From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-OCT-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_RS10770 [old locus tag: SP670_2128 ]
  • pan locus tag?: PNEUPAN003609000
  • symbol: SP670_RS10770
  • pan gene symbol?: comGF
  • synonym:
  • product: competence protein ComGF

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP670_RS10770 [old locus tag: SP670_2128 ]
  • symbol: SP670_RS10770
  • product: competence protein ComGF
  • replicon: chromosome
  • strand: -
  • coordinates: 1988428..1988889
  • length: 462
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_014498 (1988428..1988889) NCBI
  • BioCyc: SP670_RS10770 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1858 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTA
    GAATCCCTGCTTGCCCTCATTGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGT
    CAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCGAGCAAAAGGAGTGGCTCTTG
    TTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
    CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGAT
    TTTCGTAAAACCGATGCTAGTGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCA
    GCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTTTCCAGTTTCAAAAAGGCTTA
    GAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA
    60
    120
    180
    240
    300
    360
    420
    462

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP670_RS10770 [old locus tag: SP670_2128 ]
  • symbol: SP670_RS10770
  • description: competence protein ComGF
  • length: 153
  • theoretical pI: 6.5418
  • theoretical MW: 17821.2
  • GRAVY: -0.508497

Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Surface structures type IV pilus modification protein PilV (TIGR02523; HMM-score: 17.2)
    Genetic information processing Protein fate Protein modification and repair type IV pilus modification protein PilV (TIGR02523; HMM-score: 17.2)
    and 2 more
    Cell structure Cell envelope Surface structures prepilin-type N-terminal cleavage/methylation domain (TIGR02532; HMM-score: 13.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking prepilin-type N-terminal cleavage/methylation domain (TIGR02532; HMM-score: 13.3)
  • TheSEED: see SP670_2128
  • PFAM:
    no clan defined ComGF; Putative Competence protein ComGF (PF15980; HMM-score: 86)
    and 1 more
    N_methyl; Prokaryotic N-terminal methylation motif (PF07963; HMM-score: 13.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.077272
    • TAT(Tat/SPI): 0.006739
    • LIPO(Sec/SPII): 0.008773
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000250523 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]