PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN002528000
• symbol^?: carB
• synonym:
• description^?: carbamoyl-phosphate synthase large subunit

  descriptions from strain specific annotations:

  • carbamoyl-phosphate synthase large subunit
  • carbamoyl-phosphate synthase large chain
  • carbamoyl-phosphate synthase, large subunit
  • carbamoyl-phosphate synthase%2C large subunit
  • Carbamoylphosphate synthase (ammonia), heavy subunit
  • Carbamoyl-phosphate synthase large chain CarB
  • carbamoyl-phosphate synthase pyrimidine-specific large chain
• strand^?: -
• coordinates^?: 3236333..3239509
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS06250 (carB)
(2)
D39:
SPD_RS06035 (carB)
(2)
D39V:
SPV_RS06030 (carB)
(19A)
Hungary19A-6:
SPH_RS06730 (carB)
(19F)
EF3030:
EF3030_RS06125 (carB)
(6B)^?
670-6B:
SP670_RS04945 (carB)
(6A)
6A-10:
HKM25_RS05980 (carB)
(5)
70585:
SP70585_RS06645 (carB)
(19F)
A026:
T308_RS04455 (carB)
(3)
A66:
A66_RS05805 (carB)
(11A)
AP200:
SPAP_RS06430 (carB)
(12F)
ASP0581:
EL334_RS06575 (carB)
(19F)
ATCC 49619:
EL263_RS06215 (carB)
(23F)
ATCC 700669:
SPN23F_RS05925 (carB)
(19F)
BM6001:
ODS73_RS06650 (carB)
(1)
BVJ1JL:
JN057_RS06350 (carB)
(14)
CGSP14:
SPCG_RS06415 (carB)
(19F)
G54:
SPG_RS05865 (carB)
(1)
gamPNI0373:
HMPREF1038_RS06275 (carB)
(3)
HU-OH:
EL271_RS06385 (carB)
(19A)
Hu15:
SPNHU15_RS06195 (carB)
(19A)
Hu17:
SPNHU17_RS06125 (carB)
(1)
INV104:
INV104_RS06315 (carB)
(14)
INV200:
SPNINV200_RS06230 (carB)
(14)
JJA:
SPJ_RS05910 (carB)
(19F)
MDRSPN001:
MDRSPN_RS04055 (carB)
(1)
NCTC7465:
AT689_RS07560 (carB)
(2)
NCTC7466:
DQM66_RS06035 (carB)
(4)
NU83127:
EL277_RS06270 (carB)
(3)
OXC141:
SPNOXC_RS06150 (carB)
(1)
P1031:
SPP_RS06490 (carB)
(2)
R6:
SPR_RS05760 (carB)
(19A)
SP49:
BMJ42_RS06700 (carB)
(1)
SPN032672:
SPN032672_RS01185 (carB)
(3)
SPN034156:
SPN034156_RS01205 (carB)
(3)
SPN034183:
SPN034183_RS06165 (carB)
(3)
SPN994038:
SPN994038_RS06070 (carB)
(3)
SPN994039:
SPN994039_RS06075 (carB)
(3)
SPNA45:
SPNA45_RS05150 (carB)
(19F)
ST556:
MYY_RS04930 (carB)
(19F)
Taiwan19F-14:
SPT_RS04715 (carB)
(19A)
TCH8431/19A:
HMPREF0837_RS05880 (carB)
(4)
Xen35:
CXP32_RS06310 (carB)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEI
  D39             MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEI
  D39V            MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEI
  Hungary19A-6    MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEI
  EF3030          MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEI
                  ************************************************************
  
  TIGR4           ADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKL
  D39             ADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKL
  D39V            ADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKL
  Hungary19A-6    ADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMELSKNGILDELGVEFLGTRL
  EF3030          ADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKL
                  ********************* ********************************:***:*
  
  TIGR4           SAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGG
  D39             SAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGG
  D39V            SAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGG
  Hungary19A-6    SAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAATIGYPVIVRPAFTLGGTGGG
  EF3030          SAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGG
                  ***********************************:************************
  
  TIGR4           MCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPV
  D39             MCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPV
  D39V            MCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPV
  Hungary19A-6    MCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPV
  EF3030          MCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPV
                  ************************************************************
  
  TIGR4           GIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVN
  D39             GIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVN
  D39V            GIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVN
  Hungary19A-6    GIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVN
  EF3030          GIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVN
                  ************************************************************
  
  TIGR4           PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRF
  D39             PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRF
  D39V            PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRF
  Hungary19A-6    PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRF
  EF3030          PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRF
                  ************************************************************
  
  TIGR4           PFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDAL
  D39             PFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDAL
  D39V            PFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDAL
  Hungary19A-6    PFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDAL
  EF3030          PFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDTL
                  **********************************************************:*
  
  TIGR4           IEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLE
  D39             IEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLE
  D39V            IEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLE
  Hungary19A-6    IEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLE
  EF3030          IEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLE
                  ************************************************************
  
  TIGR4           VLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTY
  D39             VLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTY
  D39V            VLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTY
  Hungary19A-6    VLKTAKLNGFSDRKIAELWGTTDDQVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTY
  EF3030          VLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTY
                  ************************:***********************************
  
  TIGR4           GWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVST
  D39             GWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVST
  D39V            GWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVST
  Hungary19A-6    GWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVST
  EF3030          GWENESIKSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVST
                  *******:****************************************************
  
  TIGR4           DFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVAD
  D39             DFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVAD
  D39V            DFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVAD
  Hungary19A-6    DFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVAD
  EF3030          DFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVAD
                  ************************************************************
  
  TIGR4           LDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIV
  D39             LDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIV
  D39V            LDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIV
  Hungary19A-6    LDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIV
  EF3030          LDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIV
                  ************************************************************
  
  TIGR4           ENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHS
  D39             ENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHS
  D39V            ENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHS
  Hungary19A-6    ENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHS
  EF3030          ENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHS
                  ************************************************************
  
  TIGR4           GDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRT
  D39             GDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRT
  D39V            GDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRT
  Hungary19A-6    GDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRT
  EF3030          GDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRT
                  ************************************************************
  
  TIGR4           VPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLL
  D39             VPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLL
  D39V            VPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLL
  Hungary19A-6    VPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLL
  EF3030          VPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLL
                  ************************************************************
  
  TIGR4           GPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNI
  D39             GPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNI
  D39V            GPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNI
  Hungary19A-6    GPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNI
  EF3030          GPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNI
                  ************************************************************
  
  TIGR4           GYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDG
  D39             GYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDG
  D39V            GYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDG
  Hungary19A-6    GYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDG
  EF3030          GYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDG
                  ************************************************************
  
  TIGR4           EQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
  D39             EQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
  D39V            EQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
  Hungary19A-6    EQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
  EF3030          EQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
                  **************************************