PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN001603000
• symbol^?: murD
• synonym:
• description^?: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase

  descriptions from strain specific annotations:

  • UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
  • UDP-N-acetylmuramoylalanine--D-glutamate ligase
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
  • MurD D-glutamic acid adding enzyme
• strand^?: +
• coordinates^?: 2040046..2041398
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS03370 (murD)
(2)
D39:
SPD_RS03230 (murD)
(2)
D39V:
SPV_RS03225 (murD)
(19A)
Hungary19A-6:
SPH_RS03795 (murD)
(19F)
EF3030:
EF3030_RS03235 (murD)
(6B)^?
670-6B:
SP670_RS03720 (murD)
(6A)
6A-10:
HKM25_RS03285 (murD)
(5)
70585:
SP70585_RS03660 (murD)
(19F)
A026:
T308_RS03275 (murD)
(3)
A66:
A66_RS03125 (murD)
(11A)
AP200:
SPAP_RS03345 (murD)
(12F)
ASP0581:
EL334_RS03440 (murD)
(19F)
ATCC 49619:
EL263_RS03390 (murD)
(23F)
ATCC 700669:
SPN23F_RS03175 (murD)
(19F)
BM6001:
ODS73_RS03665 (murD)
(1)
BVJ1JL:
JN057_RS03390 (murD)
(14)
CGSP14:
SPCG_RS03370 (murD)
(19F)
G54:
SPG_RS03180 (murD)
(1)
gamPNI0373:
HMPREF1038_RS03505 (murD)
(3)
HU-OH:
EL271_RS03185 (murD)
(19A)
Hu15:
SPNHU15_RS03455 (murD)
(19A)
Hu17:
SPNHU17_RS03395 (murD)
(1)
INV104:
INV104_RS03370 (murD)
(14)
INV200:
SPNINV200_RS03245 (murD)
(14)
JJA:
SPJ_RS03190 (murD)
(19F)
MDRSPN001:
MDRSPN_RS07200 (murD)
(1)
NCTC7465:
AT689_RS10300 (murD)
(2)
NCTC7466:
DQM66_RS03230 (murD)
(4)
NU83127:
EL277_RS03470 (murD)
(3)
OXC141:
SPNOXC_RS03370 (murD)
(1)
P1031:
SPP_RS03450 (murD)
(2)
R6:
SPR_RS03055 (murD)
(19A)
SP49:
BMJ42_RS03960 (murD)
(1)
SPN032672:
SPN032672_RS09630 (murD)
(3)
SPN034156:
SPN034156_RS09295 (murD)
(3)
SPN034183:
SPN034183_RS03385 (murD)
(3)
SPN994038:
SPN994038_RS03305 (murD)
(3)
SPN994039:
SPN994039_RS03305 (murD)
(3)
SPNA45:
SPNA45_RS05755 (murD)
(19F)
ST556:
MYY_RS03755 (murD)
(19F)
Taiwan19F-14:
SPT_RS03535 (murD)
(19A)
TCH8431/19A:
HMPREF0837_RS04705 (murD)
(4)
Xen35:
CXP32_RS03445 (murD)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVI
  D39             MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVI
  D39V            MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVI
  Hungary19A-6    MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVI
  EF3030          MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVI
                  ************************************************************
  
  TIGR4           TGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGS
  D39             TGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKRIPVLTEVELAYLISEAPIIGITGS
  D39V            TGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKRIPVLTEVELAYLISEAPIIGITGS
  Hungary19A-6    TGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGS
  EF3030          TGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGS
                  *********************************** ************************
  
  TIGR4           NGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFH
  D39             NGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFH
  D39V            NGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFH
  Hungary19A-6    NGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFH
  EF3030          NGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFH
                  ************************************************************
  
  TIGR4           PEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATV
  D39             PEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATV
  D39V            PEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATV
  Hungary19A-6    PEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATV
  EF3030          PEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAADFLVLNFNQDLVKDLASKTEATV
                  ****************** *.***************************.***:*******
  
  TIGR4           VPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTI
  D39             VPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTI
  D39V            VPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTI
  Hungary19A-6    IPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTI
  EF3030          VPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRGVDNQTI
                  :****************************************************.******
  
  TIGR4           KETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGN
  D39             KETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGN
  D39V            KETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGN
  Hungary19A-6    KETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGN
  EF3030          KETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGN
                  ************************************************************
  
  TIGR4           EFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVL
  D39             EFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVL
  D39V            EFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVL
  Hungary19A-6    EFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELAIQGDVVL
  EF3030          EFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVL
                  ***************************************************** ******
  
  TIGR4           LSPANASWDMYANFEVRGDLFIDTVAELKE
  D39             LSPANASWDMYANFEVRGDLFIDTVAELKE
  D39V            LSPANASWDMYANFEVRGDLFIDTVAELKE
  Hungary19A-6    LSPANASWDMYANFEVRGDLFIDTVAELKE
  EF3030          LSPANASWDMYANFEVRGDLFIDTVAELKE
                  ******************************