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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_0267 [new locus tag: SP670_RS01335 ]
  • pan locus tag?: PNEUPAN000920000
  • symbol: SP670_0267
  • pan gene symbol?: spxA2
  • synonym: spx
  • product: regulatory protein spx

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_0267 [new locus tag: SP670_RS01335 ]
  • symbol: SP670_0267
  • product: regulatory protein spx
  • replicon: chromosome
  • strand: +
  • coordinates: 237272..237670
  • length: 399
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGATTAAAATTTATACAGTCTCAAGTTGTACTAGCTGTAAAAAAGCAAAAACCTGGCTC
    AATGCCCACCAGTTAAGTTATAAAGAACAAAACCTTGGTAAAGAAGGAATTACGAGAGAA
    GAATTACTGGATATTCTAACCAAAACAGATAACGGAATAGCCAGCATCGTTTCGTCTAAA
    AATCGCTATGCCAAAGCCCTTGGAGTGGATATTGAAGATTTGAGTGTCAATGAAGTTCTC
    AATCTGATTATGGAAACACCGAGAATTTTAAAGAGCCCAATCCTTGTAGATGAAAAACGC
    CTGCAAGTTGGCTACAAGGAAGACGATATTCGTGCCTTCCTACCACGCTCTGTCCGTAAT
    GTAGAAAATGCAGAAGCACGTTTGCGTGCAGCTCTATAA
    60
    120
    180
    240
    300
    360
    399

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_0267 [new locus tag: SP670_RS01335 ]
  • symbol: SP670_0267
  • description: regulatory protein spx
  • length: 132
  • theoretical pI: 9.11716
  • theoretical MW: 14890.1
  • GRAVY: -0.303788

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, Spx/MgsR family (TIGR01617; HMM-score: 115.7)
    and 8 more
    glutaredoxin-like protein, YruB-family (TIGR02196; HMM-score: 35.2)
    Cellular processes Cellular processes Detoxification arsenate reductase (glutaredoxin) (TIGR00014; EC 1.20.4.1; HMM-score: 30.2)
    glutaredoxin-like protein NrdH (TIGR02194; HMM-score: 23.9)
    Metabolism Energy metabolism Electron transport glutaredoxin 3 (TIGR02181; HMM-score: 23.4)
    glutaredoxin-like protein (TIGR02200; HMM-score: 17.6)
    glutaredoxin-family domain (TIGR02190; HMM-score: 17.1)
    Unknown function General nitrogenase-associated protein (TIGR01616; HMM-score: 14.2)
    Metabolism Energy metabolism Sugars lactaldehyde reductase (TIGR02638; EC 1.1.1.77; HMM-score: 12.5)
  • TheSEED  :
    • Transcriptional regulator SpxA2
    DNA Metabolism DNA uptake, competence Competence in Streptococci  Transcriptional regulator SpxA2
  • PFAM:
    Thioredoxin (CL0172) ArsC; ArsC family (PF03960; HMM-score: 66.5)
    and 1 more
    Glutaredoxin; Glutaredoxin (PF00462; HMM-score: 27.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7939
    • Cytoplasmic Membrane Score: 0.0783
    • Cell wall & surface Score: 0.0081
    • Extracellular Score: 0.1197
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014734
    • TAT(Tat/SPI): 0.000348
    • LIPO(Sec/SPII): 0.011418
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM90344 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLDILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQVGYKEDDIRAFLPRSVRNVENAEARLRAAL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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