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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_1987 [new locus tag: SP70585_RS09870 ]
  • pan locus tag?: PNEUPAN003464000
  • symbol: groL
  • pan gene symbol?: groEL
  • synonym:
  • product: chaperonin GroL

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_1987 [new locus tag: SP70585_RS09870 ]
  • symbol: groL
  • product: chaperonin GroL
  • replicon: chromosome
  • strand: -
  • coordinates: 1833827..1835449
  • length: 1623
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGTCAAAAGAAATTAAATTTTCATCAGATGCCCGTTCAGCTATGGTCCGTGGTGTCGAT
    ATCCTTGCAGACACTGTTAAAGTAACCTTGGGACCAAAAGGTCGCAATGTCGTTCTTGAA
    AAATCATTTGGCTCACCATTGATTACCAATGACGGTGTGACTATTGCCAAAGAAATTGAA
    TTAGAAGACCATTTTGAAAATATGGGTGCCAAATTGGTATCAGAAGTGGCTTCAAAAACC
    AATGATATCGCAGGTGATGGAACTACAACTGCAACTGTTTTGACCCAAGCAATCGTCCGT
    GAAGGAATCAAAAACGTCACAGCAGGTGCAAATCCAATCGGTATTCGTCGTGGGATTGAA
    ACAGCAGTTGCCGCAGCAGTTGAAGCTTTGAAAAACAACGCCATCCCTGTTGCCAATAAA
    GAAGCTATCGCTCAAGTTGCAGCCGTATCTTCTCGTTCTGAAAAAGTTGGTGAGTACATC
    TCTGAAGCAATGGAAAAAGTTGGCAAAGACGGTGTCATCACCATCGAAGAGTCACGTGGT
    ATGGAAACAGAGCTTGAAGTCGTAGAAGGAATGCAGTTTGACCGTGGTTACCTTTCACAG
    TACATGGTGACTGATAGCGAAAAAATGGTGGCTGACCTTGAAAATCCGTACATTTTGATT
    ACAGACAAGAAAATTTCCAATATCCAAGAAATCTTGCCACTTTTGGAAAGCATTCTCCAA
    AGCAATCGTCCACTCTTGATTATTGCGGATGATGTGGATGGCGAGGCTCTTCCAACTCTT
    GTTTTGAACAAGATTCGTGGAACCTTCAACGTAGTAGCAGTCAAGGCACCTGGTTTTGGT
    GACCGTCGCAAAGCCATGCTTGAAGATATCGCCATCTTAACAGGCGGAACAGTTATCACA
    GAAGACCTTGGTCTTGAGTTGAAAGATGCGACAATTGAAGCTCTTGGTCAAGCAGCGAGA
    GTGACCGTGGACAAAGATAGCACGGTTATTGTAGAAGGTGCAGGAAATCCTGAAGCGATT
    TCTCACCGTGTTGCGGTTATCAAGTCTCAAATCGAAACTACAACTTCTGAATTTGACCGT
    GAAAAATTGCAAGAACGCTTGGCCAAATTGTCAGGTGGTGTAGCGGTTATTAAGGTCGGA
    GCCGCAACTGAAACTGAGTTGAAAGAAATGAAACTCCGCATTGAAGATGCCCTCAACGCT
    ACTCGTGCAGCTGTTGAAGAAGGTATTGTTGCAGGTGGTGGAACAGCTCTTGCCAATGTG
    ATTCCAGCTGTTGCTACCTTGGAATTGACAGGAGATGAAGCAACAGGACGTAATATTGTT
    CTCCGTGCTTTGGAAGAACCCGTTCGTCAAATTGCTCACAATGCAGGATTTGAAGGATCT
    ATCGTTATCGATCGTTTGAAAAATGCTGAGCTTGGTATAGGATTCAACGCAGCAACTGGC
    GAGTGGGTTAACATGATTGATCAAGGTATCATTGATCCAGTTAAAGTGAGTCGTTCAGCC
    CTACAAAATGCAGCATCTGTAGCCAGCTTGATTTTGACAACAGAAGCAGTCGTAGCCAAT
    AAACCAGAACCAGTAGCCCCAGCTCCAGCAATGGATCCAAGTATGATGGGCGGGATGATG
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1623

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_1987 [new locus tag: SP70585_RS09870 ]
  • symbol: GroL
  • description: chaperonin GroL
  • length: 540
  • theoretical pI: 4.47782
  • theoretical MW: 57095
  • GRAVY: 0.0451852

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein folding and stabilization chaperonin GroL (TIGR02348; HMM-score: 837.4)
    and 9 more
    Genetic information processing Protein fate Protein folding and stabilization thermosome, various subunits, archaeal (TIGR02339; HMM-score: 116.2)
    T-complex protein 1, beta subunit (TIGR02341; HMM-score: 87.3)
    T-complex protein 1, eta subunit (TIGR02345; HMM-score: 83.2)
    T-complex protein 1, delta subunit (TIGR02342; HMM-score: 83.1)
    T-complex protein 1, zeta subunit (TIGR02347; HMM-score: 77.9)
    T-complex protein 1, epsilon subunit (TIGR02343; HMM-score: 69.7)
    T-complex protein 1, gamma subunit (TIGR02344; HMM-score: 66.7)
    T-complex protein 1, theta subunit (TIGR02346; HMM-score: 51.5)
    T-complex protein 1, alpha subunit (TIGR02340; HMM-score: 47.7)
  • TheSEED  :
    • Chaperonin GroEL (EC 5.6.1.7)
    Protein Metabolism Protein folding GroEL GroES  Heat shock protein 60 family chaperone GroEL
  • PFAM:
    no clan defined Cpn60_TCP1; TCP-1/cpn60 chaperonin family (PF00118; HMM-score: 343.6)
    and 1 more
    Ferritin (CL0044) DUF4142; Domain of unknown function (DUF4142) (PF13628; HMM-score: 13.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9595
    • Cytoplasmic Membrane Score: 0.0011
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.0386
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004271
    • TAT(Tat/SPI): 0.000531
    • LIPO(Sec/SPII): 0.000712
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGIKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYISEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYILITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGAGNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQIAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVASLILTTEAVVANKPEPVAPAPAMDPSMMGGMM

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CtsR* (repression) regulon, HrcA (repression) regulon
    CtsR*(TF)important in Heat shock response; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    HrcA(TF)important in Heat shock response; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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