PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

⊟Summary

• pan ID^?: PNEUPAN003617000
• symbol^?: cof
• synonym:
• description^?: Cof-type HAD-IIB family hydrolase

  descriptions from strain specific annotations:

  • Cof-type HAD-IIB family hydrolase
  • Cof family protein
  • haloacid dehalogenase-like hydrolase
  • alanine aminotransferase
  • Putative bifunctional
  • Conserved hypothetical protein
  • Cof-like hydrolase
  • cof-like hydrolase family protein
  • HMP-PP phosphatase
  • Hydrolase (HAD superfamily)
  • Hydrolase, HAD superfamily
  • Predicted hydrolases of the HAD superfamily
  • pseudogene
• strand^?: -
• coordinates^?: 4744510..4745899
• occurrence^?: in 100% of 43 strains

⊟Orthologs

(4)^?
TIGR4:
SP_RS10035
(2)
D39:
SPD_RS09555
(2)
D39V:
SPV_RS09550
(19A)
Hungary19A-6:
SPH_RS10465
(19F)
EF3030:
EF3030_RS09705
(6B)^?
670-6B:
SP670_RS10450
(6A)
6A-10:
HKM25_RS10010
(5)
70585:
SP70585_RS10280
(19F)
A026:
T308_RS09570
(3)
A66:
A66_RS08995
(11A)
AP200:
SPAP_RS09950
(12F)
ASP0581:
EL334_RS10235
(19F)
ATCC 49619:
EL263_RS09785
(23F)
ATCC 700669:
SPN23F_RS10290
(19F)
BM6001:
ODS73_RS10370
(1)
BVJ1JL:
JN057_RS09710
(14)
CGSP14:
SPCG_RS10280
(19F)
G54:
SPG_RS09500
(1)
gamPNI0373:
HMPREF1038_RS09715
(3)
HU-OH:
EL271_RS09840
(19A)
Hu15:
SPNHU15_RS09510
(19A)
Hu17:
SPNHU17_RS09500
(1)
INV104:
INV104_RS09960
(14)
INV200:
SPNINV200_RS09690
(14)
JJA:
SPJ_RS09875
(19F)
MDRSPN001:
MDRSPN_RS09395
(1)
NCTC7465:
AT689_RS04035
(2)
NCTC7466:
DQM66_RS09550
(4)
NU83127:
EL277_RS10225
(3)
OXC141:
SPNOXC_RS09615
(1)
P1031:
SPP_RS09955
(2)
R6:
SPR_RS09090
(19A)
SP49:
BMJ42_RS10705
(1)
SPN032672:
SPN032672_RS05880
(3)
SPN034156:
SPN034156_RS04615
(3)
SPN034183:
SPN034183_RS09635
(3)
SPN994038:
SPN994038_RS09540
(3)
SPN994039:
SPN994039_RS09545
(3)
SPNA45:
SPNA45_RS01365
(19F)
ST556:
MYY_RS09990
(19F)
Taiwan19F-14:
SPT_RS09790
(19A)
TCH8431/19A:
HMPREF0837_RS10955
(4)
Xen35:
CXP32_RS10165

⊟Genome Viewer

TIGR4
D39
D39V
Hungary19A-6
EF3030

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  TIGR4           MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLD
  D39             MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLD
  D39V            MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLD
  EF3030          MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATGRGPFFVKELMDDLDLD
                  ************************************************************
  
  TIGR4           FAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLG
  D39             FAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLG
  D39V            FAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLG
  EF3030          FAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIALGTKDAMLGSKIMSFGLG
                  ************************************************************
  
  TIGR4           SFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHLMNQPIYQVLMLMTPEESEKA
  D39             SFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHLMNQPIYQVLMLMTPEESEKA
  D39V            SFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHLMNQPIYQVLMLMTPEESEKA
  EF3030          SFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHLMNQPIYQVLMLMTPEESEKA
                  ************************************************************
  
  TIGR4           AADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
  D39             AADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
  D39V            AADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
  EF3030          AADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYGFDLNQVMAFGDSDNDLEMLAGV
                  ************************************************************
  
  TIGR4           GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHH
  D39             GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHH
  D39V            GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHH
  EF3030          GMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHFGVLSSEKVFVSRDYHFNKVKTFHH
                  ************************************************************
  
  TIGR4           MMDERTQEEPRAWDLEGATHRAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAADK
  D39             MMDERTQEEPRAWDLEGATHRAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAAGK
  D39V            MMDERTQEEPRAWDLEGATHRAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAAGK
  EF3030          MMDERTQEEPRAWDLEGATHRAGFKIEELVEFVRAASPSEEDFGQAVSQLHQALDKAAGK
                  **********************************************************.*
  
  TIGR4           VAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIFDIVHQANMGKIFPDGKAHFD
  D39             VAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIFDIVHQANMGKIFPDGKAHFD
  D39V            VAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIFDIVHQANMGKIFPDGKAHFD
  EF3030          VAKKTPAQQDLIGQVDALIDTLYFTYGSFVLMGVDPERIFDIVHQANMGKIFPDGKAHFD
                  ************************************************************
  
  TIGR4           PVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
  D39             PVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
  D39V            PVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
  EF3030          PVTHKILKPDNWEEKYAPEPAIKKELQRQLKAYERHKERNKS
                  ******************************************