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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_2135 [new locus tag: SP670_RS10805 ]
  • pan locus tag?: PNEUPAN000638000
  • symbol: SP670_2135
  • pan gene symbol?:
  • synonym:
  • product: conserved hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP670_2135 [new locus tag: SP670_RS10805 ]
  • symbol: SP670_2135
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1991566..1991865
  • length: 300
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP002176 (1991566..1991865) NCBI
  • BioCyc: see SP670_RS10805
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGCCAATTGAAGAAGCTGAAAAAATCGCTCAAAGTCAGGTAGCTTGGGCGATTTTGTTT
    ATCTTGCTTTTTTTTATTATCATTCGATATCTTATCAAGACTTCGGACAAGCGAGAGAAG
    AAGATTATGGATTTGCACGAGCAATCAAAGGCCGACTCTAATAGACGAGAAGAGCGTTTG
    ATGACTCACCTAGAAAAGACCACTACAGAATTAACCACAATCACTCACACGGTCGGAGAC
    ATTCAAAAAGAAATGGTTCGCATGAACGACCGCATGGAAGAAATCGAAAAAGGAGAATAA
    60
    120
    180
    240
    300

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP670_2135 [new locus tag: SP670_RS10805 ]
  • symbol: SP670_2135
  • description: conserved hypothetical protein
  • length: 99
  • theoretical pI: 5.70961
  • theoretical MW: 11763.6
  • GRAVY: -0.525253

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions AmpG-like permease (TIGR00901; HMM-score: 12.6)
    and 2 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking preprotein translocase, YajC subunit (TIGR00739; HMM-score: 9)
    Cellular processes Cellular processes Adaptations to atypical conditions phage shock protein B (TIGR02976; HMM-score: 7.5)
  • TheSEED  :
    • FIG01118066: hypothetical protein
  • PFAM:
    no clan defined Holin_BhlA; BhlA holin family (PF10960; HMM-score: 24.2)
    and 11 more
    DUF6779; Domain of unknown function (DUF6779) (PF20570; HMM-score: 19)
    DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 17.5)
    DUF1043; Protein of unknown function (DUF1043) (PF06295; HMM-score: 16.1)
    DUF4446; Protein of unknown function (DUF4446) (PF14584; HMM-score: 16.1)
    RR_TM4-6; Ryanodine Receptor TM 4-6 (PF06459; HMM-score: 15.4)
    Uds1; Up-regulated During Septation (PF15456; HMM-score: 14.9)
    GPCR_A (CL0192) 7TM_GPCR_Srv; Serpentine type 7TM GPCR chemoreceptor Srv (PF10323; HMM-score: 14)
    OB (CL0021) NfeD; NfeD-like C-terminal, partner-binding (PF01957; HMM-score: 12.6)
    no clan defined DUF16; Protein of unknown function DUF16 (PF01519; HMM-score: 12.5)
    DUF3450; Protein of unknown function (DUF3450) (PF11932; HMM-score: 9.7)
    GOLD-like (CL0521) EMP24_GP25L; emp24/gp25L/p24 family/GOLD (PF01105; HMM-score: 7.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005835
    • TAT(Tat/SPI): 0.00035
    • LIPO(Sec/SPII): 0.001266
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM92187 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMDLHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]