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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 19-SEP-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_RS07090 [old locus tag: HMPREF0837_11480 ]
  • pan locus tag?: PNEUPAN002079000
  • symbol: phtE
  • pan gene symbol?: phtE
  • synonym:
  • product: pneumococcal histidine triad protein PhtE

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_RS07090 [old locus tag: HMPREF0837_11480 ]
  • symbol: phtE
  • product: pneumococcal histidine triad protein PhtE
  • replicon: chromosome
  • strand: -
  • coordinates: 1365473..1368592
  • length: 3120
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014251 (1365473..1368592) NCBI
  • BioCyc: HMPREF0837_RS07090 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0890 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    ATGAAATTTAGTAAAAAATATATAGCAGCTGGATCAGCTGTTATCGTATCCTTGAGTCTA
    TGTGCCTATGCACTAAACCAGCATCGTTCGCAGGAAAATAAGGACAATAATCGTGTCTCT
    TATGTGGATGGCAGCCAGTCAAGTCAGAAAAGTGAAAACTTGACACCAGACCAGGTTAGC
    CAGAAAGAAGGAATTCAGGCTGAGCAAATTGTAATCAAAATTACAGATCAGGGCTATGTA
    ACGTCACACGGTGACCACTATCATTACTATAATGGGAAAGTTCCTTATGATGCCCTCTTT
    AGTGAAGAACTCTTGATGAAGGATCCAAACTATCAACTTAAAGACGCTGATATTGTCAAT
    GAAGTCAAGGGTGGTTATATCATCAAGGTCGATGGAAAATATTATGTCTACCTGAAAGAT
    GCAGCTCATGCTGATAATGTTCGAACTAAAGATGAAATCAATCGTCAAAAACAAGAACAT
    GTCAAAGATAATGAGAAGGTTAACTCTAATGTTGCTGTAGCAAGGTCTCAGGGACGATAT
    ACGACAAATGATGGTTATGTCTTTAATCCAGCTGATATTATCGAAGATACGGGTAATGCT
    TATATCGTTCCTCATGGAGGTCACTATCACTACATTCCCAAAAGCGATTTATCTGCTAGT
    GAATTAGCAGCAGCTAAAGCACATCTGGCTGGAAAAAATATGCAACCGAGTCAGTTAAGC
    TATTCTTCAACAGCTAGTGACAATAACACGCAATCTGTAGCAAAAGGATCAACTAGCAAG
    CCAGCAAATAAATCTGAAAATCTCCAGAGTCTTTTGAAGGAACTCTATGATTCACCTAGC
    GCCCAACGTTACAGTGAATCAGATGGCCTGGTCTTTGACCCTGCTAAGATTATCAGTCGT
    ACACCAAATGGAGTTGCGATTCCGCATGGCGACCATTACCACTTTATTCCTTACAGCAAG
    CTTTCTGCCTTAGAAGAAAAGATTGCCAGAATGGTGCCTATCAGTGGAACTGGTTCTACA
    GTTTCTACAAATGCAAAACCTAATGAAGTAGTGTCTAGTCTAGGCAGTCTTTCAAGCAAT
    CCTTCTTCTTTAACGACAAGTAAGGAGCTCTCTTCAGCATCTGATGGTTATATTTTTAAT
    CCAAAAGATATCGTTGAAGAAACGGCTACAGCTTATATTGTAAGACATGGTGATCATTTC
    CATTACATTCCAAAATCAAATCAAATTGGGCAACCGACTCTTCCAAACAATAGTCTAGCA
    ACACCTTCTCCATCTCTTCCAATCAATCCAGGAACTTCACATGAGAAACATGAAGAAGAT
    GGATACGGATTTGATGCTAATCGTATTATCGCTGAAGATGAATCAGGTTTTGTCATGAGT
    CACGGAGACCACAATCATTATTTCTTCAAGAAGGACTTGACAGAAGAGCAAATTAAGGCT
    GCGCAAAAACATTTAGAGGAAGTTAAAACTAGTCATAATGGATTAGATTCTTTGTCATCT
    CATGAACAGGATTATCCAAGTAATGCCAAAGAAATGAAAGATTTAGATAAAAAAATCGAA
    GAAAAAATTGCTGGCATTATGAAACAATATGGTGTCAAACGTGAAAGTATTGTCGTGAAT
    AAAGAAAAAAATGCGATTATTTATCCGCATGGAGATCACCATCATGCAGATCCGATTGAT
    GAACATAAACCGGTTGGAATTGGTCATTCTCACAGTAACTATGAACTGTTTAAACCCGAA
    GAAGGAGTTGCTAAAAAAGAAGGGAATAAAGTTTATACTGGAGAAGAATTAACGAATGTT
    GTTAATTTGTTAAAAAATAGTACGTTTAATAATCAAAACTTTACTCTAGCCAATGGTCAA
    AAACGCGTTTCTTTTAGTTTTCCGCCTGAATTGGAGAAAAAATTAGGTATCAATATGCTA
    GTAAAATTAATAACACCAGATGGAAAAGTATTGGAGAAAGTATCTGGTAAAGTATTTGGA
    GAAGGAGTAGGGAATATTGCAAACTTTGAATTAGATCAACCTTATTTACCAGGACAAACA
    TTTAAGTATACTATCGCTTCAAAAGATTATCCAGAAGTAAGTTATGATGGTACATTTACA
    GTTCCAACCTCTTTAGCTTACAAAATGGCCAGTCAAACGATTTTCTATCCTTTCCATGCA
    GGGGATACTTATTTAAGAGTGAACCCTCAATTTGCAGTGCCTAAAGGAACTGATGCTTTA
    GTCAGAGTGTTTGATGAATTTCATGGAAATGCTTATTTAGAAAATAACTATAAAGTTGGT
    GAAATCAAATTACCGATTCCGAAATTAAACCAAGGAACAACCAGAACGGCCGGAAATAAA
    ATTCCTGTAACCTTCATGGCAAATGCTTATTTGGACAATCAATCGACTTATATTGTGGAA
    GTACCTATCTTGGAAAAAGAAAATCAAACTGATAAACCAAGTATTCTACCACAATTTAAA
    AGGAATAAAGCACAAGAAAACTCAAAACTTGATGAAAAGGTAGAAGAACCAAAGACTAGT
    GAGAAGGTAGAAAAAGAAAAACTTTCTGAAACTGGGAATAGTACTAGTAATTCAACGTTA
    GAAGAAGTTCCTACAGTGGATCCTGTACAAGAAAAAGTAGCAAAATTTGCTGAAAGTTAT
    GGGATGAAGCTAGAAAATGTCTTGTTTAATATGGACGGAACAATTGAATTATATTTACCA
    TCGGGAGAAGTCATTAAAAAGAATATGGCAGATTTTACAGGAGAAGCACCTCAAGGAAAT
    GGTGAAAATAAACCATCTGAAAATGGAAAAGTATCTACTGGAACAGTTGAGAACCAACCA
    ACAGAAAATAAACCAGCAGATTCTTTACCAGAGGCACCAAACGAAAAACCTGTAAAACCA
    GAAAACTCAACGGATAATGGAATGTTGAATCCAGAAGGGAATGTGGGGAGTGACCCTATG
    TTAGATCCAGCATTAGAGGAAGCTCCAGCAGTAGATCCTGTACAAGAAAAATTAGAAAAA
    TTTACAGCTAGTTACGGATTAGGCTTAGATAGTGTTATATTCAATATGGATGGAACGATT
    GAATTAAGATTGCCAAGTGGAGAAGTGATAAAAAAGAATTTATCTGATCTCATAGCGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
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    1860
    1920
    1980
    2040
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    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_RS07090 [old locus tag: HMPREF0837_11480 ]
  • symbol: PhtE
  • description: pneumococcal histidine triad protein PhtE
  • length: 1039
  • theoretical pI: 5.54279
  • theoretical MW: 114605
  • GRAVY: -0.676805

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis streptococcal histidine triad protein (TIGR01363; HMM-score: 561.6)
  • TheSEED: see HMPREF0837_11480
  • PFAM:
    no clan defined Strep_his_triad; Streptococcal histidine triad protein (PF04270; HMM-score: 269.7)
    and 3 more
    PH (CL0266) YcxB; YcxB-like protein (PF14317; HMM-score: 20.3)
    no clan defined PHtD_u1; Unstructured region on Pneumococcal histidine triad protein (PF16645; HMM-score: 16.1)
    CDA (CL0109) DddA-like; Double-stranded DNA deaminase toxin A (PF14428; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • SignalP: Signal peptide LIPO(Sec/SPII) length 20 aa
    • SP(Sec/SPI): 0.451368
    • TAT(Tat/SPI): 0.001325
    • LIPO(Sec/SPII): 0.533822
    • Cleavage Site: CS pos: 20-21. LSL-CA. Pr: 0.4587
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEHVKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPISGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAYIVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRIIAEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSNAKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTSNSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTGEAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPEGNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKNLSDLIA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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