PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002390000
• symbol^?: pdrM
• synonym:
• description^?: sodium-coupled multidrug efflux MATE transporter PdrM

  descriptions from strain specific annotations:

  • sodium-coupled multidrug efflux MATE transporter PdrM
  • MATE efflux family protein
  • putative multidrug resistance protein
  • Multidrug resistance protein NorM
  • putative multidrug resistance protein NorM
  • Dihydrolipoamide acetyltransferase
  • Conserved hypothetical protein
  • MATE family efflux transporter
  • multidrug transporter MatE
  • Na+-driven multidrug efflux pump
• strand^?: -
• coordinates^?: 3054427..3058870
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS05745 (pdrM)
(2)
D39:
SPD_RS05530 (pdrM)
(2)
D39V:
SPV_RS04810 (pdrM)
(19A)
Hungary19A-6:
SPH_RS06190 (pdrM)
(19F)
EF3030:
EF3030_RS05605 (pdrM)
(6B)^?
670-6B:
SP670_RS05465 (pdrM)
(6A)
6A-10:
HKM25_RS05485 (pdrM)
(5)
70585:
SP70585_RS06065 (pdrM)
(19F)
A026:
T308_RS05630 (pdrM)
(3)
A66:
A66_RS05245 (pdrM)
(11A)
AP200:
SPAP_RS05180 (pdrM)
(12F)
ASP0581:
EL334_RS06060 (pdrM)
(19F)
ATCC 49619:
EL263_RS05715 (pdrM)
(23F)
ATCC 700669:
SPN23F_RS05430 (pdrM)
(19F)
BM6001:
ODS73_RS06165 (pdrM)
(1)
BVJ1JL:
JN057_RS05855 (pdrM)
(14)
CGSP14:
SPCG_RS05865 (pdrM)
(19F)
G54:
SPG_RS05370 (pdrM)
(1)
gamPNI0373:
HMPREF1038_RS05085 (pdrM)
(3)
HU-OH:
EL271_RS05905 (pdrM)
(19A)
Hu15:
SPNHU15_RS05720 (pdrM)
(19A)
Hu17:
SPNHU17_RS05645 (pdrM)
(1)
INV104:
INV104_RS05820 (pdrM)
(14)
INV200:
SPNINV200_RS05685 (pdrM)
(14)
JJA:
SPJ_RS05420 (pdrM)
(19F)
MDRSPN001:
MDRSPN_RS05200 (pdrM)
(1)
NCTC7465:
AT689_RS08260 (pdrM)
(2)
NCTC7466:
DQM66_RS04820 (pdrM)
(4)
NU83127:
EL277_RS05765 (pdrM)
(3)
OXC141:
SPNOXC_RS05655 (pdrM)
(1)
P1031:
SPP_RS05990 (pdrM)
(2)
R6:
SPR_RS05255 (pdrM)
(19A)
SP49:
BMJ42_RS06195 (pdrM)
(1)
SPN032672:
SPN032672_RS00690 (pdrM)
(3)
SPN034156:
SPN034156_RS00710 (pdrM)
(3)
SPN034183:
SPN034183_RS05670 (pdrM)
(3)
SPN994038:
SPN994038_RS05575 (pdrM)
(3)
SPN994039:
SPN994039_RS05580 (pdrM)
(3)
SPNA45:
SPNA45_RS08045 (pdrM)
(19F)
ST556:
MYY_RS06110 (pdrM)
(19F)
Taiwan19F-14:
SPT_RS05900 (pdrM)
(19A)
TCH8431/19A:
HMPREF0837_RS06385 (pdrM)
(4)
Xen35:
CXP32_RS05800 (pdrM)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPF
  D39             MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPF
  D39V            MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPF
  Hungary19A-6    MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPF
  EF3030          MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPF
                  ************************************************************
  
  TIGR4           FTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLSVVLLGMVLFLAPIILNHI
  D39             FTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLSVVLLGMVLFLAPTILNHI
  D39V            FTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLSVVLLGMVLFLAPTILNHI
  Hungary19A-6    FTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLSVLLLGLVLFLAPPVLNHI
  EF3030          FTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLSVVLLGMVLFLAPTILNHI
                  *******************************************:***:****** :****
  
  TIGR4           GLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLTKLSMYLMLLLLPLNSGFNYL
  D39             GLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLTKLSMYLMLLLLPLNSGFNYL
  D39V            GLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLTKLSMYLMLLLLPLNSGFNYL
  Hungary19A-6    GLEVPVAVVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLTKLSMYLMLLLLPLNSGFNYL
  EF3030          GLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLTKLSMYLMLLLLPLNSGFNYL
                  ***..**.****************************************************
  
  TIGR4           LIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRIPLNMDKIKEG
  D39             LIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRILLNMDKIKEG
  D39V            LIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRILLNMDKIKEG
  Hungary19A-6    LIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRIPLNMDKIKEG
  EF3030          LIYGAFGIPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRIPLNMDNIKEG
                  *******:****************************************** ****:****
  
  TIGR4           VRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASHQSAMNFSSLMYAFPMSISSAMAIV
  D39             VRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASHQSAMNFSSLMYAFPMSISSAMAIV
  D39V            VRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASHQSAMNFSSLMYAFPMSISSAMAIV
  Hungary19A-6    VRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASHQSAMNFSSLMYAFPMSISSAMAIV
  EF3030          VRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASHQSAMNFSSLMYAFPMSISSAMAIV
                  ****************:************.******************************
  
  TIGR4           VSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTFLYIFRGNVASLYGNDPKFIDLTVRFL
  D39             VSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTFLYIFRGNVASLYGNDPKFIDLTARFL
  D39V            VSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTFLYIFRGNVASLYGNDPKFIDLTARFL
  Hungary19A-6    VSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLSFLYIFRGNVASLYGNDPEFIDLTARFL
  EF3030          VSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTFLYIFRGNVASLYGNDPKFIDLTVRFL
                  ********************************:*****************:*****.***
  
  TIGR4           TYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLLGYWGVAIPVRTLFDSLTDFGAYSYW
  D39             TYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLLGYWGVAIPVATLFDSLTDFGAYSYW
  D39V            TYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLLGYWGVAIPVATLFDSLTDFGAYSYW
  Hungary19A-6    TYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLVGYWGVTLPVAMVFDSLTDFGAYSYW
  EF3030          TYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLLGYWGVAIPVATLFDSLTDFGAYSYW
                  **********************************:*****::**  :*************
  
  TIGR4           IGLIISLIVSGALYRWRLTVIMKRFESLAKSKC
  D39             IGLIISLIVSGALYRWRLTVIMKRFESLAKSKR
  D39V            IGLIISLIVSGALYRWRLTVIMKRFESLAKSKR
  Hungary19A-6    IGLIISLIVSGALYRWRLTVIVKRFES---RKA
  EF3030          IGLIISLIVSGALYRWRLTVIMKRFESLAKSKC
                  *********************:*****    *