PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN003089000
• symbol^?: pbp2b
• synonym:
• description^?: penicillin-binding protein 2B

  descriptions from strain specific annotations:

  • penicillin-binding protein 2B
  • penicillin-binding protein PBP2B
  • penicillin-binding protein 2
  • Cell division protein FtsI/penicillin-binding protein 2
  • Cell division protein FtsI [Peptidoglycan synthetase]
  • penicillin-binding protein
  • penicillin-binding protein, transpeptidase domain protein
  • penicillin binding transpeptidase domain protein
• strand^?: -
• coordinates^?: 4000620..4002678
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS08265 (pbp2b)
(2)
D39:
SPD_RS07895 (pbp2b)
(2)
D39V:
SPV_RS07890 (pbp2b)
(19A)
Hungary19A-6:
SPH_RS08675 (pbp2b)
(19F)
EF3030:
EF3030_RS07880 (pbp2b)
(6B)^?
670-6B:
SP670_RS08725 (pbp2b)
(6A)
6A-10:
HKM25_RS08355 (pbp2b)
(5)
70585:
SP70585_RS08500 (pbp2b)
(19F)
A026:
T308_RS07795 (pbp2b)
(3)
A66:
A66_RS07490 (pbp2b)
(11A)
AP200:
SPAP_RS08305 (pbp2b)
(12F)
ASP0581:
EL334_RS08530 (pbp2b)
(19F)
ATCC 49619:
EL263_RS08085 (pbp2b)
(23F)
ATCC 700669:
SPN23F_RS08440 (pbp2b)
(19F)
BM6001:
ODS73_RS08775 (pbp2b)
(1)
BVJ1JL:
JN057_RS08070 (pbp2b)
(14)
CGSP14:
SPCG_RS08520 (pbp2b)
(19F)
G54:
SPG_RS07895 (pbp2b)
(1)
gamPNI0373:
HMPREF1038_RS08110 (pbp2b)
(3)
HU-OH:
EL271_RS08195 (pbp2b)
(19A)
Hu15:
SPNHU15_RS00635 (pbp2b)
(19A)
Hu17:
SPNHU17_RS07940 (pbp2b)
(1)
INV104:
INV104_RS08195 (pbp2b)
(14)
INV200:
SPNINV200_RS07975 (pbp2b)
(14)
JJA:
SPJ_RS07780 (pbp2b)
(19F)
MDRSPN001:
MDRSPN_RS02775 (pbp2b)
(1)
NCTC7465:
AT689_RS05795 (pbp2b)
(2)
NCTC7466:
DQM66_RS07890 (pbp2b)
(4)
NU83127:
EL277_RS08330 (pbp2b)
(3)
OXC141:
SPNOXC_RS07965 (pbp2b)
(1)
P1031:
SPP_RS08330 (pbp2b)
(2)
R6:
SPR_RS07525 (pbp2b)
(19A)
SP49:
BMJ42_RS08860 (pbp2b)
(1)
SPN032672:
SPN032672_RS03085 (pbp2b)
(3)
SPN034156:
SPN034156_RS03030 (pbp2b)
(3)
SPN034183:
SPN034183_RS07990 (pbp2b)
(3)
SPN994038:
SPN994038_RS07890 (pbp2b)
(3)
SPN994039:
SPN994039_RS07895 (pbp2b)
(3)
SPNA45:
SPNA45_RS03275 (pbp2b)
(19F)
ST556:
MYY_RS08225 (pbp2b)
(19F)
Taiwan19F-14:
SPT_RS08015 (pbp2b)
(19A)
TCH8431/19A:
HMPREF0837_RS09165 (pbp2b)
(4)
Xen35:
CXP32_RS08340 (pbp2b)

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKIT
  D39             MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKIT
  D39V            MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKIT
  Hungary19A-6    MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKIT
  EF3030          MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASASQTKIT
                  ************************************************************
  
  TIGR4           SSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQ
  D39             SSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQ
  D39V            SSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQ
  Hungary19A-6    SSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQ
  EF3030          SSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETAKKLLTYVSISSPNLTERQ
                  ************************************************************
  
  TIGR4           LADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNNAVDSVQTSQLNYTEDEKKEI
  D39             LADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNNAVDSVQTSQLNYTEDEKKEI
  D39V            LADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNNAVDSVQTSQLNYTEDEKKEI
  Hungary19A-6    LADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNNAVDSVQTSQLNYTEDEKKEI
  EF3030          LADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNNVVDSVQTSQLNYTEDEKKEI
                  ************** *************************.*******************
  
  TIGR4           YLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG
  D39             YLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG
  D39V            YLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG
  Hungary19A-6    YLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKILETSLSSIVG
  EF3030          YLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMPGISISTSWDRKVLETSLSSIVG
                  *************************************************:**********
  
  TIGR4           SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMES
  D39             SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMES
  D39V            SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMES
  Hungary19A-6    SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMES
  EF3030          SVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQYEETLQGKRSVKEIHLDKYGNMES
                  ************************************************************
  
  TIGR4           VDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAV
  D39             VDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAV
  D39V            VDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAV
  Hungary19A-6    VDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELGNGGAKYSEGVYAVALNPKTGAV
  EF3030          VDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFNSELENGGAKYSEGVYAVALNPKTGAV
                  ************************************* **********************
  
  TIGR4           LSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVF
  D39             LSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVF
  D39V            LSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVF
  Hungary19A-6    LSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVF
  EF3030          LSMSGIKHDLKTGELTPDSLGTVTNVFVPGSVVKAATISSGWENGVLSGNQTLTDQSIVF
                  ************************************************************
  
  TIGR4           QGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAM
  D39             QGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAM
  D39V            QGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAM
  Hungary19A-6    QGSAPINSWYPAFSVPTPITAVQALEYSSNAYMIKTVLGLMGQTYQPNMFVGTSNLESAM
  EF3030          QGSAPINSWYTQAYGSFPITAVQALEYSSNTYMVQTALGLMGQTYQPNMFVGTSNLESAM
                  **********.    . *************:**::*.***********************
  
  TIGR4           EKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATI
  D39             EKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATI
  D39V            EKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATI
  Hungary19A-6    GKLRSTFGEYGLGSATGIDLPDESTGFVPKDYSFANYITNAFGQFDNYTPMQLAQYVATI
  EF3030          EKLRSTFGEYGLGTATGIDLPDESTGFVPKEYSFANYITNAFGQFDNYTPMQLAQYVATI
                   ************:****************:*****************************
  
  TIGR4           ANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGT
  D39             ANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGT
  D39V            ANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGT
  Hungary19A-6    ANDGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGT
  EF3030          ANNGVRVAPRIVEGIYGNNDKGGLGDLIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGT
                  **:*********************************************************
  
  TIGR4           SGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNT
  D39             SGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNT
  D39V            SGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNT
  Hungary19A-6    SGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNT
  EF3030          SGLTTGRAFSNGALVSISGKTGTAESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNT
                  ************************************************************
  
  TIGR4           NLTNGVGPSIARDIINLYQKYHPMN
  D39             NLTNGVGPSIARDIINLYQKYHPMN
  D39V            NLTNGVGPSIARDIINLYQKYHPMN
  Hungary19A-6    NLTNGVGPSIARDIINLYQKYHPMN
  EF3030          NLTNGVGPSIARDIINLYQKYHPMN
                  *************************