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serotype 4
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D39V
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serotype 19A
EF3030
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serotype 6B
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70585
serotype 5
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serotype 19F
A66
serotype 3
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Hu17
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serotype 14
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serotype 19F
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serotype 1
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serotype 2
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serotype 19A
SPN032672
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serotype 3
SPN034183
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SPN994038
serotype 3
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serotype 3
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serotype 3
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serotype 19F
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serotype 19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS04190 [old locus tag: SP70585_0849 ]
  • pan locus tag?: PNEUPAN001755000
  • symbol: SP70585_RS04190
  • pan gene symbol?: thiJ
  • synonym:
  • product: DJ-1 family glyoxalase III

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS04190 [old locus tag: SP70585_0849 ]
  • symbol: SP70585_RS04190
  • product: DJ-1 family glyoxalase III
  • replicon: chromosome
  • strand: +
  • coordinates: 777028..777582
  • length: 555
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGTAAAAGTAGCAGTTATGTTAGCTCAGGGCTTTGAAGAAATTGAAGCCTTGACAGTT
    GTAGATGTCTTGCGTCGAGCCAATATCACATGTGATATGGTTGGTTTTGAAGAGCAAGTA
    ACGGGTTCGCATGCAATCCAAGTAAGAGCAGATCATGTCTTTGATGGAGATTTATCAGAC
    TATGATATGATTGTTCTTCCTGGAGGTATGCCTGGTTCTGCACATTTACGTGATAATCAG
    ACCTTGATTCAAGAATTGCAAAGCTTCGAGCAAGAAGGGAAGAAACTAGCAGCCATTTGT
    GCGGCACCAATTGCCCTCAATCAAGCAGAGATATTGAAAAATAAGCGATACACTTGTTAT
    GACGGCGTTCAAGAGCAAATCCTTGATGGTCACTACGTCAAGGAAACAGTAGTGGTAGAT
    GGTCAGTTGACAACCAGTCGGGGTCCTTCAACAGCCCTTGCCTTTGCCTACGAGTTGGTG
    GAGCAACTAGGAGGGGACGCAGAGAGTTTACGAACAGGAATGCTCTATCGAGATGTCTTT
    GGTAAAAATCAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    555

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS04190 [old locus tag: SP70585_0849 ]
  • symbol: SP70585_RS04190
  • description: DJ-1 family glyoxalase III
  • length: 184
  • theoretical pI: 4.39248
  • theoretical MW: 20181.8
  • GRAVY: -0.0869565

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General DJ-1 family protein (TIGR01383; HMM-score: 211.8)
    and 5 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides intracellular protease, PfpI family (TIGR01382; HMM-score: 92.4)
    Metabolism Energy metabolism Other malonate decarboxylase holo-[acyl-carrier-protein] synthase (TIGR03135; EC 2.7.7.66; HMM-score: 16)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridoxine pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 (TIGR03800; EC 2.6.-.-; HMM-score: 15)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis phosphoribosylformylglycinamidine synthase I (TIGR01737; EC 6.3.5.3; HMM-score: 14.4)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin cobyrinic acid a,c-diamide synthase (TIGR00379; EC 6.3.1.-; HMM-score: 13.8)
  • TheSEED: see SP70585_0849
  • PFAM:
    Glutaminase_I (CL0014) DJ-1_PfpI; DJ-1/PfpI family (PF01965; HMM-score: 144.5)
    and 3 more
    GATase_3; CobB/CobQ-like glutamine amidotransferase domain (PF07685; HMM-score: 22.3)
    NTP_transf (CL0260) MdcG; Phosphoribosyl-dephospho-CoA transferase MdcG (PF10620; HMM-score: 14.5)
    Glutaminase_I (CL0014) ThiJ_like; ThiJ/PfpI family-like (PF17124; HMM-score: 13.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.999
    • Cytoplasmic Membrane Score: 0.0006
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0004
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010131
    • TAT(Tat/SPI): 0.000406
    • LIPO(Sec/SPII): 0.001299
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSHAIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAAPIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELVEQLGGDAESLRTGMLYRDVFGKNQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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