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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS10920 [old locus tag: SP70585_2200 ]
  • pan locus tag?: PNEUPAN003727000
  • symbol: SP70585_RS10920
  • pan gene symbol?: gluP
  • synonym:
  • product: rhomboid family intramembrane serine protease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS10920 [old locus tag: SP70585_2200 ]
  • symbol: SP70585_RS10920
  • product: rhomboid family intramembrane serine protease
  • replicon: chromosome
  • strand: -
  • coordinates: 2007652..2008329
  • length: 678
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAAGGAAATCTTTGATAGACGTTACCCTGTGACGAGTTTCTTCCTCTTAGTGACGGCC
    TTGGTATTTTTACTAATGTTGGTCACTGCAGGCGGAAACTTTGACAGGGCAGATACATTA
    TTTCGATTTGGAGCCATGTATGGGCCAGCTATTCGCCTCTTTCCCGAGCAGGTTTGGCGT
    CTCTTGTCTGCCATTTTTGTTCATATTGGGTGGGAACATTTCATTGTTAATATGCTTTCA
    CTTTATTATCTTGGAAGGCAGGTAGAGGAGATTTTCGGTTCTAAGCAGTTTTTCTTTCTC
    TATCTTTTATCAGGAATGATGGGCAATCTCTTTGTTTTTGTATTTAGTCCTAAATCCTTA
    GCAGCAGGCGCCTCTACCTCTCTTTATGGGCTATTTGCCGCGATTATTGTTCTTCGCTAT
    GCAACTCGCAATCCTTATATTCAACAGCTAGGGCAATCCTATCTGACACTTTTTGTGGTT
    AACATTATTGGAAGTGTTCTGATTCCAGGAATCAGCCTAGCAGGCCATATCGGTGGTGCA
    GTTGGTGGCGCATTTCTAGCAGTTATCTTTCCAGTTAGAGGAGAAAAACGGATGTATAAT
    ACCAGCCAGAGATTAGGAGCGGTAGTCTTGTTCGTAGGACTCGCCATTTTGCTTTTCTAC
    AAGGGAATGGGAATGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    678

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS10920 [old locus tag: SP70585_2200 ]
  • symbol: SP70585_RS10920
  • description: rhomboid family intramembrane serine protease
  • length: 225
  • theoretical pI: 10.1796
  • theoretical MW: 25062.7
  • GRAVY: 0.793333

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.21.105?  ExPASy
    Rhomboid protease Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains
  • TIGRFAM:
    rhombosortase (TIGR03902; EC 3.4.21.-; HMM-score: 48.1)
    rhomboid family protease GlpG (TIGR04239; EC 3.4.21.105; HMM-score: 43.6)
    and 1 more
    Metabolism Transport and binding proteins Anions formate/nitrite transporter (TIGR00790; HMM-score: 8.2)
  • TheSEED: see SP70585_2200
  • PFAM:
    Rhomboid-like (CL0207) Rhomboid; Rhomboid family (PF01694; HMM-score: 122.6)
    and 2 more
    DUF1751; Eukaryotic integral membrane protein (DUF1751) (PF08551; HMM-score: 28.8)
    no clan defined DUF3043; Protein of unknown function (DUF3043) (PF11241; HMM-score: 6.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 7
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.054116
    • TAT(Tat/SPI): 0.00762
    • LIPO(Sec/SPII): 0.088171
  • predicted transmembrane helices (TMHMM): 7

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFGAMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYLLSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVVNIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILLFYKGMGM

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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