PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002018000
• symbol^?: phtE
• synonym:
• description^?: pneumococcal histidine triad protein PhtE

  descriptions from strain specific annotations:

  • pneumococcal histidine triad protein PhtE
  • pneumococcal histidine triad protein E
  • pneumococcal histidine triad protein E (Bvh-3)
  • HIT family hydrolase
  • Pneumococcal histidine triad protein E precursor
  • conserved hypothetical protein
  • histidine triad protein
  • histidine triad protein E
  • pneumococcal histidine triad protein B
  • pneumococcal histidine triad protein D
  • pneumococcal-type histidine triad protein
  • Streptococcal histidine triad protein
  • pseudogene
• strand^?: +
• coordinates^?: 2497887..2501035
• occurrence^?: in 100% of 43 strains

⊟Orthologs

TIGR4:
SP_RS04980 (phtE)
D39:
SPD_RS04785 (phtE)
D39V:
SPV_RS05555 (phtE)
Hungary19A-6:
SPH_RS05355 (phtE)
EF3030:
EF3030_RS04840 (phtE)
670-6B:
SP670_RS06510 (phtE)
6A-10:
HKM25_RS04760 (phtE)
70585:
SP70585_RS05200 (phtE)
A026:
T308_RS04925 (phtE)
A66:
A66_RS04540 (phtE)
AP200:
SPAP_RS05945 (phtE)
ASP0581:
EL334_RS05015 (phtE)
ATCC 49619:
EL263_RS04975 (phtE)
ATCC 700669:
SPN23F_RS04730 (phtE)
BM6001:
ODS73_RS05160 (phtE)
BVJ1JL:
JN057_RS04815 (phtE)
CGSP14:
SPCG_RS05085 (phtE)
G54:
SPG_RS04675 (phtE)
gamPNI0373:
HMPREF1038_RS05825 (phtE)
HU-OH:
EL271_RS04705 (phtE)
Hu15:
SPNHU15_RS04900 (phtE)
Hu17:
SPNHU17_RS04825 (phtE)
INV104:
INV104_RS05050 (phtE)
INV200:
SPNINV200_RS04935 (phtE)
JJA:
SPJ_RS04725 (phtE)
MDRSPN001:
MDRSPN_RS04510 (phtE)
NCTC7465:
AT689_RS08800 (phtE)
NCTC7466:
DQM66_RS05565 (phtE)
NU83127:
EL277_RS05055 (phtE)
OXC141:
SPNOXC_RS04895 (phtE)
P1031:
SPP_RS04995 (phtE)
R6:
SPR_RS04540 (phtE)
SP49:
BMJ42_RS05565 (phtE)
SPN032672:
SPN032672_RS11320 (phtE)
SPN034156:
SPN034156_RS10790 (phtE)
SPN034183:
SPN034183_RS04915 (phtE)
SPN994038:
SPN994038_RS04820 (phtE)
SPN994039:
SPN994039_RS04825 (phtE)
SPNA45:
SPNA45_RS07335
ST556:
MYY_RS05395 (phtE)
Taiwan19F-14:
SPT_RS05185 (phtE)
TCH8431/19A:
HMPREF0837_RS07090 (phtE)
Xen35:
CXP32_RS05015 (phtE)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVS
  D39             MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVS
  D39V            MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVS
  Hungary19A-6    MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVS
                  ************************************************************
  
  TIGR4           QKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVN
  D39             QKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVN
  D39V            QKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVN
  Hungary19A-6    QKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVN
                  ************************************************************
  
  TIGR4           EVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEHVKDNEKVNSNVAVARSQGRY
  D39             EVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEHVKDNEKVNSNVAVARSQGRY
  D39V            EVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEHVKDNEKVNSNVAVARSQGRY
  Hungary19A-6    EVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEHVKDNEKVNSNVAVARSQGRY
                  ************************************************************
  
  TIGR4           TTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPSQLS
  D39             TTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPSQLS
  D39V            TTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPSQLS
  Hungary19A-6    TTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPSQLS
                  ************************************************************
  
  TIGR4           YSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISR
  D39             YSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISR
  D39V            YSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISR
  Hungary19A-6    YSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISR
                  ************************************************************
  
  TIGR4           TPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPISGTGSTVSTNAKPNEVVSSLGSLSSN
  D39             TPNGVAIPHGDHYHFIPYSKLSALEEKIARRVPISGTGSTVSTNAKPNEVVSSLGSLSSN
  D39V            TPNGVAIPHGDHYHFIPYSKLSALEEKIARRVPISGTGSTVSTNAKPNEVVSSLGSLSSN
  Hungary19A-6    TPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPISGTGSTVSTNAKPNEVVSSLGSLSSN
                  ****************************** *****************************
  
  TIGR4           PSSLTTSKELSSASDGYIFNPKDIVEETATAYIVRHGDHFHYIPKSNQIGQPTLPNNSLA
  D39             PSSLTTSKELSSASDGYIFNPKDIVEETATAYIVRHGDHFHYIPKSNQIGQPTLPNNSLA
  D39V            PSSLTTSKELSSASDGYIFNPKDIVEETATAYIVRHGDHFHYIPKSNQIGQPTLPNNSLA
  Hungary19A-6    PSSLTTSKELSSASDGYIFNPKDIVEETATAYIVRHGDHFHYIPKSNQIGQPTLPNNSLA
                  ************************************************************
  
  TIGR4           TPSPSLPINPGTSHEKHEEDGYGFDANRIIAEDESGFVMSHGDHNHYFFKKDLTEEQIKA
  D39             TPSPSLPINPGISHEKHEEDGYGFDANRIIAEDESGFIMSHGNHNHYFFKKDLTEEQIKA
  D39V            TPSPSLPINPGISHEKHEEDGYGFDANRIIAEDESGFIMSHGNHNHYFFKKDLTEEQIKA
  Hungary19A-6    TPSPSLPINPGTSHEKHEEDGYGFDANRIIAEDESGFVMSHGDHNHYFFKKDLTEEQIKA
                  *********** *************************:****:*****************
  
  TIGR4           AQKHLEEVKTSHNGLDSLSSHEQDYPSNAKEMKDLDKKIEEKIAGIMKQYGVKRESIVVN
  D39             AQKHLEEVKTSHNGLDSLSSHEQDYPGNAKEMKDLDKKIEEKIAGIMKQYGVKRESIVVN
  D39V            AQKHLEEVKTSHNGLDSLSSHEQDYPGNAKEMKDLDKKIEEKIAGIMKQYGVKRESIVVN
  Hungary19A-6    AQKHLEEVKTSHNGLDSLSSHEQDYPGNAKEMKDLDKKIEEKIAGIMKQYGVKRESIVVN
                  **************************.*********************************
  
  TIGR4           KEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNV
  D39             KEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNV
  D39V            KEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNV
  Hungary19A-6    KEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNV
                  ************************************************************
  
  TIGR4           VNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFG
  D39             VNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFG
  D39V            VNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFG
  Hungary19A-6    VNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFG
                  ************************************************************
  
  TIGR4           EGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHA
  D39             EGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHA
  D39V            EGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHA
  Hungary19A-6    EGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHA
                  ************************************************************
  
  TIGR4           GDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNK
  D39             GDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNK
  D39V            GDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNK
  Hungary19A-6    GDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNK
                  ************************************************************
  
  TIGR4           IPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSILPQFKRNKAQENLKLDEKVEEPKTS
  D39             IPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTS
  D39V            IPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTS
  Hungary19A-6    IPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTS
                  *********************************************** ************
  
  TIGR4           EKVEKEKLSETGNSTSNSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLP
  D39             EKVEKEKLSETGNSTSNSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLP
  D39V            EKVEKEKLSETGNSTSNSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLP
  Hungary19A-6    EKVEKEKLSETGNSTSNSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLP
                  ************************************************************
  
  TIGR4           SGEVIKKNMADFTGEAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKP
  D39             SGEVIKKNMADFTGEAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKP
  D39V            SGEVIKKNMADFTGEAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKP
  Hungary19A-6    SGEVIKKNMADFTGEAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKP
                  ************************************************************
  
  TIGR4           ENSTDNGMLNPEGNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTI
  D39             ENSTDNGMLNPEGNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTI
  D39V            ENSTDNGMLNPEGNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTI
  Hungary19A-6    ENSTDNGMLNPEGNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTI
                  ************************************************************
  
  TIGR4           ELRLPSGEVIKKNLSDLIA
  D39             ELRLPSGEVIKKNLSDLIA
  D39V            ELRLPSGEVIKKNLSDLIA
  Hungary19A-6    ELRLPSGEVIKKNLSDFIA
                  ****************:**