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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 15-OCT-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae 70585
- locus tag: SP70585_RS07100 [old locus tag: SP70585_1433 ]
- pan locus tag?: PNEUPAN002720000
- symbol: SP70585_RS07100
- pan gene symbol?: glnH_3
- synonym:
- product: ABC transporter substrate-binding protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP70585_RS07100 [old locus tag: SP70585_1433 ]
- symbol: SP70585_RS07100
- product: ABC transporter substrate-binding protein
- replicon: chromosome
- strand: -
- coordinates: 1330879..1331694
- length: 816
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012468 (1330879..1331694) NCBI
- BioCyc: SP70585_RS07100 BioCyc
- MicrobesOnline: see SP70585_1433
- PneumoBrowse for strain D39V: SPV_1226 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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781ATGAAATCAAAAAAATGGATATTTGTTTTATGTAATTTTCTTGCAAGTTTCTTCTTAGTA
GCTTGCCAGTCAGGTTCTAATGGTTCTCAGTCTGCTGTGGATGCTATCAAACAAAAAGGG
AAATTAGTTGTGGCAACCAGTCCTGACTATGCACCCTTTGAATTTCAATCATTGGTTGAT
GGAAAGAACCAGGTAGTCGGTGCAGACATCGACATGGCTCAGGCTATCGCTGATGAACTT
GGGGTTAAGTTGGAAATCTTAAGCATGAGTTTTGACAATGTTTTGACCAGTCTTCAAACT
GGTAAGGCTGACCTAGCAGTTGCAGGAATTAGTGCTACTGACGAGAGAAAAGAAGTCTTT
GATTTTTCAATCCCATACTATGAAAACAAGATTAGTTTCTTGGTTCGTAAGGCTGATGTG
GAAAAATACAAGGATTTAACTAGCCTAGAAAGTGCTAATATTGCAGCCCAAAAAGGGACT
GTTCCAGAATCAATGGTCAAGGCACAATTGCCAAAAGCTCAATTAACTTCCCTAACTAAT
ATGGGTGAAGCAGTCAATGAATTGCAGGCTGGAAAAATAGATGCTGTTCATATGGATGAG
CCTGTTGCACTTAGTTATGCTGCTAAAAACGCTGGCTTAGCTGTCGCAACTGTCAGCTTG
AAGATGAAGGACGGCGACGCCAATGCCGTTGCTCTTAGAAAAAATAGTGATGATTTGAAA
GAAGTGGTAGACAAGGTCATCCAAAAACTTAAGGATGAAGGAACTTACCAAAGCTATCTT
GAAAAAGCAGCAAGTTTAACTGAAGTTGAAGAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP70585_RS07100 [old locus tag: SP70585_1433 ]
- symbol: SP70585_RS07100
- description: ABC transporter substrate-binding protein
- length: 271
- theoretical pI: 4.65337
- theoretical MW: 29233.2
- GRAVY: -0.0933579
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 160.7)and 4 moreTransport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 62.2)extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 57.2)quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein (TIGR03871; HMM-score: 31.6)aromatic cluster surface protein (TIGR04313; HMM-score: 15.1)
- TheSEED: see SP70585_1433
- PFAM: PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 190.7)and 3 moreLig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 38.6)Cystatin (CL0121) Cystatin; Cystatin domain (PF00031; HMM-score: 15.4)PBP (CL0177) NMT1_2; NMT1-like family (PF13379; HMM-score: 13.9)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helix: 1
- SignalP: Signal peptide LIPO(Sec/SPII) length 21 aa
- SP(Sec/SPI): 0.001787
- TAT(Tat/SPI): 0.000076
- LIPO(Sec/SPII): 0.997931
- Cleavage Site: CS pos: 21-22. LVA-CQ. Pr: 0.9983
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000837341 NCBI
- UniProt: see SP70585_1433
⊟Protein sequence[edit | edit source]
- MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVVATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGTVPESMVKAQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATVSLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator: AhrC*, ArgR1* see SP70585_1433
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1226 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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