PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002445000
• symbol^?: nrdE
• synonym:
• description^?: class 1b ribonucleoside-diphosphate reductase subunit alpha

  descriptions from strain specific annotations:

  • class 1b ribonucleoside-diphosphate reductase subunit alpha
  • ribonucleoside-diphosphate reductase, alpha subunit
  • putative ribonucleoside-diphosphate reductase alpha chain
  • Ribonucleoside-diphosphate reductase subunit
  • ribonucleotide-diphosphate reductase subunit alpha
  • ribonucleoside-diphosphate reductase
  • Ribonucleoside-diphosphate reductase (major subunit)
  • ribonucleoside-diphosphate reductase, alpha subunitv
  • ribonucleoside-diphosphate reductase 2, alpha subunit
  • Ribonucleoside-diphosphate reductase subunit alpha 2
  • ribonucleotide-diphosphate reductase alpha subunit
  • Ribonucleotide reductase, alpha subunit
  • Ribonucleotide reductase of class Ib (aerobic),alpha subunit
  • Ribonucleotide reductase of class Ib (aerobic), beta subunit (pseudogene)
  • Ribonucleotide reductase of class Ib, alpha subunit
• strand^?: +
• coordinates^?: 3030865..3033024
• occurrence^?: in 100% of 41 strains

⊟Orthologs

TIGR4:
SP_RS05810 (nrdE)
D39:
SPD_RS05595 (nrdE)
D39V:
SPV_RS05585 (nrdE)
Hungary19A-6:
SPH_RS06295 (nrdE)
EF3030:
EF3030_RS05535 (nrdE)
670-6B:
SP670_RS05400 (nrdE)
6A-10:
HKM25_RS05555 (nrdE)
70585:
SP70585_RS06140 (nrdE)
A026:
T308_RS04900 (nrdE)
A66:
A66_RS05345 (nrdE)
AP200:
SPAP_RS05975 (nrdE)
ASP0581:
EL334_RS06120 (nrdE)
ATCC 49619:
EL263_RS05785 (nrdE)
ATCC 700669:
SPN23F_RS05490 (nrdE)
BVJ1JL:
JN057_RS05920 (nrdE)
CGSP14:
SPCG_RS05795 (nrdE)
G54:
SPG_RS05430 (nrdE)
gamPNI0373:
HMPREF1038_RS05855 (nrdE)
HU-OH:
EL271_RS05965 (nrdE)
Hu15:
SPNHU15_RS05790 (nrdE)
Hu17:
SPNHU17_RS05715 (nrdE)
INV104:
INV104_RS05885 (nrdE)
INV200:
SPNINV200_RS05625 (nrdE)
JJA:
SPJ_RS05480 (nrdE)
MDRSPN001:
MDRSPN_RS04485 (nrdE)
NCTC7466:
DQM66_RS05595 (nrdE)
NU83127:
EL277_RS05830 (nrdE)
OXC141:
SPNOXC_RS05715 (nrdE)
P1031:
SPP_RS06060 (nrdE)
R6:
SPR_RS05320 (nrdE)
SP49:
BMJ42_RS06260 (nrdE)
SPN032672:
SPN032672_RS00755 (nrdE)
SPN034156:
SPN034156_RS00770 (nrdE)
SPN034183:
SPN034183_RS05730 (nrdE)
SPN994038:
SPN994038_RS05635 (nrdE)
SPN994039:
SPN994039_RS05640 (nrdE)
SPNA45:
SPNA45_RS08105 (nrdE)
ST556:
MYY_RS05370 (nrdE)
Taiwan19F-14:
SPT_RS05160 (nrdE)
TCH8431/19A:
HMPREF0837_RS06325 (nrdE)
Xen35:
CXP32_RS05865 (nrdE)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYL
  D39             MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYL
  D39V            MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYL
  Hungary19A-6    MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYL
  EF3030          MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYL
                  ************************************************************
  
  TIGR4           IEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLENM
  D39             IEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLENM
  D39V            IEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLENM
  Hungary19A-6    IEHNYIETAFIKKYRPEFLEELSQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLESM
  EF3030          IEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLENM
                  **********************:***********************************.*
  
  TIGR4           EDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLNAGRARRGELVSCFLIQVTDD
  D39             EDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLNAGRARRGELVSCFLIQVTDD
  D39V            EDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLNAGRARRGELVSCFLIQVTDD
  Hungary19A-6    EDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLNAGRARRGELVSCFLIQVTDD
  EF3030          EDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLNAGRARRGELVSCFLIQVTDD
                  ************************************************************
  
  TIGR4           MNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
  D39             MNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
  D39V            MNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
  Hungary19A-6    MNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
  EF3030          MNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
                  ************************************************************
  
  TIGR4           QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEM
  D39             QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEM
  D39V            QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEM
  Hungary19A-6    QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEM
  EF3030          QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEM
                  ************************************************************
  
  TIGR4           YLFSPYSVEKEYGVPFNYIDITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYV
  D39             YLFSPYSVEKEYGVPFNYIDITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYV
  D39V            YLFSPYSVEKEYGVPFNYIDITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYV
  Hungary19A-6    YLFSPYSVEKEYNVPFNYIDITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYV
  EF3030          YLFSPYSVEKEYGVPFNYIDITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYV
                  ************.***********************************************
  
  TIGR4           VNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEFLQMGTDVSCNLGSTNVVNMM
  D39             VNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEFLQMGTDVSCNLGSTNVVNMM
  D39V            VNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEFLQMGTDVSCNLGSTNVVNMM
  Hungary19A-6    VNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEFLQMGTDVSCNLGSTNVVNMM
  EF3030          VNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEFLQMGTDVSCNLGSTNVVNMM
                  ************************************************************
  
  TIGR4           TSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
  D39             TSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
  D39V            TSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
  Hungary19A-6    TSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
  EF3030          TSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG
                  ************************************************************
  
  TIGR4           SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANGSYFDKYVTGEFVPTS
  D39             SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANGSYFDKYVTGEFVPTS
  D39V            SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANGSYFDKYVTGEFVPTS
  Hungary19A-6    SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYAKGSYFDKYVTGEFVPKS
  EF3030          SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYANGSYFDKYVTGEFVPTS
                  *******************************************:**************.*
  
  TIGR4           DRVKELFKNVFIPGVADWAELRDKVQEDGLYHQNRLAVAPNGSISYINDVSASIHPITQR
  D39             DRVKELFKNVFIPGVADWAELRDKVQEDGLYHQNRLAVAPNGSISYINDVSASIHPITQR
  D39V            DRVKELFKNVFIPGVADWAELRDKVQEDGLYHQNRLAVAPNGSISYINDVSASIHPITQR
  Hungary19A-6    DRVKELFKDVFIPSAADWAELRDKVQADGLYHQNRLAVAPNGSISYINDVSASIHPITQR
  EF3030          DRVKELFKNVFIPGVADWAELRDKVQEDGLYHQNRLAVAPNGSISYINDVSASIHPITQR
                  ********:****..*********** *********************************
  
  TIGR4           IEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMR
  D39             IEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMR
  D39V            IEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMR
  Hungary19A-6    IEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMR
  EF3030          IEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMR
                  ************************************************************
  
  TIGR4           SDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI
  D39             SDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI
  D39V            SDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI
  Hungary19A-6    SDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI
  EF3030          SDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI
                  ***********************************************************