PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002386000
• symbol^?: acoL
• synonym: lpdA
• description^?: dihydrolipoyl dehydrogenase

  descriptions from strain specific annotations:

  • dihydrolipoyl dehydrogenase
  • Dihydrolipoamide dehydrogenase
  • Dihydrolipoamide dehydrogenase of acetoin dehydrogenase
  • acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase, putative
  • dihydrolipoamide dehydrogenase component E3
  • putative acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase
  • Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component,-like enzyme
• strand^?: -
• coordinates^?: 3049311..3051014
• occurrence^?: in 98% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS05725 (lpdA)
(2)
D39:
SPD_RS05510 (lpdA)
(2)
D39V:
SPV_RS04830 (lpdA)
(19A)
Hungary19A-6:
—
(19F)
EF3030:
EF3030_RS05625 (lpdA)
(6B)^?
670-6B:
SP670_RS05485 (lpdA)
(6A)
6A-10:
HKM25_RS05465 (lpdA)
(5)
70585:
SP70585_RS06045 (lpdA)
(19F)
A026:
T308_RS05610 (lpdA)
(3)
A66:
A66_RS05225 (lpdA)
(11A)
AP200:
SPAP_RS05200 (lpdA)
(12F)
ASP0581:
EL334_RS06040 (lpdA)
(19F)
ATCC 49619:
EL263_RS05695 (lpdA)
(23F)
ATCC 700669:
SPN23F_RS05410 (lpdA)
(19F)
BM6001:
ODS73_RS06145 (lpdA)
(1)
BVJ1JL:
JN057_RS05835 (lpdA)
(14)
CGSP14:
SPCG_RS05885 (lpdA)
(19F)
G54:
SPG_RS05350 (lpdA)
(1)
gamPNI0373:
HMPREF1038_RS05105 (lpdA)
(3)
HU-OH:
EL271_RS05885 (lpdA)
(19A)
Hu15:
SPNHU15_RS05700 (lpdA)
(19A)
Hu17:
SPNHU17_RS05625 (lpdA)
(1)
INV104:
INV104_RS05800 (lpdA)
(14)
INV200:
SPNINV200_RS05705 (lpdA)
(14)
JJA:
SPJ_RS05400 (lpdA)
(19F)
MDRSPN001:
MDRSPN_RS05180 (lpdA)
(1)
NCTC7465:
AT689_RS08240 (lpdA)
(2)
NCTC7466:
DQM66_RS04840 (lpdA)
(4)
NU83127:
EL277_RS05745 (lpdA)
(3)
OXC141:
SPNOXC_RS05635 (lpdA)
(1)
P1031:
SPP_RS05970 (lpdA)
(2)
R6:
SPR_RS05235 (lpdA)
(19A)
SP49:
BMJ42_RS06175 (lpdA)
(1)
SPN032672:
SPN032672_RS00670 (lpdA)
(3)
SPN034156:
SPN034156_RS00690 (lpdA)
(3)
SPN034183:
SPN034183_RS05650 (lpdA)
(3)
SPN994038:
SPN994038_RS05555 (lpdA)
(3)
SPN994039:
SPN994039_RS05560 (lpdA)
(3)
SPNA45:
SPNA45_RS08025 (lpdA)
(19F)
ST556:
MYY_RS06090 (lpdA)
(19F)
Taiwan19F-14:
SPT_RS05880 (lpdA)
(19A)
TCH8431/19A:
HMPREF0837_RS06405 (lpdA)
(4)
Xen35:
CXP32_RS05780 (lpdA)

⊟Genome Viewer

TIGR4
D39
D39V
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEAEEDGYLIAIL
  D39             MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEAEEDGYLIAIL
  D39V            MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEAEEDGYLIAIL
  EF3030          MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEAEEDGYLIAIL
                  ************************************************************
  
  TIGR4           KGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKSDDAFDIVVIGGG
  D39             KGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKSDDAFDIVVIGGG
  D39V            KGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKSDDAFDIVVIGGG
  EF3030          KGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKSDDAFDIVVIGGG
                  **********************************.**********.**************
  
  TIGR4           PAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEIIENIGHAANRGIVI
  D39             PAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEIIENIGHAANRGIVI
  D39V            PAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEIIENIGHAANRGIVI
  EF3030          PAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEIIENIGHAANRGIVI
                  ************************************************************
  
  TIGR4           ENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGTITKDKNVLVNGSELLE
  D39             ENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGTITKDKNVLVNGSELLE
  D39V            ENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGTITKDKNVLVNGSELLE
  EF3030          ENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGTITKDKNVLVNGSELLE
                  ************************************************************
  
  TIGR4           TKKIILAGGSKVNKINVPGMESPLVMTSDDILEMNEVPESLVIIGGGVVGIELGQAFMTF
  D39             TKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLVIIGGGVVGIELGQAFMTF
  D39V            TKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLVIIGGGVVGIELGQAFMTF
  EF3030          TKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLVIIGGGVVGIELGQAFMTF
                  ************.***********************************************
  
  TIGR4           GSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGTKLQEIIEENGQLRIKVEGKD
  D39             GSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGTKLQEIIEENGQLRIKVEGKD
  D39V            GSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGTKLQEIIEENGQLRIKVEGKD
  EF3030          GSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGTKLQEIIEENGQLRIKVEGKD
                  ******************.*****************************************
  
  TIGR4           DIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYMETSVPGIYAPGDINGTKMLAHA
  D39             DIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYMETSVPGIYAPGDINGTKMLAHA
  D39V            DIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYMETSVPGIYAPGDINGTKMLAHA
  EF3030          DIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYMETSVPGIYAPGDINGTKMLAHA
                  ************************************************************
  
  TIGR4           AFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVAAVGLTEEQAREKYDVAIGKFNFAA
  D39             AFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVAAVGLTEEQAREKYDVAIGKFNFAA
  D39V            AFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVAAVGLTEEQAREKYDVAIGKFNFAA
  EF3030          AFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVAAVGLTEEQAREKYDVAIGKFNFAA
                  ************************************************************
  
  TIGR4           NGRAIASDAAQGFVKVIADKKYGEILGVHIIGPAAAELINEASSIIEMEITVEEMLKTIH
  D39             NGRAIASDAAQGFVKVIADKKYGEILGVHIIGPAAAELINEASSIIEMEITVEEMLKTIH
  D39V            NGRAIASDAAQGFVKVIADKKYGEILGVHIIGPAAAELINEASSIIEMEITVEEMLKTIH
  EF3030          NGRAIASDAAQGFVKVIADKKYGEILGVHIIGPAAAELINEASSIIEMEITVEEMLKTIH
                  ************************************************************
  
  TIGR4           GHPTYSEVMYEAFADVLGMAIHSPKKK
  D39             GHPTYSEVMYEAFADVLGMAIHSPKKK
  D39V            GHPTYSEVMYEAFADVLGMAIHSPKKK
  EF3030          GHPTYSEVMYEAFADVLGMAIHSPKKK
                  ***************************