From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_0168 [new locus tag: SP70585_RS00815 ]
  • pan locus tag?: PNEUPAN000787000
  • symbol: sdaAA
  • pan gene symbol?: sdhA
  • synonym:
  • product: L-serine dehydratase, iron-sulfur-dependent, alpha subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_0168 [new locus tag: SP70585_RS00815 ]
  • symbol: sdaAA
  • product: L-serine dehydratase, iron-sulfur-dependent, alpha subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 144016..144888
  • length: 873
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGTTTTATTCTATCAAAGAATTGGTCGAGCAAGCAGATCTGGACTTTCAAGGAAATGTC
    GCAGAACTCATGATTACAACAGAGTTTGAATTGACCGGTCGCGAACGTGAAGAAGTCTTC
    CTTCTCATGGAACGCAATCTGGAAGTTATGAAAGCCTCTGTCCAACTTGGCCTCAATGAA
    AATAAATCTCGTAGTGGCCTGACAGGTGGAGATGCTGCCAAATTGGATCACTACATCGAA
    AACGGAAAAACTCTGTCAGATTATACGATTCTCTCGGCTGCCCGAAATGCCATCGCAGTC
    AATGAACACAATGCCAAAATGGGCTTGGTCTGTGCCACTCCAACCGCTGGAAGTGCTGGC
    TGTCTGCCATCCGTTCTCACTGCTGCTATTGAAAAATTAGACCTCAGCCACGAGCAACAA
    TTGGATTTCCTCTTTGCTGCTGGTGCCTTTGGACTAGTCATCGCAAACAATGCCTCCATC
    TCAGGTGCTGAGGGTGGGTGTCAAGCTGAAGTTGGTTCAGCCTCTGCTATGAGTGCTGCC
    GCCTTGACTCTGGCTGCAGGTGGAACACCTTATCAGGCCAGTCAAGCTATTGCCTTTGTC
    ATTAAAAATATGCTAGGCCTCATCTGTGACCCTGTTGCAGGTTTGGTCGAAGTTCCCTGT
    GTCAAACGTAATGCCATGGGAGCTAGCTTTGCTTTCATCGCAGCAGACATGGCCTTGGCA
    GGTATCGAATCTAAAATCCCTGTGGATGAAGTGATCGATGCCATGTACCAAGTAGGAGCA
    AGCATGCCAACTGCCTTTCGTGAAACAGCTGAAGGTGGACTCGCTACCACCCCTACTGGT
    CGTCGCCTCCAAAAAGAAATTTTCGGAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    873

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_0168 [new locus tag: SP70585_RS00815 ]
  • symbol: SdaAA
  • description: L-serine dehydratase, iron-sulfur-dependent, alpha subunit
  • length: 290
  • theoretical pI: 4.33059
  • theoretical MW: 30378.5
  • GRAVY: 0.198621

⊟Function[edit | edit source]

  • reaction:
    EC 4.3.1.17?  ExPASy
    L-serine ammonia-lyase L-serine = pyruvate + NH3
  • TIGRFAM:
    Metabolism Energy metabolism Amino acids and amines L-serine dehydratase, iron-sulfur-dependent, alpha subunit (TIGR00718; EC 4.3.1.17; HMM-score: 375.4)
    Metabolism Energy metabolism Glycolysis/gluconeogenesis L-serine dehydratase, iron-sulfur-dependent, alpha subunit (TIGR00718; EC 4.3.1.17; HMM-score: 375.4)
    and 2 more
    Metabolism Energy metabolism Amino acids and amines L-serine ammonia-lyase (TIGR00720; EC 4.3.1.17; HMM-score: 200.4)
    Metabolism Energy metabolism Glycolysis/gluconeogenesis L-serine ammonia-lyase (TIGR00720; EC 4.3.1.17; HMM-score: 200.4)
  • TheSEED  :
    • L-serine dehydratase, alpha subunit (EC 4.3.1.17)
    Amino Acids and Derivatives Alanine, serine, and glycine Glycine and Serine Utilization  L-serine dehydratase, alpha subunit (EC 4.3.1.17)
    and 1 more
    Carbohydrates Central carbohydrate metabolism Pyruvate Alanine Serine Interconversions  L-serine dehydratase, alpha subunit (EC 4.3.1.17)
  • PFAM:
    no clan defined SDH_alpha; Serine dehydratase alpha chain (PF03313; HMM-score: 253.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007804
    • TAT(Tat/SPI): 0.004384
    • LIPO(Sec/SPII): 0.000221
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP70585_0168&oldid=29416"