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serotype 4
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EF3030
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serotype 5
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serotype 3
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Hu17
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INV200
serotype 14
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serotype 1
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serotype 2
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serotype 3
SPN034183
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SPN994038
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serotype 3
SPNA45
serotype 3
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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_1308 [new locus tag: SP70585_RS06505 ]
  • pan locus tag?: PNEUPAN002495000
  • symbol: SP70585_1308
  • pan gene symbol?: ybjI
  • synonym:
  • product: Cof family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_1308 [new locus tag: SP70585_RS06505 ]
  • symbol: SP70585_1308
  • product: Cof family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1213269..1214063
  • length: 795
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGACAATTAAACTAGTAGCAACGGATATGGACGGAACCTTCCTAGATGGGAATGGACGC
    TTTGATATGGATCGTCTCAAGTCTCTCTTGGCTTCCTACAAGGAAAAAGGGATTTACTTT
    GCGGTGGCTTCGGGTCGGGGATTTCTGTCTCTGGAAAAATTATTTGCTGGTGTTCGTGAT
    GACATTATTTTCATCGCGGAAAATGGCAGTTTGGTAGAGTATCAAGGTCAGGACTTGTAT
    GAAGCGACTATGTCTCGTGACTTTTATCTGGCAACTTTTGAAAAGCTGAAAACGTCACCT
    TATGTAGATATCAATAAACTGCTCTTGACGGGTAAGAAGGGTTCATATGTTCTAGATACG
    GTTGATGAGACCTATTTGAAAGTGAGTCAGCATTATAATGAAAATATCCAAAAAGTAGCG
    AGTTTGGAAGATATCACAGATGACATTTTCAAATTTACAACCAACTTCACAGAAGAAACG
    CTGGAAGCTGGTGAAGCTTGGGTCAATGATAATGTCCCTGGTGTCAAGGCTATGACAACT
    GGCTTTGAATCTATTGATATTGTTCTGGACTATGTCGATAAGGGTGTAGCTATTGTTGAA
    TTAGCTAAAAAACTTGGTATCACAATGGATCAGGTCATGGCTTTTGGAGACAATCTTAAT
    GACTTACATATGATGCAGGTTGTGGGACATCCTGTAGCTCCTGAAAATGCACGACCTGAA
    ATTTTAGAATTAGCAAAGACTGTGATTGGTCACCATAAGGAACGGTCGGTTATAGCTTAT
    ATGGAGGGCTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    795

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_1308 [new locus tag: SP70585_RS06505 ]
  • symbol: SP70585_1308
  • description: Cof family protein
  • length: 264
  • theoretical pI: 4.45486
  • theoretical MW: 29465.4
  • GRAVY: -0.0943182

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function Enzymes of unknown specificity Cof-like hydrolase (TIGR00099; HMM-score: 153.9)
    and 15 more
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 83)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIB (TIGR01484; HMM-score: 82)
    sucrose-phosphate phosphatase subfamily (TIGR01482; EC 3.1.3.-; HMM-score: 73.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family (TIGR01670; EC 3.1.3.45; HMM-score: 36.8)
    mannosyl-3-phosphoglycerate phosphatase family (TIGR01486; EC 3.1.3.-; HMM-score: 32.5)
    Unknown function General mannosyl-3-phosphoglycerate phosphatase homolog (TIGR02463; EC 3.1.3.-; HMM-score: 29.5)
    sucrose phosphatase (TIGR01485; EC 3.1.3.24; HMM-score: 26.8)
    mannosyl-3-phosphoglycerate phosphatase (TIGR02461; EC 3.1.3.70; HMM-score: 25.1)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IB (TIGR01490; HMM-score: 25)
    phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 24.5)
    Metabolism Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 21.2)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIIA (TIGR01662; HMM-score: 19.2)
    Metabolism Energy metabolism Anaerobic phenylphosphate carboxylase, delta subunit (TIGR02726; HMM-score: 17.5)
    sucrose-phosphate synthase, sucrose phosphatase-like domain (TIGR02471; HMM-score: 16.4)
    Unknown function Enzymes of unknown specificity HAD phosphoserine phosphatase-like hydrolase, family IB (TIGR01488; HMM-score: 16.2)
  • TheSEED  :
    • Hydrolase (HAD superfamily)
  • PFAM:
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 167.4)
    and 4 more
    S6PP; Sucrose-6F-phosphate phosphohydrolase (PF05116; HMM-score: 44.7)
    Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 22.8)
    HAD; haloacid dehalogenase-like hydrolase (PF12710; HMM-score: 15)
    Acid_phosphat_B; HAD superfamily, subfamily IIIB (Acid phosphatase) (PF03767; HMM-score: 7.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9985
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0014
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003061
    • TAT(Tat/SPI): 0.000329
    • LIPO(Sec/SPII): 0.000323
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVASGRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYVDINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEETLEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDNLNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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