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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae 670-6B
- locus tag: SP670_0945 [new locus tag: SP670_RS04670 ]
- pan locus tag?: PNEUPAN002665000
- symbol: SP670_0945
- pan gene symbol?: rpiR
- synonym:
- product: transcriptional regulator, RpiR family
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP670_0945 [new locus tag: SP670_RS04670 ]
- symbol: SP670_0945
- product: transcriptional regulator, RpiR family
- replicon: chromosome
- strand: +
- coordinates: 878991..879800
- length: 810
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP002176 (878991..879800) NCBI
- BioCyc: see SP670_RS04670
- MicrobesOnline:
- PneumoBrowse for strain D39V:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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781ATGTTACTGCAAAAAGAACTAATTCCAATGATAGAAGCTAACTTACCAAATATGGCATAT
GCTGAAAAAGACATTGCTAAATTCTTCTTAAAACAGCAACCTCTGAATGATTATTCATCT
AAAGCATTGTGCGAATACCTTAATGTATCCAAAGCAACATTGACTCGATTTGCGAAAAAA
TGTGGTTTTAAAGGTTTTAGACAATTCATTTTCAAATACCAAGAGATGATTCATGAGAAA
GAAAAGTTGGCATTATATACAGAGGCAACAGAAAAAGTTTTATCCGACTATGAGGAAATG
TTGAGAAAAACTTACACGGTTCTTGATGAAGTTCAACTTGAGCGTATTGCTGAGATGATA
GAAACTGCTGAGCGTGTATATCTCTACGGTAAAGGAAGTTCTGTTCTTGCTTTACAAGAA
ATGAAGATGAGATTTATGCGTCTCGGAGTGATTGGTGAAGTATTATCAGACGAGGATATG
ATTTTGTGGAGTAGCTTACTACTTAATGAAAATTGCCTTGTCATTGGAGCATCCATTTCA
GGTCAAACTGATATTGTACTAGAAGGTCTACAAAAAGCTGCAGATAAAGGCGCTAAAACA
GTTTTAATGACTACAAGAAAATTTGACGAAGAAGATTGTTTCTTTGATGAACTATTGTTA
TTAGCTTCGACCGATCATCTCTCGTATGGCAATCGCATATCACCTCAGTTTCCAATACTT
TTAATTACAGACTGCTTATTCTCTAATTATCTGGAAAGTCCAGAGAGACAATATTATTAC
AATCAAACTATTATCCATAAGGAGGAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP670_0945 [new locus tag: SP670_RS04670 ]
- symbol: SP670_0945
- description: transcriptional regulator, RpiR family
- length: 269
- theoretical pI: 4.73074
- theoretical MW: 31129.9
- GRAVY: -0.169145
⊟Function[edit | edit source]
- TIGRFAM: 6-phospho 3-hexuloisomerase (TIGR03127; EC 5.3.-.-; HMM-score: 48.8)and 5 moreCell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides phosphoheptose isomerase (TIGR00441; EC 5.3.1.28; HMM-score: 15.9)bifunctional phosphoglucose/phosphomannose isomerase (TIGR02128; EC 5.3.1.9; HMM-score: 15.6)Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan N-acetylmuramic acid 6-phosphate etherase (TIGR00274; EC 4.2.1.126; HMM-score: 14.1)Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan glutamine-fructose-6-phosphate transaminase (isomerizing) (TIGR01135; EC 2.6.1.16; HMM-score: 11.4)Central intermediary metabolism Amino sugars glutamine-fructose-6-phosphate transaminase (isomerizing) (TIGR01135; EC 2.6.1.16; HMM-score: 11.4)
- TheSEED :
- Sialic acid utilization regulator, RpiR family
- PFAM: HTH (CL0123) HTH_6; Helix-turn-helix domain, rpiR family (PF01418; HMM-score: 43.3)SIS (CL0067) SIS; SIS domain (PF01380; HMM-score: 37.7)and 4 moreSIS_2; SIS domain (PF13580; HMM-score: 23)HTH (CL0123) HTH_17; Helix-turn-helix domain (PF12728; HMM-score: 16.3)STAND_N (CL0587) Helo_like_N; Fungal N-terminal domain of STAND proteins (PF17111; HMM-score: 13.7)HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 12.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
- genes regulated by RpiR*, TF important in Sialic acid utilization: in TIGR4
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.046562
- TAT(Tat/SPI): 0.000904
- LIPO(Sec/SPII): 0.000726
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: ADM91010 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALCEYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLRKTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDMILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDELLLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V:
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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