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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 15-DEC-2024
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae 70585
- locus tag: SP70585_RS06330 [old locus tag: SP70585_1271 ]
- pan locus tag?: PNEUPAN002464000
- symbol: SP70585_RS06330
- pan gene symbol?: vicX
- synonym:
- product: MBL fold metallo-hydrolase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP70585_RS06330 [old locus tag: SP70585_1271 ]
- symbol: SP70585_RS06330
- product: MBL fold metallo-hydrolase
- replicon: chromosome
- strand: -
- coordinates: 1180006..1180815
- length: 810
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012468 (1180006..1180815) NCBI
- BioCyc: SP70585_RS06330 BioCyc
- MicrobesOnline: see SP70585_1271
- PneumoBrowse for strain D39V: SPV_1083 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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781ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTT
TATCTGGAAACCTCAAAAAAGAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATT
ACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACCTGGATGCCATCTTGATTACC
CATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTG
GATTCTTCGCAAAAGCATATTTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGAC
ATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGCAGTTCTATCGCTTTATGAAG
GATGATAAGAGTTTTGTCCTCTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGA
TCAGGTTCTTACGCTTGGCGCCTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCT
AACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAAATCGTACTAAGAAGATTTAC
CTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCA
GATACCGCAACACCATTGACAGAGATATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP70585_RS06330 [old locus tag: SP70585_1271 ]
- symbol: SP70585_RS06330
- description: MBL fold metallo-hydrolase
- length: 269
- theoretical pI: 6.18172
- theoretical MW: 29916.7
- GRAVY: -0.342379
⊟Function[edit | edit source]
- reaction: EC 3.-.-.-? ExPASy
- TIGRFAM: Cellular processes Detoxification hydroxyacylglutathione hydrolase (TIGR03413; EC 3.1.2.6; HMM-score: 34.6)Transcription RNA processing ribonuclease Z (TIGR02651; EC 3.1.26.11; HMM-score: 34)and 8 morephosphonate metabolism protein PhnP (TIGR03307; HMM-score: 26.3)arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein (TIGR03675; HMM-score: 25.7)Unknown function Enzymes of unknown specificity quinoprotein relay system zinc metallohydrolase 2 (TIGR04559; EC 3.-.-.-; HMM-score: 17.9)Transcription Degradation of RNA beta-CASP ribonuclease, RNase J family (TIGR00649; EC 3.1.-.-; HMM-score: 17.3)Unknown function Enzymes of unknown specificity quinoprotein relay system zinc metallohydrolase 1 (TIGR04558; HMM-score: 17.2)Regulatory functions DNA interactions heavy metal response regulator (TIGR01387; HMM-score: 15.8)Cellular processes DNA transformation DNA internalization-related competence protein ComEC/Rec2 (TIGR00361; HMM-score: 12.1)Biosynthesis of cofactors, prosthetic groups, and carriers Other coenzyme PQQ biosynthesis protein B (TIGR02108; HMM-score: 12)
- TheSEED: see SP70585_1271
- PFAM: Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 76.7)Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 71.6)and 2 moreLactamase_B_3; Beta-lactamase superfamily domain (PF13483; HMM-score: 33.6)Lactamase_B_6; Metallo-beta-lactamase superfamily domain (PF16661; HMM-score: 22.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9937
- Cytoplasmic Membrane Score: 0.0004
- Cell wall & surface Score: 0
- Extracellular Score: 0.0059
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.00496
- TAT(Tat/SPI): 0.000382
- LIPO(Sec/SPII): 0.001152
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_001289493 NCBI
- UniProt: see SP70585_1271
⊟Protein sequence[edit | edit source]
- MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAGIVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SP70585_RS06330 < vicK < yycF < mutY
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1083 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]