700669:
—
(19F)
BM6001:
ODS73_RS02225 (wecB)
(1)
BVJ1JL:
—
(14)
CGSP14:
—
(19F)
G54:
SPG_RS01645 (wecB)
(1)
gamPNI0373:
—
(3)
HU-OH:
—
(19A)
Hu15:
SPNHU15_RS02025 (wecB)
(19A)
Hu17:
SPNHU17_RS01955 (wecB)
(1)
INV104:
—
(14)
INV200:
—
(14)
JJA:
—
(19F)
MDRSPN001:
MDRSPN_RS01735 (wecB)
(1)
NCTC7465:
—
(2)
NCTC7466:
—
(4)
NU83127:
EL277_RS01840 (cps4I)
(3)
OXC141:
—
(1)
P1031:
—
(2)
R6:
—
(19A)
SP49:
BMJ42_RS02445 (wecB)
(1)
SPN032672:
—
(3)
SPN034156:
—
(3)
SPN034183:
—
(3)
SPN994038:
—
(3)
SPN994039:
—
(3)
SPNA45:
—
(19F)
ST556:
MYY_RS02250 (wecB)
(19F)
Taiwan19F-14:
SPT_RS02040 (wecB)
(19A)
TCH8431/19A:
HMPREF0837_RS03205 (wecB)
(4)
Xen35:
CXP32_RS01795 (cps4I)

⊟Genome Viewer

TIGR4
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MKKVVVVFGTRPEAIKMCPLVKELRTRKNIETLVCVTGQHRQMLDQVLDTFGIIPDFDLS
  Hungary19A-6    MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMVSPVLDLFGVVPDYDLE
  EF3030          MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMVSPVLDLFGVQPDYDLE
                  ***:::************.**:**:.:::::*:*******::*:. *** **: **:**.
  
  TIGR4           IMKDKQTLFDVTIGILEGMKAILESEKPDLVLVHGDTSTTFASSLAAFYLQIPIGHVEAG
  Hungary19A-6    IMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAG
  EF3030          IMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYAAALAAFYLGIKVGHVEAG
                  *** :*.**.:* .*** :*.:**.*:**:*******:**:*::****** * :******
  
  TIGR4           LRTYDIYSPYPEEFNRQAVGVLAQYHFTPTQLSKDNLLREGKTPESIFVTGNTAIDALQT
  Hungary19A-6    LRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKEGR--ENVYVTGNTVIDALTT
  EF3030          LRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKEGR--NNIYVTGNTVIDALTT
                  ****:: **:*******:..::* ***:**:*:*:**::**:  :.::*****.**** *
  
  TIGR4           TIQEDYTHPELEWIGESRFILITAHRRENLGEPMRHMFRAIRRIIEEYSDVKAIYPIHMN
  Hungary19A-6    TVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYEDVKVIYPIHKN
  EF3030          TVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRAVKRVLNEYDDVKVIYPIHKN
                  *:*:****..*:    .*:**:******************::*:::**.***.***** *
  
  TIGR4           PRVRQIAEEELSGCERIKMIEPLEVLDFHNFLSRSYLILTDSGGIQEEAPSLGKPVLVMR
  Hungary19A-6    PLVRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMILTDSGGVQEEAPSLGKPVLVMR
  EF3030          PLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMILTDSGGVQEEAPSLGKPVLVMR
                  * **: * * :.. ***::****:*******:.:**:*******:***************
  
  TIGR4           DTTERPEGIEAGTLKLVGADENNIYRHFKELLENDSVYQAMSQASNPYGDGTACKKIADI
  Hungary19A-6    DTTERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSGEYKKMSQASNPYGNGDASQQIVQI
  EF3030          DTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPEEYKKMSQASNPYGNGDASKQIVRI
                  ********: ********:**:.**::** **::   *: *********:* *.::*. *
  
  TIGR4           LEGEV
  Hungary19A-6    LRG-I
  EF3030          LRG-I
                  *.* :